Towards novel imaging Biomarkers for PD: characterising the dynamic pattern of regional metabolism in idiopathic REM-Sleep-Behaviour-Disorders

2019 ◽  
Author(s):  
I Alberts ◽  
W Ping ◽  
H Xianhua ◽  
I Yakushev ◽  
J Wang ◽  
...  
2008 ◽  
Vol 9 (4) ◽  
pp. 343-351 ◽  
Author(s):  
Michele Terzaghi ◽  
Elena Sinforiani ◽  
Chiara Zucchella ◽  
Elena Zambrelli ◽  
Chiara Pasotti ◽  
...  

2016 ◽  
Vol 22 ◽  
pp. S69-S72 ◽  
Author(s):  
Luigi Ferini-Strambi ◽  
Fabrizio Rinaldi ◽  
Enrico Giora ◽  
Sara Marelli ◽  
Andrea Galbiati

2009 ◽  
Vol 61 (3) ◽  
pp. 164-170 ◽  
Author(s):  
Asako Yoritaka ◽  
Hideki Ohizumi ◽  
Shigeki Tanaka ◽  
Nobutaka Hattori

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Jitka Bušková ◽  
Eva Miletínová ◽  
Monika Kliková ◽  
Martin Bareš ◽  
Tomáš Novák ◽  
...  

Abstract Background Isolated REM sleep without atonia (RSWA) as a main polysomnograhic feature of REM sleep behaviour disorder (RBD) is thought to be a prodromal or subclinical state of the disease. RSWA/RBD occurence in psychiatric population is much more frequent than in general population but its associated factors are still not known. Methods We invited 88 psychiatry in-patients to undervent video-polysomnography. The visual scoring was focused on RSWA in submentales and flexores digitales superficiales muscles. This parametr was subsequently correlated mainly with age/gender, their medication and mental status. Results The RWSA was mostly still in normal range despite the fact, that selected psychiatry patients (≤ 50 years) were taking several classes of psychoactive medication. 3,6% had convincingly RBD, although 35.7% reported rare lifetime occurence of dream-enacting behaviour and 62.8% sporadic nightmares. We found correlation between RSWA and SNRI medication class (p = 0.015), specifically venlafaxine (p = 0.029) as well as quetiapine (p = 0.030). Another significant associated factors were current anxiety (p < 0.001) and depressive symptoms (p = 0.05), but we found no relation between RSWA and given diagnosis. Conlucions Isolated RSWA in younger psychiatry patients might be a result of multiple factors, including medication and current mental status but these factors are in most cases not sufficient to manifest RBD.


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