Localization of protein kinase C theta immunoreactivity to interstitial cells of Cajal in guinea-pig gastrointestinal tract

2003 ◽  
Vol 15 (2) ◽  
pp. 139-147 ◽  
Author(s):  
B. R. Southwell
Keyword(s):  
Protein Kinase C ◽  
Gastrointestinal Tract ◽  
Protein Kinase ◽  
Guinea Pig ◽  
Interstitial Cells Of Cajal ◽  
Interstitial Cells ◽  
Kinase C ◽  
Cells Of Cajal

268 Proliferation of Interstitial Cells of Cajal Occurs in Adult Mice and Is Dependent On 5HT2B Receptors and Protein Kinase C γ

2009 ◽  
Vol 136 (5) ◽  
pp. A-51 ◽  
Author(s):  
Vivek S. Tharayil ◽  
Mira M. Wouters ◽  
Jennifer E. Stanich ◽  
Michael D. Gershon ◽  
Luc Maroteaux ◽  
...  
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Interstitial Cells Of Cajal ◽  
Interstitial Cells ◽  
Adult Mice ◽  
Kinase C ◽  
Cells Of Cajal

Region-specific distribution of the P2Y4 receptor in enteric glial cells and interstitial cells of Cajal within the guinea-pig gastrointestinal tract

2006 ◽  
Vol 126-127 ◽  
pp. 299-306 ◽  
Author(s):  
Luc Van Nassauw ◽  
Anna Costagliola ◽  
Joeri Van Op den Bosch ◽  
Aldo Cecio ◽  
Jean-Marie Vanderwinden ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Guinea Pig ◽  
Glial Cells ◽  
Interstitial Cells Of Cajal ◽  
Interstitial Cells ◽  
Specific Distribution ◽  
Enteric Glial Cells ◽  
Cells Of Cajal ◽  
P2y4 Receptor

scholarly journals NMDA Induces Protein Kinase C Translocation in Guinea Pig Cerebral Synaptoneurosomes.

1991 ◽  
Vol 56 (3) ◽  
pp. 287-296 ◽  
Author(s):  
Susumu Etoh ◽  
Akemichi Baba ◽  
Heitaroh Iwata
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Guinea Pig ◽  
Kinase C

CD34 immunoreactivity and interstitial cells of Cajal in the human and mouse gastrointestinal tract

2000 ◽  
Vol 302 (2) ◽  
pp. 145-153 ◽  
Author(s):  
Jean-Marie Vanderwinden ◽  
Jüri J. Rumessen ◽  
Marc-Henri De Laet ◽  
Jean-Jacques Vanderhaeghen ◽  
Serge N. Schiffmann
Keyword(s):  
Gastrointestinal Tract ◽  
Interstitial Cells Of Cajal ◽  
Interstitial Cells ◽  
Cells Of Cajal ◽  
Human And Mouse

Muscarinic inhibition of ATP-sensitive K+ channels by protein kinase C in urinary bladder smooth muscle

1993 ◽  
Vol 265 (6) ◽  
pp. C1723-C1728 ◽  
Author(s):  
A. D. Bonev ◽  
M. T. Nelson
Keyword(s):  
Smooth Muscle ◽  
Protein Kinase C ◽  
Protein Kinase ◽  
Urinary Bladder ◽  
Guinea Pig ◽  
Smooth Muscle Cells ◽  
Katp Channels ◽  
Muscle Cells ◽  
Receptor Stimulation ◽  
Kinase C

We explored the possibility that muscarinic receptor stimulation can inhibit ATP-sensitive K+ (KATP) channels in smooth muscle cells from guinea pig urinary bladder. Whole cell K+ currents were measured in smooth muscle cells isolated from the detrusor muscle of the guinea pig bladder. Stimulation of muscarinic receptors by carbachol (CCh; 10 microM) inhibited KATP currents by 60.7%. Guanosine 5'-O-(2-thiodiphosphate) in the pipette (internal) solution prevented the CCh-induced inhibition of KATP currents. Activators of protein kinase C (PKC), a diacylglycerol analogue, and phorbol 12-myristate 13-acetate inhibited KATP currents by 63.5 and 73.9%, respectively. Blockers of PKC (bisindolylmaleimide GF-109203X and calphostin C) greatly reduced CCh inhibition of KATP currents. We propose that muscarinic receptor stimulation inhibits KATP channels in smooth muscle cells from urinary bladder through activation of PKC.

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