Short-term hemodynamic support with bearingless, magnetically levitated paracorporal centrifugal pumps

2009 ◽  
Vol 56 (S 01) ◽  
Author(s):  
JFM Bechtel ◽  
EI Charitos ◽  
T Hanke ◽  
M Misfeld ◽  
C Schmidtke ◽  
...  
Keyword(s):  
Centrifugal Pumps ◽  
Short Term ◽  
Hemodynamic Support ◽  
Magnetically Levitated

Outcomes of patients with right ventricular failure requiring short-term hemodynamic support with the Impella RP device

2018 ◽  
Vol 37 (12) ◽  
pp. 1448-1458 ◽  
Author(s):  
Mark Anderson ◽  
D. Lynn Morris ◽  
Daniel Tang ◽  
George Batsides ◽  
Ajay Kirtane ◽  
...  
Keyword(s):  
Right Ventricular ◽  
Right Ventricular Failure ◽  
Ventricular Failure ◽  
Short Term ◽  
Hemodynamic Support

scholarly journals The Role of Hemodynamic Support in High-risk Percutaneous Coronary Intervention

2020 ◽  
Vol 14 ◽  
Author(s):  
Charles Simonton ◽  
Craig Thompson ◽  
Jason R Wollmuth ◽  
D Lynn Morris ◽  
Thom G Dahle
Keyword(s):  
Percutaneous Coronary Intervention ◽  
High Risk ◽  
Heart Function ◽  
Coronary Intervention ◽  
Special Focus ◽  
Centrifugal Pumps ◽  
Hemodynamic Support ◽  
Improved Outcomes ◽  
Percutaneous Coronary ◽  
Support Devices

Patients with advanced age, complex coronary anatomy, and multiple comorbidities are often unsuitable for surgical revascularization. In this setting, hemodynamic support devices are used as an adjunct to percutaneous coronary intervention to maintain hemodynamic stability and enable optimal revascularization. This article provides an overview of percutaneous hemodynamic support devices currently used in clinical practice for high-risk percutaneous coronary intervention. These include the intra-aortic balloon pump, centrifugal pumps (TandemHeart, venous arterial extracorporeal membrane oxygenation), and micro-axial Impella pump. The hemodynamic effects, clinical evidence supporting improved outcomes and recovery of heart function, and associated complications with these devices are highlighted, with a special focus on Impella pumps.

Aortix: a novel intra-aortic entrainment pump

2020 ◽  
Author(s):  
Navin K Kapur ◽  
Michele L Esposito ◽  
Evan Whitehead
Keyword(s):  
Continuous Flow ◽  
Mechanical Circulatory Support ◽  
Axial Flow ◽  
Decompensated Heart Failure ◽  
Coronary Intervention ◽  
Circulatory Support ◽  
Short Term ◽  
Hemodynamic Support ◽  
Axial Flow Pump ◽  
Flow Pump

Use of short-term mechanical circulatory support pumps for cardiogenic shock, decompensated heart failure and high-risk coronary intervention is growing. The Aortix™ device (Procyrion, TX, USA) is the first axial-flow pump positioned in the aorta and is designed to provide short-term hemodynamic support. This review discusses the field of continuous flow aortic pumps and focuses specifically on emerging preclinical and clinical data supporting the development of these technologies.

scholarly journals Postcardiotomy Mechanical Circulatory Support in Two Infants with Williams’ Syndrome

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Constantinos A. Contrafouris ◽  
Andrew C. Chatzis ◽  
Meletios A. Kanakis ◽  
Prodromos A. Azariadis ◽  
Fotios A. Mitropoulos
Keyword(s):  
Aortic Stenosis ◽  
Extracorporeal Membrane Oxygenation ◽  
Williams Syndrome ◽  
Mechanical Circulatory Support ◽  
Circulatory Support ◽  
Centrifugal Pumps ◽  
Short Term ◽  
Perioperative Morbidity ◽  
Supravalvar Aortic Stenosis ◽  
Myocardial Lesions

Supravalvar aortic stenosis (SVAS) in patients with Williams’ syndrome is often accompanied by coronary, pulmonary, and even myocardial lesions and therefore associated with increased perioperative morbidity and mortality. Extracorporeal membrane oxygenation (ECMO) provides reliable short-term mechanical circulatory support to patients, especially young, in acute postoperative cardiac failure when conventional means are ineffective. The incorporation of centrifugal pumps in these systems has made their use more efficient and less traumatic. We describe our experience of using the Levitronix CentriMag pump in two patients with Williams' syndrome who underwent surgical correction of supravalvular aortic stenosis.

scholarly journals A Case of Simultaneous Liver Transplantation and Mitral Valve Replacement in a HCV Cirrhotic Patient with Severe Mitral Valve Stenosis

2020 ◽  
pp. 1-3
Author(s):  
Andrea De Gasperi ◽  
Andrea De Gasperi ◽  
Elena Roselli ◽  
Marcello Guarnieri
Keyword(s):  
Liver Transplantation ◽  
Mitral Valve ◽  
Valve Replacement ◽  
Mitral Valve Replacement ◽  
Graft Function ◽  
Chronic Atrial Fibrillation ◽  
Mitral Valve Stenosis ◽  
Combined Surgery ◽  
Short Term ◽  
Hemodynamic Support

We report a case ofsimultaneous liver transplantation and mitral valve replacement in a 53 years old woman suffering for a severe HCV - related liver cirrhosis (CHILD C12, MELD 26), severe mitral stenosis and chronic atrial fibrillation. Cardiac surgery was performed on cardiopulmonary bypass with full heparinization and cardiac arrest and preceded liver transplantation. The patient was weaned on postoperative day 2 from mechanical ventilation and on postoperative day 5 from hemodynamic support and renal replacement therapy. She was transferred to the ward on POD 12. On POD 20 she was readmitted to ICU for acute kidney failure, worsening graft function, sepsis and the suspicion of acute rejection. On POD 56 after a long intensive treatment, the patient eventually died from an intracranial hemorrhage. This complex combined surgery carries a high burden of morbidity and mortality but showed a good result in the short term.

