scholarly journals Performance Evaluation of High-Resolution Ultrasound versus Magnetic Resonance Imaging in Diagnosing Peripheral Nerve Pathologies

2021 ◽  
Vol 31 (01) ◽  
pp. 043-048
Author(s):  
Neha Nischal ◽  
Saurabh Gupta ◽  
Kanhaiya Lal ◽  
Jatinder Pal Singh
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Peripheral Nerve ◽  
Confidence Level ◽  
Predictive Value ◽  
Imaging Modality ◽  
Image Interpretation ◽  
Resonance Imaging ◽  
Magnetic Resonance Neurography

Abstract Background High-resolution ultrasound (HRUS) and magnetic resonance neurography (MRN) are considered complementary to clinical and neurophysiological assessment for neuropathies. Aims The aim of our study was to compare the accuracy of HRUS and MRN for detecting various peripheral nerve pathologies, to choose the correct investigation to facilitate prompt patient management. Materials and Methods This prospective study was done using HRUS with 14 MHz linear-transducer and 3 or 1.5T MR in cases referred for the assessment of peripheral nerve pathologies. Image interpretation was done using a scoring system (score 0–3 confidence level) to assess for nerve continuity/discontinuity, increased nerve signal/edema, fascicular change, caliber change, and neuroma/mass lesion. We determined the accuracy, sensitivity, and specificity of these modalities compared with the diagnostic standard determined by surgical and/or histopathological, if not performed then clinical and/or electrodiagnostic evaluation. Results The overall accuracy of MRN was 89.3% (specificity: 66.6%, sensitivity: 92.6%, negative predictive value [NPV]: 57.1%, positive predictive value [PPV]: 95%) and that of HRUS was 82.9% (specificity: 100%, sensitivity: 80.4%, NPV: 42.8, PPV: 100). The confidence level for detecting nerve discontinuity and change in nerve caliber was found to be higher on ultrasonography than magnetic resonance imaging (MRI) (100 vs. 70% and 100 vs. 50%, respectively). Pathology of submillimeter caliber nerves was accurately detected by HRUS and these could not be well-visualized on MRI. Conclusion HRUS is a powerful tool that may be used as the first-line imaging modality for the evaluation of peripheral nerve pathologies, and a better means of evaluation of peripheral nerves with submillimeter caliber.

Functional information from magnetic resonance imaging

1995 ◽  
Vol 53 ◽  
pp. 84-85
Author(s):  
Alan P. Koretsky ◽  
Afonso Costa e Silva ◽  
Yi-Jen Lin
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Cancer Biology ◽  
Imaging Modality ◽  
Magnetic Resonance Images ◽  
Great Success ◽  
Functional Information ◽  
Resonance Imaging ◽  
High Resolution Mri

Magnetic resonance imaging (MRI) has become established as an important imaging modality for the clinical management of disease. This is primarily due to the great tissue contrast inherent in magnetic resonance images of normal and diseased organs. Due to the wide availability of high field magnets and the ability to generate large and rapidly switched magnetic field gradients there is growing interest in applying high resolution MRI to obtain microscopic information. This symposium on MRI microscopy highlights new developments that are leading to increased resolution. The application of high resolution MRI to significant problems in developmental biology and cancer biology will illustrate the potential of these techniques.In combination with a growing interest in obtaining high resolution MRI there is also a growing interest in obtaining functional information from MRI. The great success of MRI in clinical applications is due to the inherent contrast obtained from different tissues leading to anatomical information.

High-Resolution Magnetic Resonance Imaging of the Human Median Nerve

2004 ◽  
Vol 18 (2) ◽  
pp. 80-87 ◽  
Author(s):  
Archie Heddings ◽  
Mehmet Bilgen ◽  
Randolph Nudo ◽  
Bruce Toby ◽  
Terence McIff ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Peripheral Nerve ◽  
Median Nerve ◽  
Ex Vivo ◽  
Imaging Techniques ◽  
Proton Density ◽  
Resonance Imaging ◽  
Imaging Protocols

