(+)-Trichostatin A, a Potent Differentiation Inducer of Friend Leukemia Cells

1988 ◽  
Vol 52 (1) ◽  
pp. 251-253
Author(s):  
Hajimu Morioka ◽  
Masaru Ishihara ◽  
Misako Takezawa ◽  
Hiroshiro Shibai ◽  
Yasuo Komoda
1988 ◽  
Vol 52 (1) ◽  
pp. 251-253 ◽  
Author(s):  
Hajimu MORIOKA ◽  
Masaru ISHIHARA ◽  
Misako TAKEZAWA ◽  
Hiroshiro SHIBAI ◽  
Yasuo KOMODA

1985 ◽  
Vol 49 (5) ◽  
pp. 1365-1370 ◽  
Author(s):  
Hajimu Morioka ◽  
Masaru Ishihara ◽  
Misako Takezawa ◽  
Kazuo Hirayama ◽  
Eiichiro Suzuki ◽  
...  

1985 ◽  
Vol 49 (10) ◽  
pp. 2835-2842
Author(s):  
Hajimu Morioka ◽  
Misako Takezawa ◽  
Hiroshiro Shibai

1985 ◽  
Vol 49 (5) ◽  
pp. 1365-1370 ◽  
Author(s):  
Hajimu MORIOKA ◽  
Masaru ISHIHARA ◽  
Misako TAKEZAWA ◽  
Kazuo HIRAYAMA ◽  
Eiichiro SUZUKI ◽  
...  

1985 ◽  
Vol 49 (10) ◽  
pp. 2835-2842 ◽  
Author(s):  
Hajimu MORIOKA ◽  
Misako TAICEZAWA ◽  
Hiroshiro SHIBAI

Author(s):  
W. Djaczenko ◽  
M. Müller ◽  
A. Benedetto ◽  
G. Carbone

A thickening of ER membranes in murine myeloma cells was attributed by de Harven to the assembly of intracisternal virus particles. We observed similar thickening of GER membranes in Friend leukemia cells (FLC) apparently associated with Friend leukemia virus (FLV) assembly. We reinvestigated the problem of GER involvement in FLV assembly using high pressure cryofixed FLC.FLC (745A clone growing in suspension and FF clone growing in monolayer) were immersed in Hexadecene (Fluka, Switzerland) and rapidly frozen in Balzers HPM 010 freezing machine working at 2200 bar. All cells were freeze substituted at -90°C in 2% OsO4 in absolute acetone. Serial sections cut to avoid misinterpretations due to the geometry of sections, were collected on carbon coated 100 mesh grids.


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