Long-Term Benefit of Primary Angioplasty as Compared with Thrombolytic Therapy for Acute Myocardial Infarction

1999 ◽  
Vol 341 (19) ◽  
pp. 1413-1419 ◽  
Author(s):  
Felix Zijlstra ◽  
Jan C.A. Hoorntje ◽  
Menko-Jan de Boer ◽  
Stoffer Reiffers ◽  
Kor Miedema ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Thrombolytic Therapy ◽  
Primary Angioplasty ◽  
Term Benefit

Long-Term Benefit of Primary Angioplasty as Compared with Thrombolytic Therapy for Acute Myocardial Infarction

2000 ◽  
Vol 44 (5) ◽  
pp. 263
Author(s):  
FELIX ZIJLSTRA ◽  
JAN C.A. HOORNTJE ◽  
MENKO-JAN DE BOER ◽  
STOFFER REIFERS ◽  
KOR MIEDEMA ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Thrombolytic Therapy ◽  
Primary Angioplasty ◽  
Term Benefit

scholarly journals Short- and long-term mortality for patients undergoing primary angioplasty for acute myocardial infarction

2000 ◽  
Vol 36 (4) ◽  
pp. 1194-1201 ◽  
Author(s):  
Edward L Hannan ◽  
Michael J Racz ◽  
Djavad T Arani ◽  
Thomas J Ryan ◽  
Gary Walford ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Primary Angioplasty ◽  
Short And Long Term ◽  
Long Term Mortality

Long-term prognostic implications of nonoptimal primary angioplasty for acute myocardial infarction

2006 ◽  
Vol 68 (1) ◽  
pp. 50-55 ◽  
Author(s):  
Guido Parodi ◽  
Renato Valenti ◽  
Nazario Carrabba ◽  
Gentian Memisha ◽  
Guia Moschi ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Primary Angioplasty ◽  
Prognostic Implications

scholarly journals Primary Angioplasty for Acute Myocardial Infarction

1997 ◽  
Vol 2 (4) ◽  
pp. 327-334 ◽  
Author(s):  
Craig P Juergens ◽  
Robert J Whitbourn ◽  
Alan C Yeung ◽  
Stephen N Oesterle
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Thrombolytic Therapy ◽  
Significant Risk ◽  
Hospital Setting ◽  
Reperfusion Therapy ◽  
Primary Angioplasty ◽  
Coronary Perfusion ◽  
Short Term Mortality ◽  
Reperfusion Strategy

The use of thrombolytic therapy has been widely accepted for the treatment of acute myocardial infarction. Despite improving mortality, thrombolytic therapy may be contraindicated in many patients presenting with myocardial infarction and is associated with a small, yet significant risk of hemorrhagic sequelae. This article outlines the rationale behind reperfusion therapy, the use of pharmacological thrombolysis and the role of adjunctive angioplasty. The potential advantages of a therapeutic strategy of primary angioplasty, instead of thrombolysis, are discussed. These include anatomical definition, risk stratification, reduced recurrent ischemia, enhanced coronary perfusion and improved coronary patency. The randomized trials in which primary angioplasty and thrombolytic therapy were compared are reviewed. We conclude that angioplasty results in a reduction of short-term mortality and nonfatal reinfarction and therefore advocate the routine use of coronary angioplasty as a primary reperfusion strategy for acute myocardial infarction. The potential limitations of primary angioplasty in the community hospital setting are discussed. Finally, we examine the roles of adjunctive mechanical (e.g. stents) and pharmacological (e.g. Abciximab) means of further enhancing outcomes after primary angioplasty.

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