Retargeting of oncolytic adenoviruses by bispecific adapter molecules reduces viral liver load and improves therapy by triggering antigen-specific CD8 T-cell responses

A Kloos; E Gürlevik; N Woller; CI Ureche; MP Manns; R Gerardy-Schahn; S Kubicka; F Kühnel

doi:10.1055/s-0033-1360992

Retargeting of oncolytic adenoviruses by bispecific adapter molecules reduces viral liver load and improves therapy by triggering antigen-specific CD8 T-cell responses

Zeitschrift für Gastroenterologie ◽

10.1055/s-0033-1360992 ◽

2014 ◽

Vol 52 (01) ◽

Author(s):

A Kloos ◽

E Gürlevik ◽

N Woller ◽

CI Ureche ◽

MP Manns ◽

...

Keyword(s):

T Cell ◽

T Cell Responses ◽

Cd8 T Cell ◽

Cell Responses ◽

Oncolytic Adenoviruses

Download Full-text

P88 USAGE OF ADAPTER-MEDIATED RETARGETING OF ONCOLYTIC ADENOVIRUSES FACILITATES ANTIGEN-SPECIFIC CD8 T CELL RESPONSES AND LEADS TO REDUCED HEPATOTOXICITY IN MICE

Journal of Hepatology ◽

10.1016/s0168-8278(14)60251-8 ◽

2014 ◽

Vol 60 (1) ◽

pp. S95-S96

Author(s):

C.I. Ureche

Keyword(s):

T Cell ◽

T Cell Responses ◽

Cd8 T Cell ◽

Cell Responses ◽

Oncolytic Adenoviruses

Download Full-text

Review for "Fibroblast‐derived IL‐33 is dispensable for lymph node homeostasis but critical for CD8 T cell responses to acute and chronic viral infection"

10.1002/eji.201948413/v2/review1 ◽

2020 ◽

Keyword(s):

Lymph Node ◽

T Cell ◽

Viral Infection ◽

T Cell Responses ◽

Cd8 T Cell ◽

Chronic Viral Infection ◽

Cell Responses

Download Full-text

Review for "Fibroblast‐derived IL‐33 is dispensable for lymph node homeostasis but critical for CD8 T cell responses to acute and chronic viral infection"

10.1002/eji.201948413/v1/review1 ◽

2019 ◽

Author(s):

Ramon Arens

Keyword(s):

Lymph Node ◽

T Cell ◽

Viral Infection ◽

T Cell Responses ◽

Cd8 T Cell ◽

Chronic Viral Infection ◽

Cell Responses

Download Full-text

Development of an orthotopic HCC mouse model for analysis of tumor-specific CD8 T cell responses

Zeitschrift für Gastroenterologie ◽

10.1055/s-0033-1360959 ◽

2014 ◽

Vol 52 (01) ◽

Author(s):

D Ostroumov ◽

MP Manns ◽

S Kubicka ◽

F Kühnel ◽

T Wirth

Keyword(s):

T Cell ◽

Mouse Model ◽

T Cell Responses ◽

Cd8 T Cell ◽

Cell Responses

Download Full-text

Analysis of Successful Virus-Specific CD8+ T Cell Responses in acute HBV infection

Zeitschrift für Gastroenterologie ◽

10.1055/s-2006-931754 ◽

2006 ◽

Vol 44 (01) ◽

Author(s):

E Panther ◽

B Bengsch ◽

T Böttler ◽

N Nazarova ◽

HC Spangenberg ◽

...

Keyword(s):

T Cell ◽

T Cell Responses ◽

Cd8 T Cell ◽

Hbv Infection ◽

Cell Responses

Download Full-text

Peripheral CD8 T-Cell Responses to Apoptotic Cell Proteins and Peptides

Critical Reviews™ in Immunology ◽

10.1615/critrevimmunol.v27.i4.50 ◽

2007 ◽

Vol 27 (4) ◽

pp. 357-365 ◽

Cited By ~ 4

Author(s):

Yu Feng Peng ◽

Keith B. Elkon

Keyword(s):

T Cell ◽

Apoptotic Cell ◽

T Cell Responses ◽

Cd8 T Cell ◽

Cell Responses ◽

Proteins And Peptides

Download Full-text

Faculty Opinions recommendation of CD94-NKG2A receptors regulate antiviral CD8(+) T cell responses.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1004003.46504 ◽

2002 ◽

Author(s):

Nicole Suciu-Foca

Keyword(s):

T Cell ◽

T Cell Responses ◽

Cd8 T Cell ◽

Cell Responses

Download Full-text

Faculty Opinions recommendation of Cutting edge: recombinant adenoviruses induce CD8 T cell responses to an inserted protein whose expression is limited to nonimmune cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1002554.23004 ◽

2001 ◽

Author(s):

William Heath

Keyword(s):

T Cell ◽

T Cell Responses ◽

Cd8 T Cell ◽

Cutting Edge ◽

Cell Responses

Download Full-text

Faculty Opinions recommendation of IL-21 enhances and sustains CD8+ T cell responses to achieve durable tumor immunity: comparative evaluation of IL-2, IL-15, and IL-21.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1020664.236442 ◽

2004 ◽

Author(s):

Arthur Hurwitz

Keyword(s):

T Cell ◽

Tumor Immunity ◽

Comparative Evaluation ◽

T Cell Responses ◽

Cd8 T Cell ◽

Cell Responses

Download Full-text

Faculty Opinions recommendation of Durable protection of rhesus macaques immunized with a replicating adenovirus-SIV multigene prime/protein boost vaccine regimen against a second SIVmac251 rectal challenge: role of SIV-specific CD8+ T cell responses.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1047136.498191 ◽

2006 ◽

Author(s):

Kendall Smith

Keyword(s):

T Cell ◽

Rhesus Macaques ◽

T Cell Responses ◽

Cd8 T Cell ◽

Vaccine Regimen ◽

Cell Responses ◽

Protein Boost ◽

Boost Vaccine

Download Full-text