Generic versus Disease-specific Instruments in Quality-of-life Assessment of Chronic Obstructive Pulmonary Disease

2006 ◽  
Vol 45 (02) ◽  
pp. 211-215 ◽  
Author(s):  
V. Vondra ◽  
M. Malý
Keyword(s):  
Quality Of Life ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Well Being ◽  
Life Assessment ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Sf 36 ◽  
Disease Specific

Summary Objectives: Chronic respiratory diseases may alter a patient’s social life and well-being. Measures of health-related quality of life have been proven to bring complementary information to functional assessments. The aim of the study was to describe the questionnaires that are most frequently used to measure this subjective construct in patients with chronic obstructive pulmonary disease (COPD) and to compare the responses obtained via administering one generic (SF-36) and one disease-specific questionnaire (St. George’s Respiratory Questionnaire; SGRQ) to patients with COPD. Methods: One group of patients (46 individuals) was used to evaluate the questionnaire’s performance in repeated administrations under unchanged conditions (reproducibility) and to study the correlations of corresponding domains of respective questionnaires. Responsiveness of both questionnaires was tested on another group of 129 patients measured before and after the therapeutic stay at the spa. Methods of cor-relational analysis (Spearman, intraclass, and canonical correlation coefficients) as well as the Wilcoxon rank test were used for statistical analysis. Results: Both questionnaires seem to be comprehensive outcome measures for patients with COPD, but some particular areas may not be covered with the same intensity (e.g. emotional problems). Reproducibility of both questionnaires was good and only small non-significant shifts were seen, particularly in physical and social functioning domains. In repeated measurement, the SGRQ seemed to be slightly more responsive to change than the SF-36. Conclusions: The idea of using generic and disease-specific questionnaires together probably represents the best approach to this topic. It may improve our knowledge and explain better the relationship between disease-specific changes in patient status and both disease-specific treatment and general functional status.

scholarly journals Evaluation of the quality of life in patients with chronic obstructive pulmonary disease in combination with cardiovascular disease.

2017 ◽  
Vol 95 (7) ◽  
pp. 629-633
Author(s):  
A. A. Nizov ◽  
V. N. Abrosimov ◽  
Anna N. Vyunova ◽  
I. B. Ponomareva
Keyword(s):  
Quality Of Life ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Bodily Pain ◽  
Well Being ◽  
Role Playing ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Sf 36

This article reports the results of evaluation of the quality of life in patients with chronic obstructive pulmonary disease (COPD) and its combination with coronary heart disease (CHD) or essential hypertension (HD) based on the SF-36 questionnaire designed for the non-specific assessment of the patient's quality of life and widely used in clinical studies to characterize theirgeneral well-being and the degree of satisfaction with those aspects of human activity that affect health. SF-36 consists of 36 questions, grouped into eight scales: physical functioning, role-playing activity, bodily pain, general health, vitality, social functioning, emotional well-being and mental health. The scales are combined in such a way that the higher the value (from 0 to 100) the better results of evaluation based on a given scale. They were used to derive two parameters characterizing psychological and physical components of health.

Clustering effects of chronic obstructive pulmonary disease specific quality of life in hospitalized patients

Respirology ◽  
2003 ◽  
Vol 8 (3) ◽  
pp. 339-343 ◽  
Author(s):  
Adrian LOWE ◽  
Donald CAMPBELL ◽  
Pieter WALKER ◽  
Stephen FARISH ◽  
Bruce JACKSON ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Hospitalized Patients ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Disease Specific

scholarly journals The observational, cross sectional study to assess quality of life on patient suffering from chronic obstructive pulmonary disease in tertiary care hospital

2020 ◽  
Vol 9 (1) ◽  
pp. 162
Author(s):  
Kavita S. Joshi ◽  
Prasad R. Amrale ◽  
Sagar S. Ahire
Keyword(s):  
Quality Of Life ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Well Being ◽  
Health Improvement ◽  
Chronic Obstructive ◽  
Care Hospital ◽  
Obstructive Pulmonary Disease ◽  
The Impact

