The impact of intrauterine growth retardation on glomerular filtration rate

2006 ◽  
Vol 210 (S 5) ◽  
Author(s):  
S Vanhaesebrouck ◽  
C Vanhole ◽  
F de Zegher ◽  
K Allegaert
2011 ◽  
Vol 6 (9) ◽  
pp. 2150-2156 ◽  
Author(s):  
Christine A. White ◽  
Andrew D. Rule ◽  
Christine P. Collier ◽  
Ayub Akbari ◽  
John C. Lieske ◽  
...  

2021 ◽  
Author(s):  
Mônica Rika Nakamura ◽  
Lúcio R. Requião-Moura ◽  
Roberto Mayer Gallo ◽  
Camila Botelho ◽  
Júlia Taddeo ◽  
...  

Abstract Due to the high costs, the strategy to reduce the impact of cytomegalovirus (CMV) after kidney transplant (KT) involves preemptive treatment in low and middle-income countries. Thus, this retrospective cohort study compared the performance of antigenemia transitioned to quantitative nucleic acid amplification testing, RT-PCR, in KT recipients receiving preemptive treatment as a strategy to prevent CMV infection. Between 2016 and 2018, 363 patients were enrolled and received preemptive treatment based on antigenemia (n=177) or RT-PCR (n=186). The primary outcome was CMV infection or disease. There were no differences in one-year cumulative incidence of CMV-related events (50.8% vs. 44.1%, P=0.20), neither in time to diagnosis (47.0 vs. 47.0 days) among patients conducted by antigenemia vs. RT-PCR, respectively. The length of CMV first treatment was longer with RT-PCR (20.0 vs. 27.5 days, P<0.001), while the rate of retreatment was not different (14.7% vs. 11.8%, P=0.48). In the Cox regression, the variables associated with CMV-related events were acute rejection within 30 days (HR=2.05, p=0.01) and 30-day glomerular filtration rate (HR=0.98, p<0.001). In conclusion, acute rejection and glomerular filtration rate are risk factors for CMV infection and disease, showing comparable performance in the impact of CMV-related events between antigenemia and RT-PCR for preemptive treatment.


Epidemiology ◽  
2007 ◽  
Vol 18 (Suppl) ◽  
pp. S197
Author(s):  
M Brauer ◽  
C Lencar ◽  
L Tamburic ◽  
J Marshall ◽  
C Karr ◽  
...  

2008 ◽  
Vol 247 (3) ◽  
pp. 524-529 ◽  
Author(s):  
Anthony L. Estrera ◽  
Charles C. Miller ◽  
Jaswanth Madisetty ◽  
Sebastian Bourgeois ◽  
Ali Azizzadeh ◽  
...  

Author(s):  
Anna L Barton ◽  
Angela S Mallard ◽  
Anthea Patterson ◽  
Nicola Thomas ◽  
Stephen Dickinson ◽  
...  

Introduction The ASSIST-CKD project is a national quality improvement programme, aiming to decrease the number of patients presenting late to renal services by enabling laboratories to review up to five years of estimated glomerular filtration rate results graphically and report deteriorating patients to their general practitioner. Aim To assess the impact of the project on the laboratory, and of patient reporting on general practitioner management and the local renal service. Method Each week two searches were performed (Search A: maximum age 65 years, maximum eGFR 50 ml/min/1.73 m2 and Search B: Age 66–120 years, maximum eGFR 40 ml/min/1.73 m2) on patients with an estimated glomerular filtration rate requested by their general practitioner within the previous seven days. Patients showing deterioration in estimated glomerular filtration rate had a printed graph sent to their general practitioner. Feedback on the graphs and their impact on patient management were obtained from the general practitioners via a questionnaire. Results A median of 37 patients/week were listed for review for Search A, with 32% reported; and Search B a median of 227 patients/week listed, 32% reported. General practitioner surgery questionnaires (29) showed the reports were well received. Of general practitioners responding to the questionnaire, 67% had reviewed a patient earlier than intended, 54% had reviewed local guidance, 48% had emailed the renal team and 48% had referred a patient on receipt of a graph; 34% had shown a graph to their patients, of whom 70% found that useful. Conclusion There is some evidence that ASSIST-CKD reporting has enhanced patient care; however, further long-term assessment is still required.


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