scholarly journals Effects of green tea on weight maintenance after body-weight loss

2004 ◽  
Vol 91 (3) ◽  
pp. 431-437 ◽  
Author(s):  
Eva M. R. Kovacs ◽  
Manuela P. G. M. Lejeune ◽  
Ilse Nijs ◽  
Margriet S. Westerterp-Plantenga

The present study was conducted to investigate whether green tea may improve weight maintenance by preventing or limiting weight regain after weight loss of 5 to 10% in overweight and moderately obese subjects. The study had a randomised, parallel, placebo-controlled design. A total of 104 overweight and moderately obese male and female subjects (age 18–60 years; BMI 25–35kg/m2) participated. The study consisted of a very-low-energy diet intervention (VLED; 2·1MJ/d) of 4 weeks followed by a weight-maintenance period of 13 weeks in which the subjects received green tea or placebo. The green tea contained caffeine (104mg/d) and catechins (573mg/d, of which 323mg was epigallocatechin gallate). Subjects lost 6·4 (sd 1·9) kg or 7·5 (sd 2·2) % of their original body weight during the VLED (P<0·001). Body-weight regain was not significantly different between the green tea and the placebo group (30·5 (sd 61·8) % and 19·7 (sd 56·9)%, respectively). In the green tea treatment, habitual high caffeine consumption was associated with a higher weight regain compared with habitual low caffeine consumption (39 (sd 17) and 16 (sd 11)%, respectively; P<0·05). We conclude that weight maintenance after 7·5% body-weight loss was not affected by green tea treatment and that habitual caffeine consumption affected weight maintenance in the green tea treatment.

2005 ◽  
Vol 13 (7) ◽  
pp. 1195-1204 ◽  
Author(s):  
Margriet S. Westerterp-Plantenga ◽  
Manuela P.G.M. Lejeune ◽  
Eva M. R. Kovacs

2006 ◽  
Vol 95 (1) ◽  
pp. 160-167 ◽  
Author(s):  
Tanja C. M Adam ◽  
Manuela P. G. M. Lejeune ◽  
Margriet S. Westerterp-Plantenga

Glucagon-like peptide 1 (GLP-1) is a peptide hormone that is released in response to nutrient ingestion. Postprandial GLP-1 release has been reported to be attenuated in obese subjects, but reports on the effect of weight loss on GLP-1 are conflicting. The aim of the present study was to clarify the effect of a weight-loss period and a consecutive weight-maintenance period on nutrient-stimulated GLP-1 release in obese subjects. Nutrient-stimulated (standard breakfast; 1·9MJ) GLP-1 release was investigated in thirty-two obese subjects on three occasions: before weight loss (T1) (BMI 30·0 (sd 2·5) kg/m2); after a 6-week very-low-energy diet (VLED) (T2) (BMI 27·6 (sd 2·3) kg/m2); after a 3-month weight-maintenance period (T3) (BMI 27·9 (sd 2·3) kg/m2). At each occasion, following a fasting blood sample the test meal was fed and blood was drawn every 30min for 2h relative to ingestion in order to determine plasma GLP-1, insulin, glucose and NEFA concentrations. Subjects lost 7 (sd 3·4) kg during the VLED (P<0·0001) and regained 1 (sd 3·2) kg during the weight-maintenance period (NS). The area under the curve for nutrient-stimulated plasma GLP-1 (pmol/l×h) was significantly decreased (P=0·01) at T2 (6·8 (sd 1)) compared with T1 (12·8 (sd 2·9)) and T3 (11·1 (sd 1·5)). Since we found a rebound of concentrations after a weight-maintenance period, decrease after weight loss seems to be transient and possibly due to a negative energy balance.


Children ◽  
2018 ◽  
Vol 5 (9) ◽  
pp. 116 ◽  
Author(s):  
Alexander Toth ◽  
Gricelda Gomez ◽  
Alpana Shukla ◽  
Janey Pratt ◽  
Hellas Cena ◽  
...  

This paper presents a retrospective cohort study of weight loss medications in young adults aged 21 to 30 following Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) between November 2000 and June 2014. Data were collected from patients who used topiramate, phentermine, and/or metformin postoperatively. Percentage of patients achieving ≥5%, ≥10%, or ≥15% weight loss on medications was determined and percent weight change on each medication was compared to percent weight change of the rest of the cohort. Our results showed that 54.1% of study patients lost ≥5% of their postsurgical weight; 34.3% and 22.9% lost ≥10% and ≥15%, respectively. RYGB had higher median percent weight loss (−8.1%) than SG (−3.3%) (p = 0.0515). No difference was found in median percent weight loss with medications started at weight plateau (−6.0%) versus after weight regain (−5.4%) (p = 0.5304). Patients taking medications at weight loss plateau lost 41.2% of total body weight from before surgery versus 27.1% after weight regain (p = 0.076). Median percent weight change on metformin was −2.9% compared to the rest of the cohort at −7.7% (p = 0.0241). No difference from the rest of the cohort was found for phentermine (p = 0.2018) or topiramate (p = 0.3187). Topiramate, phentermine, and metformin are promising weight loss medications for 21 to 30 year olds. RYGB patients achieve more weight loss on medications but both RYGB and SG benefit. Median total body weight loss from pre-surgical weight may be higher in patients that start medication at postsurgical nadir weight. Participants on metformin lost significantly smaller percentages of weight on medications, which could be the result of underlying medical conditions.


