In-vivo microvascular imaging of early squamous-cell cancer of the esophagus by confocal laser endomicroscopy

Endoscopy ◽  
2007 ◽  
Vol 39 (04) ◽  
pp. 366-368 ◽  
Author(s):  
K. Deinert ◽  
R. Kiesslich ◽  
M. Vieth ◽  
M. Neurath ◽  
H. Neuhaus
2007 ◽  
Vol 65 (5) ◽  
pp. AB355
Author(s):  
Katja Deinert ◽  
Michael Vieth ◽  
Peter Charton ◽  
Brigitte Schumacher ◽  
Manfred Stolte ◽  
...  

2007 ◽  
Vol 65 (5) ◽  
pp. AB346 ◽  
Author(s):  
Oliver Pech ◽  
Thomas Rabenstein ◽  
Hendrik Manner ◽  
Maria C. Petrone ◽  
Juergen Pohl ◽  
...  

2007 ◽  
Vol 83 (2) ◽  
pp. 139-147 ◽  
Author(s):  
Shaleen Kumar ◽  
Kislay Dimri ◽  
Rohini Khurana ◽  
Neeraj Rastogi ◽  
Koilpillai Joseph Maria Das ◽  
...  

2020 ◽  
Author(s):  
Tingting Lu ◽  
Ying Yang ◽  
Ziming Li ◽  
Shun Lu

Abstract Background: Emerging evidence reveals that microRNAs (miRNAs) play a crucial role in tumor progression, but the underlying mechanism of microRNAs in lung squamous cell cancer (LSCC) remains unclear. Method : Western-blotting and quantitative real-time PCR (q-PCR) were carried out to detect mRNA and protein expression. Cell proliferation was evaluated by Cell Counting Kit-8 (CCK-8), colony-forming assay or sphere-forming assay, respectively. Results: MiR-214-3p was markedly de-regulated in LSCC tissues and was inversely related to the level of Yes-associated protein1 (YAP1), which is the core transcription regulator of the Hippo signaling pathway. Kaplan-Meier survival curves illustrated that patients with high miR-214-3p expression demonstrated more favorable clinical outcomes. MiR-214-3p overexpression (OE) repressed proliferation and cancer stem-like cells (CSCs) properties in vitro and in vivo xenograft mouse model. Mechanistically, luciferase activity assay revealed that miR-214-3p directly targets YAP1 by specifically binding on the 3’ UTR of YAP1. Conclusion: MiR-214-3p plays a pivotal role in CSCs properties by targeting YAP1, which provides a potential treatment strategy for LSCC patients.


2020 ◽  
Vol 30 (6) ◽  
pp. 3455-3461
Author(s):  
Jinrong Qu ◽  
Zhaoqi Wang ◽  
Jianjun Qin ◽  
Hongkai Zhang ◽  
Yan Zhao ◽  
...  

2001 ◽  
Vol 59 (2) ◽  
pp. 195-201 ◽  
Author(s):  
Corinne Delcambre ◽  
Jacques Henry Jacob ◽  
Didier Pottier ◽  
Marc Gignoux ◽  
Jean Michel Ollivier ◽  
...  

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