Conceptual short-term memory (CSTM) supports core claims of Christiansen and Chater

2016 ◽  
Vol 39 ◽  
Author(s):  
Mary C. Potter
Keyword(s):  
Working Memory ◽  
Rapid Serial Visual Presentation ◽  
Language Comprehension ◽  
Short Term Memory ◽  
Visual Presentation ◽  
Long Term Memory ◽  
Short Term ◽  
Term Memory ◽  
Use Of Knowledge

AbstractRapid serial visual presentation (RSVP) of words or pictured scenes provides evidence for a large-capacity conceptual short-term memory (CSTM) that momentarily provides rich associated material from long-term memory, permitting rapid chunking (Potter 1993; 2009; 2012). In perception of scenes as well as language comprehension, we make use of knowledge that briefly exceeds the supposed limits of working memory.

Ultrastructural Changes of Canine Kidneys During 24-Hour Perfusion on a LI-400 Preservation System

1971 ◽  
Vol 29 ◽  
pp. 316-317
Author(s):  
M. O. Magnusson ◽  
D. G. Osborne ◽  
T. Shimoji ◽  
W. S. Kiser ◽  
W. A. Hawk
Keyword(s):  
Electron Microscopy ◽  
Electrolyte Solution ◽  
Ultrastructural Changes ◽  
Midline Incision ◽  
Short Term ◽  
Pentobarbital Anesthesia ◽  
Pulsatile Perfusion

Short term experimental and clinical preservation of kidneys is presently best accomplished by hypothermic continuous pulsatile perfusion with cryoprecipitated and millipore filtered plasma. This study was undertaken to observe ultrastructural changes occurring during 24-hour preservation using the above mentioned method.A kidney was removed through a midline incision from healthy mongrel dogs under pentobarbital anesthesia. The kidneys were flushed immediately after removal with chilled electrolyte solution and placed on a LI-400 preservation system and perfused at 8-10°C. Serial kidney biopsies were obtained at 0-½-1-2-4-8-16 and 24 hours of preservation. All biopsies were prepared for electron microscopy. At the end of the preservation period the kidneys were autografted.

Polychlorinated biphenyl induced hepatocyte alterations

1987 ◽  
Vol 45 ◽  
pp. 716-717
Author(s):  
D.N. Collins ◽  
J.N. Turner ◽  
K.O. Brosch ◽  
R.F. Seegal
Keyword(s):  
Lipid Droplets ◽  
Wistar Rats ◽  
Homovanillic Acid ◽  
Polychlorinated Biphenyl ◽  
Corn Oil ◽  
Environmental Pollutants ◽  
Short Term ◽  
Pcb Congeners ◽  
Urinary Levels ◽  
The Brain

Polychlorinated biphenyls (PCBs) are a ubiquitous class of environmental pollutants with toxic and hepatocellular effects, including accumulation of fat, proliferated smooth endoplasmic recticulum (SER), and concentric membrane arrays (CMAs) (1-3). The CMAs appear to be a membrane storage and degeneration organelle composed of a large number of concentric membrane layers usually surrounding one or more lipid droplets often with internalized membrane fragments (3). The present study documents liver alteration after a short term single dose exposure to PCBs with high chlorine content, and correlates them with reported animal weights and central nervous system (CNS) measures. In the brain PCB congeners were concentrated in particular regions (4) while catecholamine concentrations were decreased (4-6). Urinary levels of homovanillic acid a dopamine metabolite were evaluated (7).Wistar rats were gavaged with corn oil (6 controls), or with a 1:1 mixture of Aroclor 1254 and 1260 in corn oil at 500 or 1000 mg total PCB/kg (6 at each level).

Acetaminophen: Macula densa hypersecretory activity by induced hepatotoxicity

1987 ◽  
Vol 45 ◽  
pp. 934-935
Author(s):  
S.S. Poolsawat ◽  
C.A. Huerta ◽  
S.TY. Lae ◽  
G.A. Miranda
Keyword(s):  
Cell Proliferation ◽  
Liver Function ◽  
Chronic Inflammation ◽  
Foam Cell ◽  
Term Effect ◽  
Short Term ◽  
Drug Induced ◽  
Experimental Induction ◽  
Tissue Alterations ◽  
Toxic Responses

Introduction. Experimental induction of altered histology by chemical toxins is of particular importance if its outcome resembles histopathological phenomena. Hepatotoxic drugs and chemicals are agents that can be converted by the liver into various metabolites which consequently evoke toxic responses. Very often, these drugs are intentionally administered to resolve an illness unrelated to liver function. Because of hepatic detoxification, the resulting metabolites are suggested to be integrated into the macromolecular processes of liver function and cause an array of cellular and tissue alterations, such as increased cytoplasmic lysis, centrilobular and localized necroses, chronic inflammation and “foam cell” proliferation of the hepatic sinusoids (1-4).Most experimentally drug-induced toxicity studies have concentrated primarily on the hepatic response, frequently overlooking other physiological phenomena which are directly related to liver function. Categorically, many studies have been short-term effect investigations which seldom have followed up the complications to other tissues and organs when the liver has failed to function normally.

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