2004 ◽  
Vol 28 (7) ◽  
pp. 906-911 ◽  
Author(s):  
E Bobbioni-Harsch ◽  
O Bongard ◽  
F Habicht ◽  
D Weimer ◽  
H Bounameaux ◽  
...  

2011 ◽  
Vol 72 (4) ◽  
pp. 181-185 ◽  
Author(s):  
Lone Brinkmann Sørensen ◽  
Tine Greve ◽  
Martin Kreutzer ◽  
Ulla Pedersen ◽  
Claus Meyer Nielsen ◽  
...  

We compared the effect on weight regain of behaviour modification consisting of either a gourmet cooking course or neurolinguistic programming (NLP) therapy. Fifty-six overweight and obese subjects participated. The first step was a 12-week weight loss program. Participants achieving at least 8% weight loss were randomized to five months of either NLP therapy or a course in gourmet cooking. Follow-up occurred after two and three years. Forty-nine participants lost at least 8% of their initial body weight and were randomized to the next step. The NLP group lost an additional 1.8 kg and the cooking group lost 0.2 kg during the five months of weight maintenance (NS). The dropout rate in the cooking group was 4%, compared with 26% in the NLP group (p=0.04). There was no difference in weight maintenance after two and three years of follow-up. In conclusion, weight loss in overweight and obese participants was maintained equally efficiently with a healthy cooking course or NLP therapy, but the dropout rate was lower during the active cooking treatment.


Author(s):  
Cassandra Towns ◽  
Roschelle Heuberger ◽  
Jack Logomarsino ◽  
Arturo Olivera Jr.

Purpose: Evaluate weight maintenance in subjects who lost weight while taking phentermine (PTM). Methods: This study was conducted by utilizing a validated survey to collect self-reported data about weight changes post-PTM use. The survey was sent to 19,986 email addresses of current and former patients of a PTM-based outpatient clinic, located in Chicago, IL; 546 participants completed the survey. Results were analyzed using a variety of techniques. Results: At the time of the survey, 42% of responders maintained all the weight lost while on PTM, and 25.2% had maintained a weight loss of at least 10% of their body weight. The average weight lost and maintained at the time of the survey was 3.75% ± 13.8% of body weight or 8.74 lbs ± 27.45 lbs. Nineteen responders had no net weight change. Fifty-nine responders reported a net weight gain, ranging from 2 to 70 lbs with a mean net weight gain of 16.07 lbs ± 13.87 lbs. The duration of time since discontinuing PTM use had a significant correlation with weight maintenance: r = 0.340, p value = .000. There was no significant correlation between duration of time using PTM and weight maintenance. No correlations were identified between education, income, or ethnicity and weight maintenance. A correlation was identified between weight maintenance and current exercise level: r = 0.218, p value = .000. Conclusions: Although more research is needed, with the results of this study, the investigators suggest that post-PTM use, weight regain is not significantly higher than weight regain through other weight loss programs. In order to achieve long-term weight loss maintenance, it may behoove patients to receive professional guidance about behavior modifications to maintain weight lost, particularly related to exercise and dietary changes. The investigators of this study suggest greater emphasis on behavior modification in patients taking PTM is indicated.


2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
M. Glud ◽  
T. Christiansen ◽  
L. H. Larsen ◽  
B. Richelsen ◽  
J. M. Bruun

Circulating BDNF is higher in women than in men and suggested to be affected by changes in food intake, body weight, and exercise. The purpose of this study was to compare BDNF concentrations in women and men during a 12-week weight loss intervention. Using a previously published 12-week randomized study, serum BDNF was assessed at baseline and after 12 weeks using an enzyme-linked immunosorbent assay method. Fifty overweight or obese but healthy individuals (26 women, mean age of 36.4 ± 7.9 years; 24 men, mean age of 38.0 ± 5.9 years) were included and allocated into three groups: exercise-only (EXO; 12 weeks of aerobic exercise and isocaloric diet), diet-only (DIO; 8 weeks of very low energy diet (VLED 600 kcal/day) followed by a 4-week weight maintenance diet), or diet and exercise (DEX; 12 weeks of aerobic exercise in parallel with 8 weeks of VLED (800 kcal/day) followed by a 4-week weight maintenance diet). At baseline, BDNF levels were 25% higher in women compared to men (p=0.006). Body weight was reduced in all intervention groups (p<0.006). Exercise (EXO group) induced a 22% reduction in circulating BDNF in men (p=0.037) and women (p=0.080). In the DIO and DEX groups, a significant reduction in BDNF levels (29.9%; p=0.035 and 32.5%; p=0.003, respectively) was observed in women but not in men. In conclusion, circulating BDNF was significantly changed by diet alone or combined with exercise in women and only by exercise alone in men. This suggests that changes in circulating BDNF depend on weight loss methods (diet/exercise) as well as sex.


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