scholarly journals Role of the Outward Delayed Rectifier K+ Current in Ceramide-Induced Caspase Activation and Apoptosis in Cultured Cortical Neurons

2001 ◽  
Vol 73 (3) ◽  
pp. 933-941 ◽  
Author(s):  
Shan Ping Yu ◽  
Chen-Hsiung Yeh ◽  
Frank Gottron ◽  
Xin Wang ◽  
Margaret C. Grabb ◽  
...  
Keyword(s):  
Cortical Neurons ◽  
Delayed Rectifier ◽  
Caspase Activation ◽  
Cultured Cortical Neurons ◽  
K Current

The antidepressant citalopram inhibits delayed rectifier outward K+ current in mouse cortical neurons

2011 ◽  
Vol 90 (1) ◽  
pp. 324-336 ◽  
Author(s):  
Xiao-Qin Zhan ◽  
Yan-Lin He ◽  
Jin-Jing Yao ◽  
Jia-Li Zhuang ◽  
Yan-Ai Mei
Keyword(s):  
Cortical Neurons ◽  
Delayed Rectifier ◽  
K Current

Role of slow delayed rectifier K+-current in QT prolongation in the alloxan-induced diabetic rabbit heart

2008 ◽  
Vol 192 (3) ◽  
pp. 359-368 ◽  
Author(s):  
Cs. Lengyel ◽  
L. Virág ◽  
P. P. Kovács ◽  
A. Kristóf ◽  
P. Pacher ◽  
...  
Keyword(s):  
Rabbit Heart ◽  
Qt Prolongation ◽  
Delayed Rectifier ◽  
Diabetic Rabbit ◽  
K Current

Autonomic regulation of delayed rectifier K+ current in mammalian heart involves G proteins

1989 ◽  
Vol 257 (3) ◽  
pp. H818-H823 ◽  
Author(s):  
R. D. Harvey ◽  
J. R. Hume
Keyword(s):  
Ventricular Myocytes ◽  
Autonomic Regulation ◽  
Delayed Rectifier ◽  
Pacemaker Activity ◽  
Cholinergic Stimulation ◽  
K Current ◽  
Guanine Nucleotide Binding ◽  
Nucleotide Binding Proteins ◽  
Guanine Nucleotide Binding Proteins

The role of adrenergic and cholinergic stimulation in regulating the delayed outward K+ current (IK) was examined by using isolated guinea pig ventricular myocytes. Isoproterenol (ISO) stimulated IK in a reversible manner. Similar effects were seen by directly stimulating adenylate cyclase with forskolin (FSK). The responses to ISO and FSK were reversed by concurrent application of acetylcholine (ACh), but ACh alone did not affect IK. When a nonhydrolyzable analogue of guanosine 5'-triphosphate was introduced intracellularly, in the presence of extracellular ISO, IK was irreversibly stimulated. In cells pretreated with pertussis toxin the ACh response was blocked. These results suggest that autonomic regulation of IK is similar to that of the Ca2+ current and involves guanine nucleotide-binding proteins. This has important implications with respect to autonomic control of action potential duration and pacemaker activity in the heart.

Presence and functional role of the rapidly activating delayed rectifier K+ current in left and right atria of adult mice

2010 ◽  
Vol 649 (1-3) ◽  
pp. 14-22 ◽  
Author(s):  
Hiroko Nakamura ◽  
Wei-Guang Ding ◽  
Mitsuru Sanada ◽  
Kengo Maeda ◽  
Hiromichi Kawai ◽  
...  
Keyword(s):  
Functional Role ◽  
Delayed Rectifier ◽  
Adult Mice ◽  
K Current ◽  
Left And Right ◽  
Right Atria

scholarly journals Role of KCNQ1 in the Cell Swelling-Induced Enhancement of the Slowly Activating Delayed Rectifier K+ Current.

2002 ◽  
Vol 52 (1) ◽  
pp. 31-39 ◽  
Author(s):  
Tomoyuki Kubota ◽  
Minoru Horie ◽  
Makoto Takano ◽  
Hidetada Yoshida ◽  
Hideo Otani ◽  
...  
Keyword(s):  
Cell Swelling ◽  
Delayed Rectifier ◽  
K Current

P3-077: Protective role of n-trans-feruloyltyramine against beta-amyloid-peptide-induced neurotoxicity, bax, caspase and ROS in rat-cultured cortical neurons

2012 ◽  
Vol 8 (4S_Part_13) ◽  
pp. P479-P480
Author(s):  
Wipawan Thangnipon ◽  
Nirut Suwanna ◽  
Narisorn Kitiyanant ◽  
Rungtip Soi-ampornkul ◽  
Bamroong Munyoo ◽  
...  
Keyword(s):  
Cortical Neurons ◽  
Beta Amyloid ◽  
Protective Role ◽  
Amyloid Peptide ◽  
Beta Amyloid Peptide ◽  
Cultured Cortical Neurons
Sign in / Sign up

Export Citation Format

Share Document