Long-term results of electrical stimulation of the lower esophageal sphincter for the treatment of gastroesophageal reflux disease

Endoscopy ◽  
2013 ◽  
Vol 45 (08) ◽  
pp. 595-604 ◽  
Author(s):  
L. Rodríguez ◽  
P. Rodriguez ◽  
B. Gómez ◽  
J. Ayala ◽  
D. Oksenberg ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Lower Esophageal Sphincter ◽  
Reflux Disease ◽  
Long Term Results ◽  
Esophageal Sphincter ◽  
Stimulation Of

scholarly journals Two-year results of intermittent electrical stimulation of the lower esophageal sphincter treatment of gastroesophageal reflux disease

Surgery ◽  
2015 ◽  
Vol 157 (3) ◽  
pp. 556-567 ◽  
Author(s):  
Leonardo Rodríguez ◽  
Patricia Rodriguez ◽  
Beatriz Gómez ◽  
Juan C. Ayala ◽  
Danny Oxenberg ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Lower Esophageal Sphincter ◽  
Reflux Disease ◽  
Esophageal Sphincter ◽  
Stimulation Of

Long-term results of electrical stimulation of the lower esophageal sphincter for treatment of proximal GERD

2014 ◽  
Vol 28 (12) ◽  
pp. 3293-3301 ◽  
Author(s):  
Toshitaka Hoppo ◽  
Leonardo Rodríguez ◽  
Edy Soffer ◽  
Michael D. Crowell ◽  
Blair A. Jobe
Keyword(s):  
Electrical Stimulation ◽  
Lower Esophageal Sphincter ◽  
Long Term Results ◽  
Esophageal Sphincter ◽  
Stimulation Of

scholarly journals Wirelessly Powered Endoscopically Implantable Devices into the Submucosa as the Possible Treatment of Gastroesophageal Reflux Disease

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
J. Hajer ◽  
M. Novák ◽  
J. Rosina
Keyword(s):  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Lower Esophageal Sphincter ◽  
Reflux Disease ◽  
Muscularis Propria ◽  
Western World ◽  
Common Disease ◽  
Number Of Patients ◽  
Esophageal Sphincter ◽  
Stimulation Of

Gastroesophageal reflux disease (GERD) is a rather common disease with a prevalence reaching up to 10 or 20% in the western world. The most specific symptoms which point to the diagnosis of GERD are feelings of heartburn and the regurgitation of acidic stomach contents into the esophagus. However, a certain number of patients do not respond to standard therapy, and in these cases, it is necessary to resort to other treatment methods, such as laparoscopic fundoplication or electrostimulation of the lower esophageal sphincter. The aim of our work was to design and manufacture a miniature, battery-less stimulator to provide electric stimulation of the lower esophageal sphincter, which could be implanted deep into the submucosa of the distal esophagus. The main goal was to provide a battery-less system as opposed to traditional battery neurostimulators to reduce the size and weight of the device. An electronic prototype of a wirelessly powered implantable device was developed. We used animal models for the experiments. The device is designed to treat GERD via electrical stimulation of the muscularis propria. It is implanted into the submucosal pocket by the lower esophageal sphincter with an endoscope. This method of implantation is superior to esophageal stimulators used today because of very low invasiveness of the surgery. Bipolar neurostimulation via two gold-plated leads is provided. The device does not have any source of energy; it is powered wirelessly which reduces the risk of potential battery leakage and reduces the overall dimensions.

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