A randomized, controlled trial of a simple emergency department intervention to improve the rate of primary care follow-up for patients with acute asthma exacerbations

2001 ◽  
Vol 38 (2) ◽  
pp. 115-122 ◽  
Author(s):  
Jill M. Baren ◽  
Frances S. Shofer ◽  
Bert Ivey ◽  
Sharon Reinhard ◽  
Jennifer DeGeus ◽  
...  
Keyword(s):  
Primary Care ◽  
Emergency Department ◽  
Randomized Controlled Trial ◽  
Acute Asthma ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Asthma Exacerbations ◽  
Acute Asthma Exacerbations

Randomized Controlled Trial of Emergency Department Interventions To Improve Primary Care Follow-up for Patients With Acute Asthma

CHEST Journal ◽  
2006 ◽  
Vol 129 (2) ◽  
pp. 257-265 ◽  
Author(s):  
Jill M. Baren ◽  
Edwin D. Boudreaux ◽  
Barry E. Brenner ◽  
Rita K. Cydulka ◽  
Brian H. Rowe ◽  
...  
Keyword(s):  
Primary Care ◽  
Emergency Department ◽  
Randomized Controlled Trial ◽  
Acute Asthma ◽  
Controlled Trial ◽  
Randomized Controlled

Randomized controlled trial to improve primary care follow-up among emergency department patients

2020 ◽  
Vol 38 (6) ◽  
pp. 1115-1122
Author(s):  
Rory J. Merritt ◽  
Paige Kulie ◽  
Andrew W. Long ◽  
Tina Choudhri ◽  
Melissa L. McCarthy
Keyword(s):  
Primary Care ◽  
Emergency Department ◽  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Emergency Department Patients

scholarly journals Oral dexamethasone for the prevention of acute migraine recurrence in pediatric patients presenting to the emergency department with migraine

2018 ◽  
Vol 1 ◽  
pp. 251581631880415
Author(s):  
Serena L Orr ◽  
Lawrence Richer ◽  
Nick Barrowman ◽  
Roger Zemek
Keyword(s):  
Emergency Department ◽  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Pilot Trial ◽  
Recruitment Rate ◽  
Efficacy And Safety ◽  
Randomized Controlled ◽  
Oral Dexamethasone ◽  
Safety Outcomes

Objective: To assess the feasibility of a randomized controlled trial protocol that aims to determine the efficacy and safety of oral dexamethasone compared to placebo for the prevention of migraine recurrence in children and adolescents visiting the pediatric emergency department (ED) with migraine. Methods: This study was a two-arm, parallel-group, randomized, placebo-controlled, double-blind pilot trial of patients presenting to the pediatric ED with migraine. Eligible participants were randomized at 1:1 ratio to receive either oral dexamethasone 0.6 mg/kg (maximum 15 mg) or matched placebo as a single dose. Efficacy and safety outcomes were assessed at discharge, 48 h and 7 days after discharge. The primary outcome of the trial was feasibility and was assessed through participant recruitment rate, follow-up completion rates, participant satisfaction ratings and comparison of enrolled versus non-enrolled participants. Efficacy and safety outcomes were not analyzed given that this was a pilot study. Results: Twelve participants were enrolled over the 6-month recruitment period. This represents 60% of the planned sample size and a 10.5% recruitment rate. No other feasibility issues were identified and patients expressed high satisfaction rates with their treatment: 90.9% were satisfied with their treatment at discharge and at 48-h follow-up and 81.8% were satisfied with their treatment at 7-day follow-up (81.8%). There were no significant differences observed when comparing enrolled participants to those not enrolled. Conclusion: This pilot randomized controlled trial is the first to assess dexamethasone in the pediatric ED for the prevention of migraine recurrence. The protocol is feasible but recruitment in a single center was lower than expected. Future pediatric ED migraine studies may use innovative or pragmatic trial designs to maximize feasibility from a recruitment standpoint.

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