Background: Chronic obstructive pulmonary disease (COPD) patients often present considerable individual medical burden in their symptoms, limitations, and well-being that complicate medical treatment. Quality of life (QOL) is an important aspect for measuring the impact of chronic diseases. HRQOL measurement facilitates the evaluation of efficacy of medical interventions and also the detection of groups at risk of psychological or behavioural problems.Methods: COPD patient attending the OPD/IPD are screened as per inclusion and exclusion criteria. After obtaining a written informed consent of eligible patient, they were enrolled in the study. QOL of patient is assessed based on a set of questionnaire i.e. COPD Assessment Test™ (CAT). The questionnaire was translated to Hindi and Marathi. Socio demographic variable like age, sex, education occupation and income are also collected. All 8 questions related to health-improvement and management of COPD. CAT scores were given to each question according to the level of impact.Results: In the total score of CAT we observed that there were 2.04% patients with very good QOL, 25.51% with good QOL, 61.22% with moderate QOL and 11.22% with poor QOL.Conclusions: We conclude that the quality of life is moderate in larger number of patient’s population. The most affected domain was the patient’s energy level. The patients enrolled had COPD from long period of time which might have affected their answer because they have been habitual with the difficulties arising from COPD.

scholarly journals Impact of Frailty on Hippocampal Volume in Patients with Chronic Obstructive Pulmonary Disease

Biomedicines ◽  
2021 ◽  
Vol 9 (9) ◽  
pp. 1103
Author(s):  
Shun Takahashi ◽  
Tsunahiko Hirano ◽  
Kasumi Yasuda ◽  
Tomohiro Donishi ◽  
Kazuyoshi Suga ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Obstructive Pulmonary Disease ◽  
Depressive Symptoms ◽  
Pulmonary Disease ◽  
Hippocampal Volume ◽  
Life Assessment ◽  
World Health ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease

Brain frailty may be related to the pathophysiology of poor clinical outcomes in chronic obstructive pulmonary disease (COPD). This study examines the relationship between hippocampal subfield volumes and frailty and depressive symptoms, and their combined association with quality of life (QOL) in patients with COPD. The study involved 40 patients with COPD. Frailty, depressive symptoms and QOL were assessed using Kihon Checklist (KCL), Hospital Anxiety and Depression Scale (HADS), and World Health Organization Quality of Life Assessment (WHO/QOL-26). Anatomical MRI data were acquired, and volumes of the hippocampal subfields were obtained using FreeSurfer (version 6.0) (Harvard University, Boston, MA, USA). Statistically, HADS score had significant association with WHO/QOL-26 and KCL scores. KCL scores were significantly associated with volumes of left and right whole hippocampi, presubiculum and subiculum, but HADS score had no significant association with whole hippocampi or hippocampal subfield volumes. Meanwhile, WHO/QOL-26 score was significantly associated with volume of the left CA1. There was a significant association between frailty, depression, and QOL. Hippocampal pathology was related to frailty and, to some extent, with QOL in patients with COPD. Our results suggest the impact of frailty on hippocampal volume and their combined associations with poor QOL in COPD.

scholarly journals Relaxation Techniques for People with Chronic Obstructive Pulmonary Disease: A Systematic Review and a Meta-Analysis

2015 ◽  
Vol 2015 ◽  
pp. 1-22 ◽  
Author(s):  
Eleonora Volpato ◽  
Paolo Banfi ◽  
Sheena Michelle Rogers ◽  
Francesco Pagnini
Keyword(s):  
Quality Of Life ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Relaxation Training ◽  
Meta Analysis ◽  
Well Being ◽  
Chronic Obstructive ◽  
Relaxation Techniques ◽  
Obstructive Pulmonary Disease

Introduction. Chronic Obstructive Pulmonary Disease (COPD) people suffer from severe physical impairments, which often elicit significant psychological distress and impact their quality of life. This meta-analysis aimed to assess evidence from the scientific literature on the effects of relaxation techniques.Methods. We investigated 9 databases to select 25 RCTs. Studies included both inpatients and outpatients with COPD. Both respiratory and psychological outcomes were considered.Results. Relaxation techniques showed a little positive effect on the value of the percentage of predicted FEV1(d=0.20; 95% Cl: 0.40–−0.01) as well as a slight effect on levels of both the anxiety (d=0.26; 95% Cl: 0.42–0.10) and depression (d=0.33; 95% Cl: 0.53–0.13). The higher effect size was found in the quality of life value (d=0.38; 95% Cl: 0.51–0.24). The assessed quality of the studies, based on the PEDro Scale, was generally medium/high.Conclusion. Relaxation training can have a moderate impact on both psychological well-being and respiratory function, resulting in noticeable improvements in both. Although higher quality research is required, our results sustain the importance of relaxation techniques as a tool to manage COPD.

scholarly journals Haemoglobin as a biomarker for clinical outcomes in chronic obstructive pulmonary disease