Objectives. It is widely accepted that peripheral nerve repairs performed within 6 weeks of injury have much better outcomes than those performed at later dates. However, there is no diagnostic technique that can determine if a traumatic peripheral nerve injury requires surgical intervention in the early postinjury phase. The objective of this article was to determine whether novel, noninvasive magnetic resonance imaging techniques could demonstrate the microstructure of human peripheral nerves that is necessary for determining prognosis and determining if surgery is indicated following traumatic injury. Methods. Ex vivo magnetic resonance imaging protocols were developed on a 9.4-T research scanner using spin-echo proton density and gradient-echo imaging sequences and a specially designed, inductively coupled radio frequency coil. These imaging protocols were applied to in situ imaging of the human median nerve in 4 fresh-frozen cadaver arms. Results. Noninvasive high-resolution images of the human median nerve were obtained. Structures in the nerve that were observed included fascicles, interfascicular epineurium, perineurium, and intrafascicular septations. Conclusion. Application of these imaging techniques to clinical scanners could provide physicians with a tool that is capable of grading the severity of nerve injuries and providing indications for surgery in the early postinjury phase.

scholarly journals Comparison of micro-ultrasound and multiparametric magnetic resonance imaging for prostate cancer: A multicenter, prospective analysis

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Laurence Klotz ◽  
Giovanni Lughezzani ◽  
Davide Maffei ◽  
Andrea Sanchez ◽  
Jose Gregorio Pereira ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Prostate Cancer ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Predictive Value ◽  
Low Cost ◽  
Resonance Imaging ◽  
Multiparametric Magnetic Resonance Imaging ◽  
Clinically Significant ◽  
Software Fusion

Introduction: High-resolution micro-ultrasound has the capability of imaging prostate cancer based on detecting alterations in ductal anatomy, analogous to multiparametric magnetic resonance imaging (mpMRI). This technology has the potential advantages of relatively low cost, simplicity, and accessibility compared to mpMRI. This multicenter, prospective registry aims to compare the sensitivity, specificity, negative predictive value (NPV), and positive predictive value (PPV) of mpMRI with high-resolution micro-ultrasound imaging for the detection of clinically significant prostate cancer. Methods: We included 1040 subjects at 11 sites in seven countries who had prior mpMRI and underwent ExactVu micro-ultrasound-guided biopsy. Biopsies were taken from both mpMRI targets (PI-RADS >3 and micro-ultrasound targets (PRIMUS >3). Systematic biopsies (up to 14 cores) were also performed. Various strategies were used for mpMRI target sampling, including cognitive fusion with micro-ultrasound, separate software-fusion systems, and software-fusion using the micro-ultrasound FusionVu system. Clinically significant cancer was those with Gleason grade group ≥2. Results: Overall, 39.5% were positive for clinically significant prostate cancer. Micro-ultrasound and mpMRI sensitivity was 94% vs. 90%, respectively (p=0.03), and NPV was 85% vs. 77%, respectively. Specificities of micro-ultrasound and MRI were both 22%, with similar PPV (44% vs. 43%). This represents the initial experience with the technology at most of the participating sites and, therefore, incorporates a learning curve. Number of cores, diagnostic strategy, blinding to MRI results, and experience varied between sites. Conclusions: In this initial multicenter registry, micro-ultrasound had comparable or higher sensitivity for clinically significant prostate cancer compared to mpMRI, with similar specificity. Micro-ultrasound is a low-cost, single-session option for prostate screening and targeted biopsy. Further larger-scale studies are required for validation of these findings.

The Diagnostic Accuracy of Magnetic Resonance Imaging and Ultrasonography in Gluteal Tendon Tears -A Systematic Review

2011 ◽  
Vol 21 (6) ◽  
pp. 637-645 ◽  
Author(s):  
Daniel J. Westacott ◽  
Jonathon I. Minns ◽  
Pedro Foguet
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Positive Predictive Value ◽  
Predictive Value ◽  
Imaging Modality ◽  
High Signal ◽  
Diagnostic Strategy ◽  
Resonance Imaging ◽  
Trochanteric Bursitis ◽  
Tendon Tears

