scholarly journals Screening for chromosomal abnormalities at 10-14 weeks: the role of ductus venosus blood flow

1998 ◽  
Vol 12 (6) ◽  
pp. 380-384 ◽  
Author(s):  
A. Matias ◽  
C. Gomes ◽  
N. Flack ◽  
N. Montenegro ◽  
K. H. Nicolaides
Keyword(s):  
Blood Flow ◽  
Chromosomal Abnormalities ◽  
Ductus Venosus

scholarly journals The role of ductus venosus blood flow assessment in screening for chromosomal abnormalities at 10-16 weeks of gestation

2001 ◽  
Vol 17 (4) ◽  
pp. 295-300 ◽  
Author(s):  
E. Antolín ◽  
C. Comas ◽  
M. Torrents ◽  
A. Muñoz ◽  
F. Figueras ◽  
...  
Keyword(s):  
Blood Flow ◽  
Chromosomal Abnormalities ◽  
Ductus Venosus

scholarly journals Improving our Knowledge in Twins: The Role of Ductus Venosus in the First Trimester

2013 ◽  
Vol 7 (4) ◽  
pp. 409-414
Author(s):  
Nuno Montenegro ◽  
Alexandra Matias
Keyword(s):  
Blood Flow ◽  
Obstet Gynecol ◽  
Chromosomal Abnormalities ◽  
First Trimester ◽  
Ductus Venosus ◽  
Abnormal Karyotype ◽  
Cardiac Defects ◽  
Twin Pregnancies ◽  
Singleton Pregnancies

ABSTRACT Ductus venosus (DV) is a tiny vessel with a central role in fetal circulation both in singletons and multiples. In the present review we detail the contribution of DV evaluation in twin pregnancies in the first trimeter of pregnancy. The higher prevalence of abnormal A-wave in fetuses with abnormal karyotype and/or cardiac defects made DV evaluation a useful marker for the screening of chromosomal abnormalities and fetal cardiac anomalies. In dichorionic (DC) pregnancies, DV blood flow assessment reproduces the role of NT in the screening for aneuploidies, just as in singleton pregnancies. In monochorionic (MC) twin pregnancies, the Doppler assessment of DV blood flow improves the detection of those at higher risk of developing twin-to-twin transfusion syndrome or growth discrepancy later in pregnancy. As for singletons, DV should be systematically evaluated in all first trimester scans for a more performant screening in multiples. How to cite this article Matias A, Montenegro N. Improving our Knowledge in Twins: The Role of Ductus Venosus in the First Trimester. Donald School J Ultrasound Obstet Gynecol 2013;7(4):409-414.

scholarly journals P01.27: The role of ductus venosus blood flow assessment in screening for chromosomal abnormalities at 10-14 weeks of gestation

2006 ◽  
Vol 28 (4) ◽  
pp. 518-518
Author(s):  
C. G. V. Murta ◽  
R. F. Bruns ◽  
L. C. S. Bussamra ◽  
E. Cordioli ◽  
P. S. Cossi ◽  
...  
Keyword(s):  
Blood Flow ◽  
Chromosomal Abnormalities ◽  
Ductus Venosus

Screening for twin-twin transfusion syndrome at 11-14 weeks of pregnancy: the key role of ductus venosus blood flow assessment

2010 ◽  
Vol 35 (2) ◽  
pp. 142-148 ◽  
Author(s):  
A. Matias ◽  
N. Montenegro ◽  
T. Loureiro ◽  
M. Cunha ◽  
S. Duarte ◽  
...  
Keyword(s):  
Blood Flow ◽  
Ductus Venosus

Reference values for Ductus Venosus pulsatility index between 11 and 13 + 6 weeks of Gestation: A Single-center Observational Study in a Tertiary Care Hospital

2021 ◽  
Author(s):  
Somayeh Haji Ahmadi ◽  
Alireza Rezaei Adariani ◽  
Ehsan Amini
Keyword(s):  
Blood Flow ◽  
Observational Study ◽  
Pulsatility Index ◽  
Chromosomal Abnormalities ◽  
Tertiary Care ◽  
First Trimester ◽  
Ductus Venosus ◽  
Care Hospital ◽  
Cross Sectional ◽  
Expert Radiologist

