Heart Transplantation for Complex Congenital Heart Disease: Will It Become an Arcane Activity?

2016 ◽  
Vol 28 (2) ◽  
pp. 498-499 ◽  
Author(s):  
James K. Kirklin
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Heart Transplantation ◽  
Congenital Heart ◽  
Complex Congenital Heart Disease

Systemic Venous Reconstructions During Pediatric Heart Transplantation

2021 ◽  
Vol 12 (5) ◽  
pp. 583-588
Author(s):  
Firat Altin ◽  
Bahaaldin Alsoufi ◽  
Kirk Kanter ◽  
Shriprasad R. Deshpande
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Heart Transplantation ◽  
Congenital Heart ◽  
Superior Vena ◽  
Complex Congenital Heart Disease ◽  
Venous Reconstruction ◽  
Venous Anomalies ◽  
Surgical Data ◽  
Pediatric Heart Transplantation

Background: Congenital heart disease continues to be an important indication for pediatric heart transplantation (HT) and is often complicated by systemic venous anomalies. The need for reconstruction, surgical technique used, as well as the outcomes of these have limited documentation. Methods: Descriptive, retrospective study of patients transplanted at Emory University between 2006 and 2017. We reviewed surgical data, follow-up, and interventions for patients necessitating venous reconstruction during transplantation. Results: A total of 179 transplants were performed during the time period of which 74 (41%) required systemic venous reconstruction. Mean age at transplant was 6.3 (±6.16) years, and 74.3% of these patients carried a diagnosis of single ventricle; 51 (68.9%) of 74 patients required pulmonary artery reconstruction at the time of HT. Forty patients required superior vena caval reconstruction, while 22 patients required inferior vena caval reconstruction due to prior palliation or anomaly. Venous anomalies along with other anatomic features necessitated biatrial transplantation in four patients. Posttransplant evaluation revealed systemic venous stenosis in 14 (18.9%) of 74 patients. Eight (10.8%) patients required 12 interventions for the systemic veins. Patients with bilateral Glenn anastomosis prior to transplant were at high risk for the development of stenosis and needing interventions. Systemic venous complications were uncommon in those with native systemic veins without Glenn or Fontan procedure. Conclusion: Systemic venous reconstruction needs are high in pediatric HT. Posttransplant stenosis and the need for interventions are relatively common. Current techniques for systemic venous reconstruction for complex congenital heart disease patients may deserve further review to optimize these outcomes.

scholarly journals Is heart transplantation for complex congenital heart disease a good option? A 25-year single centre experience†

2012 ◽  
Vol 43 (3) ◽  
pp. 605-611 ◽  
Author(s):  
Francesco Seddio ◽  
Natalyia Gorislavets ◽  
Attilio Iacovoni ◽  
Diego Cugola ◽  
Alessandra Fontana ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Heart Transplantation ◽  
Congenital Heart ◽  
Good Option ◽  
Complex Congenital Heart Disease ◽  
Single Centre ◽  
Single Centre Experience

scholarly journals Heart Transplantation in Congenital Heart Disease: In Whom to Consider and When?

2013 ◽  
Vol 2013 ◽  
pp. 1-12 ◽  
Author(s):  
Christine H. Attenhofer Jost ◽  
Dörthe Schmidt ◽  
Michael Huebler ◽  
Christian Balmer ◽  
Georg Noll ◽  
...  
Keyword(s):  
Heart Failure ◽  
Congenital Heart Disease ◽  
Heart Disease ◽  
Heart Transplantation ◽  
Lung Transplantation ◽  
Congenital Heart ◽  
Complex Congenital Heart Disease ◽  
Eisenmenger’S Syndrome ◽  
Number Of Patients ◽  
Increased Risk

Due to impressive improvements in surgical repair options, even patients with complex congenital heart disease (CHD) may survive into adulthood and have a high risk of end-stage heart failure. Thus, the number of patients with CHD needing heart transplantation (HTx) has been increasing in the last decades. This paper summarizes the changing etiology of causes of death in heart failure in CHD. The main reasons, contraindications, and risks of heart transplantation in CHD are discussed and underlined with three case vignettes. Compared to HTx in acquired heart disease, HTx in CHD has an increased risk of perioperative death and rejection. However, outcome of HTx for complex CHD has improved over the past 20 years. Additionally, mechanical support options might decrease the waiting list mortality in the future. The number of patients needing heart-lung transplantation (especially for Eisenmenger’s syndrome) has decreased in the last years. Lung transplantation with intracardiac repair of a cardiac defect is another possibility especially for patients with interatrial shunts. Overall, HTx will remain an important treatment option for CHD in the near future.

scholarly journals Heart transplantation in the setting of complex congenital heart disease and physiologic single lung

2015 ◽  
Vol 150 (6) ◽  
pp. 1465-1472 ◽  
Author(s):  
Warren A. Zuckerman ◽  
Marc E. Richmond ◽  
Teresa M. Lee ◽  
Emile A. Bacha ◽  
Paul J. Chai ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Heart Transplantation ◽  
Congenital Heart ◽  
Complex Congenital Heart Disease

scholarly journals Orthotopic heart transplantation for complex congenital heart disease

1990 ◽  
Vol 99 (3) ◽  
pp. 484-492 ◽  
Author(s):  
John E. Mayer ◽  
Stanton Perry ◽  
Patricia O'Brien ◽  
Antonio Perez-Atayde ◽  
Richard A. Jonas ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Heart Transplantation ◽  
Congenital Heart ◽  
Orthotopic Heart Transplantation ◽  
Complex Congenital Heart Disease
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