scholarly journals A Newn-Alkane Oxidation System fromPseudomonas aeruginosaS7B1

1981 ◽  
Vol 45 (1) ◽  
pp. 9-14
Author(s):  
Hidetoshi Matsuyama ◽  
Tadaatsu Nakahara ◽  
Yasuji Minoda
Keyword(s):  
Alkane Oxidation ◽  
Oxidation System

scholarly journals A new n-alkane oxidation system from Pseudomonas aeruginosa S7B1.

1981 ◽  
Vol 45 (1) ◽  
pp. 9-14 ◽  
Author(s):  
Hidetoshi MATSUYAMA ◽  
Tadaatsu NAKAHARA ◽  
Yasuji MINODA
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Alkane Oxidation ◽  
Oxidation System

scholarly journals PPARα Signaling is Activated by Cocoa in Mouse Liver

2013 ◽  
Vol 8 (5) ◽  
pp. 1934578X1300800
Author(s):  
Marco Fidaleo ◽  
Claudia Sartori
Keyword(s):  
Mouse Liver ◽  
Target Genes ◽  
Signal Modulation ◽  
Sod1 Gene ◽  
Serum Triglycerides ◽  
Oxidative Balance ◽  
Gene Level ◽  
Direct Binding ◽  
Somatic Index ◽  
Oxidation System

In this study we evaluated in mouse liver the effects of cocoa on PPARα signaling. To this aim, mouse diet was supplemented with 10%, w/w, cocoa for one and two weeks. We quantified the expression of PPARα target genes and PPARα gene level and some parameters related to PPARα activation (hepato-somatic index, peroxisomal β-oxidation system and catalase activity). Moreover, we evaluated antioxidant capacity of cocoa by detecting the expression of CAT and SOD1 genes (known to be involved in oxidative balance) and hypolipidemic properties on serum triglycerides. We made a parallel treatment with 0.025%, w/w, ciprofibrate, a well-known PPARα activator, to quantify signal modulation by cocoa. It is known that PPARα activation by ciprofibrate is mediated by direct binding to the receptor and strongly induces expression of target genes. Our results show that cocoa weakly up-regulates PPARα target genes as a consequence of the modulation of the PPARα gene level and does not improve the triglyceride profile in blood. Finally, cocoa increased SOD1 gene expression suggesting an antioxidant effect.

scholarly journals An in vitro demonstration of peroxisome proliferation and increase in peroxisomal β-oxidation system mRNAs in cultured rat hepatocytes treated with ciprofibrate

FEBS Letters ◽  
1989 ◽  
Vol 250 (2) ◽  
pp. 205-210 ◽  
Author(s):  
Shobha Thangada ◽  
Keith Alvares ◽  
Mario Mangino ◽  
Mohammed I. Usman ◽  
M.Sambasiva Rao ◽  
...  
Keyword(s):  
Rat Hepatocytes ◽  
Peroxisome Proliferation ◽  
Cultured Rat Hepatocytes ◽  
Oxidation System
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