The thermal conductivity of heating or cooling fluids is a very important property in the development of energy efficient heat transfer systems, which is one of the important needs of many industries. However, low thermal conductivity is a primary limitation in developing energy-efficient heat transfer fluids that are required for cooling purposes. Nanofluids are nanotechnology-based heat transfer fluids that are engineered by stably dispersing nanometer-sized (below 100nm) solid particles (such as ceramics, metals, alloys, semiconductors, nanotubes, and composite particles) in conventional heat transfer fluids (such as water, oil, diesel, ethylene glycol and mixtures) at relatively low particle volume concentrations. These suspended nanoparticles can change the transport and thermal properties of the base fluid. Adding to ethylene glycol, it has been observed that an enhancement of nearly 36 % with al2o3 nanoparticles and 40% enhancement with copper nanoparticles in the thermal conductivity. This paper focuses on some of the automotive applications such as coolant for automobiles, showcases a few of them that are believed to have the highest probability of success in this highly competitive industry and to raise the awareness on the promise of nanotechnology, its potential impact on the future of the automotive industry.