An Association Between Optic Glioma and Other Tumours of the Central Nervous System in Neurofibromatosis Type 1

1997 ◽  
Vol 28 (02) ◽  
pp. 131-132 ◽  
Author(s):  
J. Friedman ◽  
P. Birch
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
Optic Glioma ◽  
The Central Nervous System

Neurofibromatosis type 1 and high-grade tumors of the central nervous system

2009 ◽  
Vol 26 (5) ◽  
pp. 663-667 ◽  
Author(s):  
Amy Rosenfeld ◽  
Robert Listernick ◽  
Joel Charrow ◽  
Stewart Goldman
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
High Grade ◽  
The Central Nervous System

Neurofibromatosis Type 1 and Type 2: review of the central nervous system and related structures

1997 ◽  
Vol 19 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Yuichi Inoue ◽  
Yutaka Nemoto ◽  
Takahiko Tashiro ◽  
Keiko Nakayama ◽  
Tetsuo Nakayama ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Neurofibromatosis Type 1 ◽  
Neurofibromatosis Type ◽  
The Central Nervous System

scholarly journals Non-Oncological Neuroradiological Manifestations in NF1 and Their Clinical Implications

Cancers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1831
Author(s):  
Camilla Russo ◽  
Carmela Russo ◽  
Daniele Cascone ◽  
Federica Mazio ◽  
Claudia Santoro ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Structural Organization ◽  
Neurofibromatosis Type ◽  
Review Article ◽  
Tumor Suppressor Protein ◽  
Clinical Implications ◽  
Nf1 Gene ◽  
The Central Nervous System

Neurofibromatosis type 1 (NF1), the most frequent phakomatosis and one of the most common inherited tumor predisposition syndromes, is characterized by several manifestations that pervasively involve central and peripheral nervous system structures. The disorder is due to mutations in the NF1 gene, which encodes for the ubiquitous tumor suppressor protein neurofibromin; neurofibromin is highly expressed in neural crest derived tissues, where it plays a crucial role in regulating cell proliferation, differentiation, and structural organization. This review article aims to provide an overview on NF1 non-neoplastic manifestations of neuroradiological interest, involving both the central nervous system and spine. We also briefly review the most recent MRI functional findings in NF1.

scholarly journals An Update on Neurofibromatosis Type 1-Associated Gliomas

Cancers ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 114 ◽  
Author(s):  
Lobbous ◽  
Bernstock ◽  
Coffee ◽  
Friedman ◽  
Metrock ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Neurofibromatosis Type 1 ◽  
Autosomal Dominant ◽  
Neurofibromatosis Type ◽  
Central Nervous System Neoplasms ◽  
Therapeutic Landscape ◽  
Nervous System Neoplasms ◽  
Collaborative Efforts

Neurofibromatosis type 1 (NF1) is an autosomal dominant tumor predisposition syndrome that affects children and adults. Individuals with NF1 are at high risk for central nervous system neoplasms including gliomas. The purpose of this review is to discuss the spectrum of intracranial gliomas arising in individuals with NF1 with a focus on recent preclinical and clinical data. In this review, possible mechanisms of gliomagenesis are discussed, including the contribution of different signaling pathways and tumor microenvironment. Furthermore, we discuss the recent notable advances in the developing therapeutic landscape for NF1-associated gliomas including clinical trials and collaborative efforts.

Imaging considerations of central nervous system manifestations in pediatric patients with neurofibromatosis type 1

1991 ◽  
Vol 21 (6) ◽  
pp. 389-394 ◽  
Author(s):  
F. Menor ◽  
L. Martí-Bonmatí ◽  
F. Mulas ◽  
H. Cortina ◽  
R. Olagüe
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Neurofibromatosis Type 1 ◽  
Pediatric Patients ◽  
Neurofibromatosis Type

Central Nervous System Vascular Complications in Children and Adults with Neurofibromatosis Type 1 (P06.014)

Neurology ◽  
2012 ◽  
Vol 78 (Meeting Abstracts 1) ◽  
pp. P06.014-P06.014
Author(s):  
A. Bergner ◽  
B. Kaas ◽  
A. Chance ◽  
L. Jordan ◽  
J. Blakeley
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Neurofibromatosis Type 1 ◽  
Vascular Complications ◽  
Neurofibromatosis Type
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