Inhibition of Phosphatidylinositol 3-Kinase Activity Blocks Depolarization- and Insulin-like Growth Factor I-mediated Survival of Cerebellar Granule Cells

Journal of Biological Chemistry ◽

10.1074/jbc.272.15.9847 ◽

1997 ◽

Vol 272 (15) ◽

pp. 9847-9853 ◽

Author(s):

Timothy M. Miller ◽

Malú G. Tansey ◽

Eugene M. Johnson ◽

Douglas J. Creedon

Keyword(s):

Growth Factor ◽

Kinase Activity ◽

Granule Cells ◽

Cerebellar Granule Cells ◽

Insulin Like Growth Factor ◽

Phosphatidylinositol 3 Kinase ◽

Cerebellar Granule ◽

Factor I ◽

Growth Factor I ◽

Phosphatidylinositol 3

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Insulin-like growth factor I (IGF-I) is a critical trophic factor for developing cerebellar granule cells

Developmental Brain Research ◽

10.1016/s0165-3806(97)00015-1 ◽

1997 ◽

Vol 99 (2) ◽

pp. 234-242 ◽

Author(s):

Xi Lin ◽

Robert F Bulleit

Keyword(s):

Growth Factor ◽

Granule Cells ◽

Cerebellar Granule Cells ◽

Trophic Factor ◽

Insulin Like Growth Factor ◽

Cerebellar Granule ◽

Factor I ◽

Igf I ◽

Growth Factor I

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Insulin-Like Growth Factor I Prevents the Development of Sensitivity to Kainate Neurotoxicity in Cerebellar Granule Cells

Journal of Neurochemistry ◽

10.1046/j.1471-4159.2000.0751548.x ◽

2002 ◽

Vol 75 (4) ◽

pp. 1548-1556 ◽

Author(s):

Michael L. Leski ◽

Stacey L. Valentine ◽

Jesse D. Baer ◽

Joseph T. Coyle

Keyword(s):

Growth Factor ◽

Granule Cells ◽

Cerebellar Granule Cells ◽

Insulin Like Growth Factor ◽

Cerebellar Granule ◽

Factor I ◽

Growth Factor I

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Specific Increase in p85α Expression in Response to Dexamethasone Is Associated with Inhibition of Insulin-like Growth Factor-I Stimulated Phosphatidylinositol 3-Kinase Activity in Cultured Muscle Cells

Journal of Biological Chemistry ◽

10.1074/jbc.272.11.7455 ◽

1997 ◽

Vol 272 (11) ◽

pp. 7455-7463 ◽

Author(s):

Francesco Giorgino ◽

Michael T. Pedrini ◽

Lucrezia Matera ◽

Robert J. Smith

Keyword(s):

Growth Factor ◽

Kinase Activity ◽

Muscle Cells ◽

Insulin Like Growth Factor ◽

Phosphatidylinositol 3 Kinase ◽

Factor I ◽

Specific Increase ◽

Growth Factor I ◽

Phosphatidylinositol 3

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Recombinant human insulin-like growth factor I exerts a trophic action and confers glutamate sensitivity on glutamate-resistant cerebellar granule cells.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.90.18.8752 ◽

1993 ◽

Vol 90 (18) ◽

pp. 8752-8756 ◽

Author(s):

P. Calissano ◽

M. T. Ciotti ◽

L. Battistini ◽

C. Zona ◽

A. Angelini ◽

...

Keyword(s):

Growth Factor ◽

Human Insulin ◽

Granule Cells ◽

Cerebellar Granule Cells ◽

Insulin Like Growth Factor ◽

Recombinant Human Insulin ◽

Cerebellar Granule ◽

Factor I ◽

Growth Factor I ◽

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Insulin like growth factor-I induces limited association of phosphatidylinositol 3-kinase to its receptor.

Endocrinology ◽

10.1210/endo.130.3.1311242 ◽

1992 ◽

Vol 130 (3) ◽

pp. 1490-1498 ◽

Author(s):

K Yamamoto ◽

E G Lapetina ◽

C P Moxham

Keyword(s):

Growth Factor ◽

Insulin Like Growth Factor ◽

Phosphatidylinositol 3 Kinase ◽

Factor I ◽

Growth Factor I ◽

Phosphatidylinositol 3

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The Phosphatidylinositol-3 kinase Pathway Is Not Essential for Insulin-like Growth Factor I Receptor-mediated Clonogenic Radioresistance

Journal of Radiation Research ◽

10.1269/jrr.43.325 ◽

2002 ◽

Vol 43 (3) ◽

pp. 325-329 ◽

Author(s):

DONG YU ◽

HIROSHI WATANABE ◽

HITOSHI SHIBUYA ◽

MASAHIKO MIURA

Keyword(s):

Growth Factor ◽

Insulin Like Growth Factor ◽

Phosphatidylinositol 3 Kinase ◽

Factor I ◽

Growth Factor I ◽

Kinase Pathway ◽

Phosphatidylinositol 3

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Insulin-like Growth Factor-I Inhibits Transcriptional Responses of Transforming Growth Factor-β by Phosphatidylinositol 3-Kinase/Akt-dependent Suppression of the Activation of Smad3 but Not Smad2

Journal of Biological Chemistry ◽

10.1074/jbc.m304583200 ◽

2003 ◽

Vol 278 (40) ◽

pp. 38342-38351 ◽

Author(s):

Kyung Song ◽

Susan C. Cornelius ◽

Michael Reiss ◽

David Danielpour

Keyword(s):

Growth Factor ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β ◽

Insulin Like Growth Factor ◽

Phosphatidylinositol 3 Kinase ◽

Transcriptional Responses ◽

Factor I ◽

Growth Factor I ◽

Phosphatidylinositol 3

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Insulin-Like Growth Factor-I Inhibits Dexamethasone-Induced Catabolism in Cultured L6 Myotubes by Activation of Phosphatidylinositol 3-Kinase

Journal of Burn Care & Rehabilitation ◽

10.1097/00004630-200303002-00195 ◽

2003 ◽

Vol 24 ◽

pp. S140

Author(s):

&NA;

Keyword(s):

Growth Factor ◽

Insulin Like Growth Factor ◽

Phosphatidylinositol 3 Kinase ◽

Factor I ◽

L6 Myotubes ◽

Growth Factor I ◽

Phosphatidylinositol 3

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Insulin like growth factor-I induces limited association of phosphatidylinositol 3-kinase to its receptor

Endocrinology ◽

10.1210/en.130.3.1490 ◽

1992 ◽

Vol 130 (3) ◽

pp. 1490-1498 ◽

Author(s):

K. Yamamoto

Keyword(s):

Growth Factor ◽

Insulin Like Growth Factor ◽

Phosphatidylinositol 3 Kinase ◽

Factor I ◽

Growth Factor I ◽

Phosphatidylinositol 3

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Mitogen-Activated Protein Kinase and Phosphatidylinositol 3-Kinase Pathways Are Not Sufficient for Insulin-Like Growth Factor I-Induced Mitogenesis and Tumorigenesis

Endocrinology ◽

10.1210/endo.138.6.5215 ◽

1997 ◽

Vol 138 (6) ◽

pp. 2552-2558 ◽

Author(s):

Angus G. Scrimgeour ◽

Vicky A. Blakesley ◽

Bethel S. Stannard ◽

Derek LeRoith

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Mitogen Activated Protein Kinase ◽

Insulin Like Growth Factor ◽

Phosphatidylinositol 3 Kinase ◽

Factor I ◽

Mitogen Activated Protein ◽

Growth Factor I ◽

Phosphatidylinositol 3

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