2021 ◽  
pp. 00068-2021
Author(s):  
Aparna Balasubramanian ◽  
Robert J. Henderson ◽  
Nirupama Putcha ◽  
Ashraf Fawzy ◽  
Sarath Raju ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Obstructive Pulmonary Disease ◽  
Physical Health ◽  
Pulmonary Disease ◽  
Functional Performance ◽  
Chronic Obstructive ◽  
Diffusing Capacity ◽  
Obstructive Pulmonary Disease ◽  
Sf 36

In Chronic Obstructive Pulmonary Disease (COPD), anaemia is associated with increased morbidity, but the relationship between haemoglobin over its entire observed range and morbidity is poorly understood. Such an understanding could guide future therapeutic targeting of haemoglobin in COPD management. Leveraging the COPDGene® study, we conducted a cross-sectional analysis of haemoglobin from COPD participants, examining symptoms, quality of life, functional performance, and acute exacerbations of COPD (AECOPD). Haemoglobin was analysed both as a continuous variable and categorized into anaemia, normal haemoglobin, and polycythaemia groups. Fractional polynomial modelling was used for continuous analyses; categorical models were multivariable linear or negative binomial regressions. Covariates included demographics, comorbidities, emphysema, diffusing capacity, and airflow obstruction. From 2539 participants, 366(14%) were identified as anaemic and 125(5%) as polycythaemic. Compared to normal haemoglobin, anaemia was significantly associated with increased symptoms (CAT score: p=0.006, mMRC: p=0.001), worse quality of life (SGRQ score: p<0.001, SF-36 General Health: p=0.002, SF-36 Physical Health: p<0.001), decreased functional performance (6MWD: p<0.001), and severe AECOPD (p=0.01), while polycythaemia was not. Continuous models however demonstrated increased morbidity at both ends of the haemoglobin distribution (p<0.01 for mMRC, SGRQ, SF-36 Physical Health, 6MWD, and severe AECOPD). Evaluating interactions, both diffusing capacity and haemoglobin were independently associated with morbidity. We present novel findings that haemoglobin derangements towards either extreme of the observed range are associated with increased morbidity in COPD. Further investigation is necessary to determine whether haemoglobin derangement drives morbidity or merely reflects systemic inflammation and whether correcting haemoglobin towards the normal range improves morbidity.

scholarly journals COMPARATIVE STUDY OF THE IMPACT OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE ON THE QUALITY OF LIFE OF PATIENTS WITH PULMONARY TUBERCULOSIS BASED ON THE MOS SF-36 QUESTIONNAIRE

2021 ◽  
Vol 14 (3) ◽  
pp. 63-69
Author(s):  
MARAT F. YAUSHEV ◽  
◽  
ALEXEY P. ALEXEEV ◽  
ILGIZYAR F. MAKHMUTOV ◽  
BORIS M. PETROV ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Tuberculosis ◽  
Pulmonary Disease ◽  
Negative Impact ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Sf 36 ◽  
The Impact

Pulmonary tuberculosis (TBL), as well as chronic obstructive pulmonary disease (COPD), have a diverse negative impact on the quality of life (QOL) of patients. In this regard, a detailed study of the quality of life of patients with pulmonary tuberculosis in combination with chronic obstructive pulmonary disease retains its importance and relevance.

scholarly journals A STUDY ON THE EFFECT OF EXACERBATIONS ON THE QUALITY OF LIFE OF PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

2020 ◽  
Author(s):  
PUSHPAVALLI KOTHA ◽  
Naga Vamsi Krishna Vasabhakthula ◽  
Christine Undurthi ◽  
Siva Ganga M
Keyword(s):  
Quality Of Life ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Well Being ◽  
Self Report ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Grade 3 ◽  
Study Participants

Aim:  The main aim of this study is to evaluate the effect of exacerbations on the quality of life of the patients with chronic obstructive pulmonary disease. Materials and Methods: Patients of both the genders and with an age of above 18 years of patients who were diagnosed with COPD were included in this prospective study. Modified British Medical Research Council (m-MRC) Dyspnoea Scale was used to establish functional impairment due to shortness of breath in the study participants. Saint George's Respiratory Questionnaire (SGRQ) was also used to assess the patient’s overall health and quality of life-based on self-report. Results: Among the 110 study participants, 87.3% were males and 12.7% were females. It was observed that majority of the patients were in the age group 51-60 years (43.6%). The most frequently observed co-morbidities were hypertension (22.7%) followed by diabetes mellitus (19.1%). Most of the patients were observed to be with m-MRC grade-3 (42.7%) followed by m-MRC garde-2 (39.1%). The SGRQ score was observed to be increased with increase in the frequency of exacerbations. Conclusion: Clinical Pharmacist should take the responsibility in providing effective evidence based therapeutic recommendations for the better management and well being of the COPD patients.

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