The course of spontaneous subarachnoid hemorrhage: Risk factors for recurrence of cerebral vasospasm and related infarction after transluminal balloon angioplasty as a local treatment option

2020 ◽  
Author(s):  
A Neumann ◽  
J Küchler ◽  
T Boppel ◽  
J Leppert ◽  
C Ditz ◽  
...  
Open Medicine ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. 598-604
Author(s):  
Valentina Opancina ◽  
Snezana Lukic ◽  
Slobodan Jankovic ◽  
Radisa Vojinovic ◽  
Milan Mijailovic

AbstractIntroductionAneurysmal subarachnoid hemorrhage is a type of spontaneous hemorrhagic stroke, which is caused by a ruptured cerebral aneurysm. Cerebral vasospasm (CVS) is the most grievous complication of subarachnoid hemorrhage (SAH). The aim of this study was to examine the risk factors that influence the onset of CVS that develops after endovascular coil embolization of a ruptured aneurysm.Materials and methodsThe study was designed as a cross-sectional study. The patients included in the study were 18 or more years of age, admitted within a period of 24 h of symptom onset, diagnosed and treated at a university medical center in Serbia during a 5-year period.ResultsOur study showed that the maximum recorded international normalized ratio (INR) values in patients who were not receiving anticoagulant therapy and the maximum recorded white blood cells (WBCs) were strongly associated with cerebrovascular spasm, increasing its chances 4.4 and 8.4 times with an increase of each integer of the INR value and 1,000 WBCs, respectively.ConclusionsSAH after the rupture of cerebral aneurysms creates an endocranial inflammatory state whose intensity is probably directly related to the occurrence of vasospasm and its adverse consequences.


2010 ◽  
Vol 20 (4) ◽  
pp. 258-262
Author(s):  
Guang Jian Liu ◽  
Yun Fu Wang ◽  
Yong Liu ◽  
Guo Hou He ◽  
Jun Chen ◽  
...  

CHEST Journal ◽  
2006 ◽  
Vol 130 (4) ◽  
pp. 216S
Author(s):  
Dipak Chandy ◽  
Roger Sy ◽  
Wilbert Aronow ◽  
George Maguire ◽  
Wei-Nchih Lee

Stroke ◽  
2010 ◽  
Vol 41 (10) ◽  
pp. 2353-2357 ◽  
Author(s):  
Peter Lackner ◽  
Anelia Dietmann ◽  
Ronny Beer ◽  
Marlene Fischer ◽  
Gregor Broessner ◽  
...  

2016 ◽  
Vol 25 (2) ◽  
pp. 243-249 ◽  
Author(s):  
Hongsheng Liang ◽  
Liyang Zhang ◽  
Aili Gao ◽  
Yonghua Li ◽  
Zhenfeng Jiang ◽  
...  

1996 ◽  
Vol 84 (1) ◽  
pp. 35-42 ◽  
Author(s):  
Yukihiko Fujii ◽  
Shigekazu Takeuchi ◽  
Osamu Sasaki ◽  
Takashi Minakawa ◽  
Tetsuo Koike ◽  
...  

✓ To determine the incidence of, and risk factors for, the occurrence of rebleeding between admission and early operation (ultra-early rebleeding) in patients with spontaneous subarachnoid hemorrhage (SAH), the authors reviewed the cases of 179 patients admitted within 24 hours after their last attack of SAH. Thirty-one (17.3%) of these patients had ultra-early rebleeding despite scheduling of early operation (within 24 hours after admission). The incidence of rebleeding significantly decreased as the time interval between the last attack and admission increased. Patients with rebleeding before admission, high systolic blood pressure, intracerebral or intraventricular hematoma, those in poor neurological condition on admission, and those who underwent angiography within 6 hours of the last SAH were significantly more likely to have ultra-early rebleeding than those without these factors. The incidence of rebleeding also significantly increased as levels of enhancement of platelet sensitivity and thrombin—antithrombin complex increased. Multivariate analysis revealed that the following three factors were independently associated with ultra-early rebleeding: the level of enhancement of platelet sensitivity; the time interval between the last attack and admission; and the level of thrombin—antithrombin complex. On the basis of these findings, the authors suggest that many of the risk factors for ultra-early rebleeding are interrelated. A particularly high risk of ultra-early rebleeding was observed in those patients 1) who had platelet hypoaggregability; 2) who were admitted shortly after their last SAH; and 3) whose thrombin—antithrombin complex levels were extremely high and were thus in severe clinical condition.


Neurology ◽  
2007 ◽  
Vol 68 (13) ◽  
pp. 1013-1019 ◽  
Author(s):  
A. Fernandez ◽  
J. M. Schmidt ◽  
J. Claassen ◽  
M. Pavlicova ◽  
D. Huddleston ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document