A Catalyzed Aerobic Intramolecular C–O Bond Formation: Facile Access to Ring-Fused Dihydrobenzoxazine Derivatives

Synthesis ◽  
2017 ◽  
Vol 49 (20) ◽  
pp. 4693-4697 ◽  
Author(s):  
Xiao-Jie Shang ◽  
Zhong-Quan Liu
Keyword(s):  
Free Radical ◽  
Bond Formation ◽  
Environmentally Friendly ◽  
Selective Functionalization ◽  
Environmentally Friendly Approach ◽  
Oxazine Derivatives

A catalyst comprising of catalytic cobalt(II) acetate/copper(II) acetate/dl-tyrosine with oxygen as the oxidant allows aerobic intramolecular C–O bond construction in [2-(pyrrolidin-1-yl)phenyl]methanol by free-radical promoted intramolecular selective functionalization of an (sp3)C–H bond by the alcohol, thus providing an environmentally friendly approach to 5H-benzo[d]pyrrolo[2,1-b][1,3]oxazine derivatives.

scholarly journals Copper-catalyzed C–C direct cross-coupling: an efficient approach to phenyl-2-(phenylthiophenyl)-methanones

RSC Advances ◽  
2017 ◽  
Vol 7 (33) ◽  
pp. 20123-20127 ◽  
Author(s):  
Qi Zhang ◽  
Wei Wang ◽  
Chong Gao ◽  
Rong-Rong Cai ◽  
Run-Sheng Xu
Keyword(s):  
Bond Formation ◽  
Coupling Reaction ◽  
Cross Coupling ◽  
Environmentally Friendly ◽  
Efficient Approach ◽  
Cross Coupling Reaction ◽  
Direct Cross ◽  
Environmentally Friendly Approach

An efficient copper-catalyzed C–C bond direct cross-coupling reaction has been developed. This new methodology provides an economical and environmentally friendly approach toward C(sp2)–C(sp2) bond formation.

Water-Mediated Strecker Reaction: An Efficient and Environmentally Friendly Approach for the Synthesis of α-Aminonitriles via a Three-Component Condensation

2010 ◽  
Vol 40 (23) ◽  
pp. 3544-3551 ◽  
Author(s):  
Samikannu Ramesh ◽  
Kulanthaivel Sivakumar ◽  
Chiradeep Panja ◽  
Pirama Nayagam Arunachalam ◽  
Appaswami Lalitha
Keyword(s):  
Environmentally Friendly ◽  
Strecker Reaction ◽  
Environmentally Friendly Approach

Efficient synthesis of glycosylamines in solventless conditions promoted by mechanical milling

RSC Advances ◽  
2014 ◽  
Vol 4 (68) ◽  
pp. 36350-36356 ◽  
Author(s):  
Cédric Epoune Lingome ◽  
Gwladys Pourceau ◽  
Virginie Gobert-Deveaux ◽  
Anne Wadouachi
Keyword(s):  
Mechanical Milling ◽  
Environmentally Friendly ◽  
Efficient Synthesis ◽  
Environmentally Friendly Approach

A mecanosynthesis of glycosylamines under solventless conditions was established. This environmentally friendly approach optimized with l-rhamnose, was investigated using a variety of amines and other carbohydrates.

Critical Review of Biotransformational Studies on Steroids by Using Culture of Cunninghamella blakesleeana

2021 ◽  
Vol 18 ◽  
Author(s):  
Azizuddin ◽  
Muhammad Iqbal ◽  
Syed Ghulam Musharraf
Keyword(s):  
Double Bond ◽  
Critical Review ◽  
Structural Modification ◽  
Bond Formation ◽  
Environmentally Friendly ◽  
Side Chain ◽  
Synthetic Compounds ◽  
Efficient Approach ◽  
Cunninghamella Blakesleeana ◽  
Different Strains

: For several decades, biotransformational studies on steroidal compounds have gained a lot of attention because it is an efficient approach for the structural modification of complicated natural or synthetic compounds with high regio-, chemo- and stereoselectivity at environmentally friendly conditions. This review summarizes the use of different strains of Cunninghamella blakesleeana for the biotransformation of sixteen steroids 1-16 into a variety of transformed products. The transformed products may be important as a drug or precursor for the production of important pharmaceuticals. The types of reactions performed by C. blakesleeana include hydroxylation, epoxidation, reduction, demethylation, oxidation, glycosidation, double bond formation, side-chain degradation, isomerisation and opening of an isoxazol ring, which would be difficult to produce by traditional synthesis.

Dirhodium(II)-Catalyzed Diamination Reaction via a Free Radical Pathway

2021 ◽  
Author(s):  
Zhiying Fan ◽  
Zhifan Wang ◽  
Ruoyi Shi ◽  
Yuanhua Wang
Keyword(s):  
Free Radical ◽  
Bond Formation ◽  
Mechanistic Study ◽  
Radical Mechanism ◽  
Free Radical Mechanism

Unlike C-N bond formation with classical dirhodium(II)-nitrenoids as the key intermediate, dirhodium(II)-catalyzed 1,2-and 1,3-diamination reactions are realized by a free radical mechanism. A mechanistic study revealed that the reactions undergo...

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