Gluteal tendon tears are one of the many pathologies causing pain around the greater trochanter that are often labelled as trochanteric bursitis. We systematically reviewed the peer-reviewed literature to establish the accuracy of magnetic resonance imaging and ultrasonography in the diagnosis of gluteal tendon tears in patients with persistent lateral hip pain or Greater Trochanteric Pain Syndrome (GTPS). 7 studies met the inclusion criteria, comparing either imaging modality with a reference standard of surgical findings. Included studies were assessed for methodological quality using the QUADAS checklist. MRI had sensitivity of 33–100%, specificity of 92–100%, positive predictive value of 71–100% and negative predictive value of 50%. False-positives were common. High signal located superior to the trochanter had a stronger association with tears. Ultrasonography had a sensitivity of 79–100% and positive predictive value of 95–100%. The amount and quality of literature on the subject is limited and further well-designed studies are required to establish the optimum diagnostic strategy in this condition. Ultrasonography may prove to be the investigation of choice, despite requiring a skilled practitioner. The orthopaedic surgeon should liaise with an experienced musculoskeletal radiologist to best investigate and diagnose gluteal tendon tears in the clinical picture of GTPS.

MRI vs. High-Resolution CT Scanning: Evaluation of the Anterior Skull Base

1987 ◽  
Vol 96 (3) ◽  
pp. 260-267 ◽  
Author(s):  
Paul A. Levine ◽  
Michael R. Paling ◽  
William C. Back ◽  
Robert W. Cantrell
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
High Resolution ◽  
Head And Neck ◽  
Malignant Tumors ◽  
Imaging Modality ◽  
Ct Scanning ◽  
The United States ◽  
Resonance Imaging ◽  
High Resolution Ct

While magnetic resonance imaging (MRI) is no longer a tool of the future, its availability is limited. Most hospitals still use high-resolution computed tomography (CT) scanning as their major imaging modality. Although numerous articles point to the improved diagnostic uses of MRI—as compared to high-resolution CT—a change from high-resolution CT scanning to MRI scanning throughout the United States would cost billions of dollars. We should, therefore, delineate those clinical situations in which magnetic resonance imaging is distinctly superior to high-resolution CT scanning. It is already an accepted fact that MRI provides improved imaging of the central nervous system, but, while recent articles maintain the superiority of MRI head and neck imaging, the advantages to the clinician are less clear. We present representative cases of large malignant tumors of the frontal, ethmoid, and sphenoid sinuses, in which the full extent of the disease which involved intracranial structures and the orbit was better defined on the MRI scan than it was on the high-resolution CT scan. Decisions concerning the involvement of the infratemporal fossa, the cavernous sinus, the optic chiasm, the pituitary, and the frontal lobes were more easily made when based upon magnetic resonance imaging, while the tumor involvement as evaluated by CT scanning was much less clear. Establishment of the problem regions of the head and neck—when magnetic resonance imaging is superior to high-resolution CT scanning—will assist in identification of the true need for this tool in the practice of the otolaryngologist—head and neck surgeon.

scholarly journals 1.5-Tesla Multiparametric-Magnetic Resonance Imaging for the detection of clinically significant prostate cancer

2017 ◽  
Vol 90 (1) ◽  
pp. 40-48
Author(s):  
Cristian Popita ◽  
Anca Raluca Popita ◽  
Adela Sitar-Taut ◽  
Bogdan Petrut ◽  
Bogdan Fetica ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Prostate Cancer ◽  
Magnetic Resonance ◽  
Negative Predictive Value ◽  
Predictive Value ◽  
Imaging Modality ◽  
High Sensitivity ◽  
Resonance Imaging ◽  
Multiparametric Magnetic Resonance Imaging ◽  
Clinically Significant

Background and aims. Multiparametric-magnetic resonance imaging (mp-MRI) is the main imaging modality used for prostate cancer detection. The aim of this study is to evaluate the diagnostic performance of mp-MRI at 1.5-Tesla (1.5-T) for the detection of clinically significant prostate cancer.Methods. In this ethical board approved prospective study, 39 patients with suspected prostate cancer were included. Patients with a history of positive prostate biopsy and patients treated for prostate cancer were excluded. All patients were examined at 1.5-T MRI, before standard transrectal ultrasonography–guided biopsy.Results. The overall sensitivity, specificity, positive predictive value and negative predictive value for mp-MRI were 100%, 73.68%, 80% and 100%, respectively.Conclusion. Our results showed that 1.5 T mp-MRI has a high sensitivity for detection of clinically significant prostate cancer and high negative predictive value in order to rule out significant disease.

