Chemical investigation and evaluation of analgesic and anti-inflammatory activies of Copaifera langsdorffii leaf extract

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
RA Furtado ◽  
MN da Silva ◽  
CTV Bernardes ◽  
JK Bastos
Keyword(s):  
Leaf Extract ◽  
Chemical Investigation ◽  
Copaifera Langsdorffii ◽  
Anti Inflammatory

Anti-inflammatory activity of leaf extract and fractions of Bursera simaruba (L.) Sarg (Burseraceae)

2004 ◽  
Vol 92 (1) ◽  
pp. 129-133 ◽  
Author(s):  
B. Noguera ◽  
E. Dı́az ◽  
M.V. Garcı́a ◽  
A.San Feliciano ◽  
J.L. López-Perez ◽  
...  
Keyword(s):  
Leaf Extract ◽  
Inflammatory Activity ◽  
Bursera Simaruba ◽  
Anti Inflammatory

scholarly journals Syzygium aqueum: A Polyphenol- Rich Leaf Extract Exhibits Antioxidant, Hepatoprotective, Pain-Killing and Anti-inflammatory Activities in Animal Models

2018 ◽  
Vol 9 ◽  
Author(s):  
Mansour Sobeh ◽  
Mona F. Mahmoud ◽  
Ganna Petruk ◽  
Samar Rezq ◽  
Mohamed L. Ashour ◽  
...  
Keyword(s):  
Animal Models ◽  
Leaf Extract ◽  
Anti Inflammatory

scholarly journals Anti-Inflammatory Activity of Populus deltoides Leaf Extract via Modulating NF-κB and p38/JNK Pathways

2018 ◽  
Vol 19 (12) ◽  
pp. 3746 ◽  
Author(s):  
Ye Jeong ◽  
Mi-Young Lee
Keyword(s):  
Nitric Oxide ◽  
Protein Kinase ◽  
Leaf Extract ◽  
Populus Deltoides ◽  
Nuclear Translocation ◽  
Mapk Signaling ◽  
Mitogen Activated Protein Kinase ◽  
Inflammatory Activity ◽  
No Production ◽  
Anti Inflammatory

Populus deltoides, known as eastern cottonwood, has been commonly used as a medicinal plant. The aim of the present study was to investigate the mechanism underlying the anti-inflammatory activity of P. deltoides leaf extract (PLE). PLE effectively inhibited the expression of inducible nitric oxide synthase (iNOS) and nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells, but not that of cyclooxygenase-2 (COX-2) and prostaglandin E2. Proinflammatory tumor necrosis factor alpha (TNF-α) levels were also reduced by the extract. PLE inhibited the phosphorylation of nuclear factor-kappa B (NF-κB) and inhibitor of Kappa Bα (IκBα), and blunted LPS-triggered enhanced nuclear translocation of NF-κB p65. In mitogen-activated protein kinase (MAPK) signaling, PLE effectively decreased the phosphorylation of p38 and c-Jun N-terminal protein kinase (JNK), but not of extracellular signal-regulated kinase 1/2 (ERK1/2). Taken together, these results suggest that anti-inflammatory activity of P. deltoides leaf extract might be driven by iNOS and NO inhibition mediated by modulation of the NF-κB and p38/JNK signaling pathways.

scholarly journals Analgesic and Anti-Inflammatory Activity of Total Crude Leaf Extract of <i>Phytolacca dodecandra</i> in Wistar Albino Rats

2019 ◽  
Vol 10 (03) ◽  
pp. 259-271
Author(s):  
Loyce Nakalembe ◽  
Josephine N. Kasolo ◽  
Edward Nyatia ◽  
Aloysius Lubega ◽  
Godfrey S. Bbosa
Keyword(s):  
Leaf Extract ◽  
Inflammatory Activity ◽  
Albino Rats ◽  
Phytolacca Dodecandra ◽  
Crude Leaf Extract ◽  
Anti Inflammatory ◽  
Wistar Albino Rats

scholarly journals Green synthesis of silver nanoparticles from Lonicera japonica leaf extract and their anti‐inflammatory and antibacterial effects

2020 ◽  
Vol 15 (2) ◽  
pp. 90-95
Author(s):  
Luyun Yan ◽  
Beibei Qiu ◽  
Tongtong Li ◽  
Dandan Wu ◽  
Jinhua Zhu ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Green Synthesis ◽  
Leaf Extract ◽  
Lonicera Japonica ◽  
Antibacterial Effects ◽  
Anti Inflammatory

scholarly journals Preliminary assessment of the anti-inflammatory and analgesic effects of methanol leaf extract of Cussonia barteri (Araliaceae) in rodents