Abstract BackgroundThe ductus venosus pulsatility index(DVPI) has been evolved as an important marker of the first trimester screening sonography. The aim of this study is to define a reference for ductus venosus pulsatility index at 11–13 +6 weeks of gestation.MethodsIn this cross sectional observational study, 415 women with singleton pregnancies and crown lump length(CRL) between 45 and 84 mm were included. Exclusion criteria were abnormal biochemical screening results, presence of fetal structural malformation or chromosomal abnormalities such as thickened nuchal fold, abnormal perinatal outcomes, and newborns with a chromosomal abnormality. Transabdominal U/S was performed in all participants by an expert radiologist in obstetric sonography. CRL, nuchal translucency(NT), and blood flow indices of ductus venosus (DV) in each fetus were measured. The collected data were analyzed by IBM SPSS software version 20. Linear regression was performed to demonstrate the association between CRL DVPI. Further, 5th, 50th, and 95th percentiles of DV blood flow indices were calculated for each gestational age.ResultThe mean value of DVPI ranged from 1.05 at CRL 42mm to 1.3 at CRL 82mm. DVPI and CRL did not show any significant linear association (Regression coefficient B=0.001, R2=0.003, P=0.31)Conclusion: We defined means and ranges of DVPI, while determining the 5th, 50th, and 95th percentiles of DVPI for each CRL at our institution which were approximately similar to previous studies.

scholarly journals Ductus Venosus: A Love Story of 14 Years

2011 ◽  
Vol 5 (2) ◽  
pp. 141-149 ◽  
Author(s):  
Nuno Montenegro ◽  
Alexandra Matias
Keyword(s):  
Blood Flow ◽  
Chromosomal Abnormalities ◽  
False Positive Rate ◽  
First Trimester ◽  
Nuchal Translucency ◽  
Ductus Venosus ◽  
Love Story ◽  
Positive Rate ◽  
Trimester Screening ◽  
Twin Pregnancies

ABSTRACT Ductus venosus is a tiny vessel with a central role in fetal circulation. Combining B-mode with color and pulsed Doppler is feasible to identify this vessel and evaluate the blood flow waveform at 11 to 13 weeks. The higher prevalence of abnormal A-wave in fetuses with abnormal karyotype and/or cardiac defects turned DV evaluation into a useful marker for chromosomal abnormalities and cardiopathies. Even when combined with nuchal translucency (NT) or biochemical markers, DV blood flow evaluation contributes to an increase in sensitivity and reduces false-positive rate. Abnormal ductal flow is also related to a worse fetal and perinatal outcome. In monochorionic twin pregnancies, in addition to NT measurement at 11 to 14 weeks, the Doppler assessment of DV blood flow increases relevantly the performance of screening for those at higher risk of developing twin-to-twin transfusion syndrome. This story of 14 years surely contributed to change the way first trimester screening is being implemented.

scholarly journals Ductus venosus blood flow assessment at 10-16 weeks' gestation and chromosomal abnormalities

2001 ◽  
Vol 18 ◽  
pp. P12-P12
Author(s):  
E. Antolín ◽  
C. Comas ◽  
M. Echevarría ◽  
M. Torrents ◽  
A. Muñoz ◽  
...  
Keyword(s):  
Blood Flow ◽  
Chromosomal Abnormalities ◽  
Ductus Venosus

scholarly journals Numerical investigation of the haemodynamics in the human fetal umbilical vein/ductus venosus based on the experimental data

2016 ◽  
Vol 36 (5) ◽  
Author(s):  
Taraneh Rezaee ◽  
Kamran Hassani
Keyword(s):  
Blood Flow ◽  
Chromosomal Abnormalities ◽  
Early Stage ◽  
Umbilical Vein ◽  
Computational Simulation ◽  
Vena Cava ◽  
Ductus Venosus ◽  
Clinical Feature ◽  
Doppler Measurement ◽  
Fetal Circulation

Abortion of the fetus due to a disease, in an early stage of pregnancy, has been dramatically increased in the last decades. There is a still lack of knowledge on the various types of diseases which lead fetus to a vulnerable circumstance. The transport of oxygenated blood from the placenta to the human fetus has been an important clinical feature in Doppler velocimetry studies, especially the ductus venosus (DV). The DV connects intra-abdominal portion of the umbilical vein and the inferior vena cava (IVC) at the inlet of the right atrium and is, therefore, important when examining the fetus state of health. An abnormal flow in the DV can indicate a fetal disease such as, chromosomal abnormalities, cardiac defect, hypoxaemia and intrauterine growth restriction (IUGR). The blood flow in the fetal circulation has not been investigated much in detail. The blood flow in the fetal circulation provides necessary information for physician to make a suitable decision on abortion or alternative medical practice before or even after birth. The present study performed a comparative study to quantify the blood velocity in DV by a combination approach based on 3D computational simulation and Doppler measurement. The results showed that the velocity value in DV is significant and can be considered as an indicator of any kind of disease in fetal. The nodal displacement of the model was also analysed. It shows that DV tolerates a higher level of displacement compared with the other regions of the model, whereas the nodal pressure shows different results as the lowest values are located in DV.

Sign in / Sign up

Export Citation Format

Share Document