scholarly journals ACOUSTIC NEUROMA;

2019 ◽  
Vol 26 (04) ◽  
Author(s):  
Nazish Hameed ◽  
Muhammad Tahir ◽  
Noureen Jahangir ◽  
Hassan Bukhari ◽  
Hira Bukhari
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Diagnostic Accuracy ◽  
Acoustic Neuroma ◽  
Predictive Value ◽  
Gold Standard ◽  
Imaging Modality ◽  
Whole Body ◽  
Resonance Imaging ◽  
Cross Sectional Survey

Objectives: To determine the diagnostic accuracy of magnetic resonance imaging in the detection of acoustic neuroma taking histopathology as gold standard. Study Design: Cross-sectional survey. Setting: This study was carried out at the Department of Diagnostic Radiology, Lahore General Hospital, Lahore. Duration of Study with Dates: Study was completed in six months after approval of synopsis from 14-07-2009 to 14-01-2010. Subjects & Methods: This study comprised of 55 patients with clinical suspicion acoustic neuroma. Magnetic resonance imaging on a 1.5-T Philips whole body magnetic resonance system was performed. The cases were operated and histopathological results were recorded. The results of magnetic resonance imaging and histopathology were compared taking histopathology as gold standard. Results: Out of 55 patients, 43 patients (78.2%) had acoustic neuroma on magnetic resonance imaging. After comparison of results of magnetic resonance imaging with histopathology, the sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of magnetic resonance imaging were 97.7%, 91.7%, 97.7%, 91.7% and 96.4% respectively. Conclusion: Magnetic resonance imaging is a highly accurate, non-invasive, safe and convenient imaging modality for the evaluation of acoustic neuromas and is valuable for guiding surgical biopsies thereby decreasing unnecessary intervention. It allows detection of small tumours which is very useful in tumour characterization and plays an integral role in early detection, planning management and estimating patient’s prognosis.

scholarly journals The diagnostic value of digital breast tomosynthesis with complementary ultrasound in comparison with magnetic resonance imaging in assessment of postoperative changes and locoregional recurrence of breast cancer

2022 ◽  
Vol 53 (1) ◽  
Author(s):  
Mai M. K. Barakat ◽  
Eman K. A. E. Mohamed ◽  
Lobna A. E. Habib ◽  
Mortada Elsayed Ahmed
Keyword(s):  
Breast Cancer ◽  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Predictive Value ◽  
Locoregional Recurrence ◽  
Imaging Modality ◽  
Digital Breast Tomosynthesis ◽  
Resonance Imaging ◽  
Breast Tomosynthesis ◽  
Postoperative Changes

Abstract Background Digital breast tomosynthesis with complementary ultrasound is a powerful imaging modality in detection of breast cancer. Magnetic resonance imaging has many limitations due to its low specificity multiple pitfalls especially signal-to-noise ratio, as well as the spatial resolution. Our purpose of the study is to evaluate the role of digital breast tomosynthesis with complementary ultrasound compared to magnetic resonance imaging in the assessment of postoperative changes and locoregional recurrence of breast cancer. Results Our prospective study included thirty women who underwent conservative breast surgery. Digital breast tomosynthesis with complementary ultrasound revealed greater specificity (95.2%) than Magnetic resonance imaging (90.5%) in the detection of locoregional recurrence of breast cancer. On the other hand, it revealed the same sensitivity (88.9%). Subsequently, digital breast tomosynthesis with complementary ultrasound showed higher accuracy (93.3%) and higher positive predictive value (88.9%) than magnetic resonance imaging (90%), (80%), respectively. However, both of them revealed a comparable negative predictive value (95%). Conclusion Digital breast tomosynthesis with complementary ultrasound is a powerful imaging modality that can be used to detect any recurrence in patients who are surgically treated for breast cancer with higher specificity, accuracy than magnetic resonance imaging. Additionally, the use of these modalities enhances the diagnosis of surgically treated breast cancer for early detection of recurrence.

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