2019 ◽  
Vol 65 (3) ◽  
pp. 22-31
Author(s):  
Ighodaro Igbe ◽  
Osaze Edosuyi ◽  
Agbonlahor Okhuarobo ◽  
Adarki Pongri ◽  
Nkechi Maduako ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Analgesic Effect ◽  
Leaf Extract ◽  
Methanol Extract ◽  
Tail Flick ◽  
Hot Plate ◽  
Analgesic Effects ◽  
Paw Oedema ◽  
Anti Inflammatory ◽  
Ear Oedema

Summary Introduction: Potato (Solanum tuberosum L.) is an important vegetable crop in Syria. Potato tuber moth Cussonia barteri is a small tree that grows in the sub-Saharan part of Africa. Various parts of the plant are used for the treatment of a variety of ailments in ethno-medicine. Objective: To evaluate the anti-inflammatory and analgesic effect of the methanol leaf extract of Cussonia barteri. Material and methods: The leaves were air-dried, powdered and repeatedly extracted with methanol using a Soxhlet apparatus. The resulting methanol extract (100, 200 and 400 mg/kg) was evaluated for anti-inflammatory activity using carrageenan-induced paw oedema, xylene-induced ear oedema and formalin-induced arthritis tests. Analgesic effect was evaluated using acetic acid-induced mouse writhing, hot plate and tail flick tests. Results: All doses of the extract significantly (p<0.05) reduced carrageenan-induced paw oedema, however the 400 mg/kg dose gave a sustained effect. The extract significantly inhibited xylene induced ear oedema at all doses. There were no significant (p>0.05) reductions in paw swellings due to formalin. In the acetic acid induced writhing test, the extract significantly (p<0.05) decreased writhing at 400 mg/kg only. Reaction times were not significantly different from the control in the hot plate and tail flick tests. Conclusion: This study has shown that the methanol extract possesses acute anti-inflammatory and peripherally mediated analgesic effects.

scholarly journals Analgesic, anti-inflammatory and antipyretic activities of ethanol extract of Annona senegalensis leaves in experimental animal models

2020 ◽  
Vol 9 (10) ◽  
pp. 1477
Author(s):  
Anthony U. Megwas ◽  
Godwin C. Akuodor ◽  
Leo C. Chukwu ◽  
Daniel O. Aja ◽  
Edmund M. Okorie ◽  
...  
Keyword(s):  
Animal Models ◽  
Leaf Extract ◽  
Therapeutic Potential ◽  
Ethanol Extract ◽  
Tail Flick ◽  
Experimental Animal Models ◽  
Antipyretic Activity ◽  
Egg Albumen ◽  
Anti Inflammatory ◽  
Abdominal Constriction

Background: This study was carried out to establish the analgesic, anti-inflammatory and antipyretic effects of the ethanol extract of Anonna senegalensis leaves in experimental animals.Methods: The analgesic activity was measured using the abdominal constriction and tail flick tests. The anti-inflammatory activity was performed using xylene and egg-albumen paw induced tests, while the antipyretic activity was measured using brewer’s yeast and 2, 4 dinitrophenol induced pyrexia tests, respectively.Results: The leaf extract at all doses used exhibited significant (p<0.05) analgesic, anti-inflammatory and antipyretic activities.Conclusions: Results show that ethanol leaf extract of Anonna senegalensis possess therapeutic potential against pains and feverish conditions, supporting the claims of its this plant as remedy for similar ailments.

scholarly journals Antinociceptive and Anti-Inflammatory Activities ofTelfairia occidentalisHydroethanolic Leaf Extract (Cucurbitaceae)

2015 ◽  
Vol 18 (10) ◽  
pp. 1157-1163 ◽  
Author(s):  
Abidemi James Akindele ◽  
Joy Awulika Oladimeji-Salami ◽  
Blessing Amarachi Usuwah
Keyword(s):  
Leaf Extract ◽  
Anti Inflammatory

scholarly journals An in vivo immunomodulatory and anti-inflammatory study of fermented Dendropanax morbifera Léveille leaf extract

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Biruk Tesfaye Birhanu ◽  
Jin-Yoon Kim ◽  
Md. Akil Hossain ◽  
Jae-Won Choi ◽  
Sam-Pin Lee ◽  
...  
Keyword(s):  
Leaf Extract ◽  
Dendropanax Morbifera ◽  
Anti Inflammatory

Green synthesis of a MnO-GO-Ag nanocomposite using leaf extract of Fagonia arabica and its antioxidant and anti-inflammatory performance

2022 ◽  
Vol 29 ◽  
pp. 100835
Author(s):  
Sana Mansoor ◽  
Sammia Shahid ◽  
Mohsin Javed ◽  
Muhammad Saad ◽  
Shahid Iqbal ◽  
...  
Keyword(s):  
Green Synthesis ◽  
Leaf Extract ◽  
Anti Inflammatory
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