Diagnostic value of the hypertonic saline bronchial provocation test in children with asthma using the high-power aerosol provocation system

2020 ◽  
pp. 1-8
Author(s):  
Ming-juan Zhou ◽  
Yuan-bin Chen ◽  
Wen-wei Ouyang ◽  
Chu-yin Ye ◽  
Jun-liang Ye ◽  
...  
Keyword(s):  
Hypertonic Saline ◽  
High Power ◽  
Provocation Test ◽  
Diagnostic Value ◽  
Bronchial Provocation Test ◽  
Children With Asthma ◽  
Bronchial Provocation

Different cutoff values of methacholine bronchial provocation test depending on age in children with asthma

2017 ◽  
Vol 13 (5) ◽  
pp. 439-445 ◽  
Author(s):  
Eun Lee ◽  
Young-Ho Kim ◽  
Seungbong Han ◽  
Song-I Yang ◽  
Young-Ho Jung ◽  
...  
Keyword(s):  
Provocation Test ◽  
Cutoff Values ◽  
Bronchial Provocation Test ◽  
Children With Asthma ◽  
Bronchial Provocation

scholarly journals Bronchial provocation test measured by using the forced oscillation technique to assess airway responsiveness

2021 ◽  
Vol 42 (5) ◽  
pp. e127-e134
Author(s):  
Hui Xu ◽  
Yi Gao ◽  
Yanqing Xie ◽  
Xiaolin Liang ◽  
Jinping Zheng
Keyword(s):  
Cumulative Dose ◽  
Healthy Subjects ◽  
Forced Oscillation ◽  
Provocation Test ◽  
Diagnostic Value ◽  
Airway Responsiveness ◽  
Forced Oscillation Technique ◽  
Time Saving ◽  
Bronchial Provocation Test ◽  
Bronchial Provocation

Background: The bronchial provocation test (BPT) performed by using the forced oscillation technique (FOT) is cooperated without forced expiratory effort. However, a comparison of the application value and safety of BPTs measured by using the FOT and the standardized dosimeter method is lacking, which limits its clinical practice. Objective: We aimed to analyze the diagnostic value and safety of the BPT as measured by the FOT in patients with asthma and in healthy subjects. Methods: This was a randomized cross-over clinical study. Airway responsiveness was measured by using the FOT and the aerosol provocation system (APS) dosimeter method in all the participants. The between-test interval was 24 hours. The diagnostic value and safety of the two tests were analyzed. Results: Asthma control status was assessed based on ACT scores, and patients with asthma (including 27 uncontrolled, 34 partially controlled, and 32 controlled) were collected, and 69 healthy subjects were recruited. Receiver operating characteristic curves revealed slightly superior screening capability of cumulative dose of methacholine causing a 20% decrease (PD20)‐forced expiratory volume in the first second of expiration when measured by using the APS-dosimeter method (area under the curve [AUC] 0.981 [95% confidence interval {CI}, 0.952‐1.000]) over that of cumulative dose of inhaled methacholine at the inflection point when respiratory resistance began to increase continuously (Dmin) by using the FOT (AUC 0.959 [95% CI, 0.924‐0.994]). The sensitivity and specificity were 98.9% and 98.6%, respectively, with the APS-dosimeter method, and 100% and 87.0%, respectively, with the FOT. It took an average of 9.0 minutes (range, 6.0‐11.0 minutes) when using the FOT and an average of 17.0 minutes (range, 14.0‐25.0 minutes) when using APS-dosimeter method (p < 0.01) in all the participants. The measurement time for the FOT was reduced by 47.1% than the APS-dosimeter. The incidence rate of the adverse events with the FOT was slightly higher than that with the APS-dosimeter method (p < 0.05). Both tests were well tolerated. No serious adverse event was found. Conclusion: The FOT, characterized as being simple, safe, and time saving, could be used to assess airway hyperresponsiveness in patients with asthma and worthy of clinical application.

Diagnostic Value of the Bronchial Provocation Test With Methacholine in Asthma

CHEST Journal ◽  
1993 ◽  
Vol 104 (1) ◽  
pp. 149-154 ◽  
Author(s):  
Miguel Perpiñá ◽  
Concha Pellicer ◽  
Alfredo de Diego ◽  
Luis Compte ◽  
Vicente Macián
Keyword(s):  
Provocation Test ◽  
Diagnostic Value ◽  
Bronchial Provocation Test ◽  
Bronchial Provocation

Leukotriene D4 bronchial provocation test: methodology and diagnostic value

2012 ◽  
Vol 28 (5) ◽  
pp. 797-803 ◽  
Author(s):  
Weijie Guan ◽  
Jinping Zheng ◽  
Yi Gao ◽  
Caiyu Jiang ◽  
Jiaying An ◽  
...  
Keyword(s):  
Provocation Test ◽  
Diagnostic Value ◽  
Leukotriene D4 ◽  
Test Methodology ◽  
Bronchial Provocation Test ◽  
Bronchial Provocation

Prevalence of childhood asthma based on questionnaires and methacholine bronchial provocation test in Korea

1997 ◽  
Vol 27 (7) ◽  
pp. 761-768 ◽  
Author(s):  
Y. Y. KIM ◽  
S. H. CHO ◽  
W. K. KIM ◽  
J. K. PARK ◽  
S. H. SONG ◽  
...  
Keyword(s):  
Childhood Asthma ◽  
Provocation Test ◽  
Bronchial Provocation Test ◽  
Bronchial Provocation

scholarly journals Does the asthma control test reflect inflammation?

2019 ◽  
Vol 6 ◽  
Author(s):  
Margherita Neri
Keyword(s):  
Asthma Control ◽  
Pulmonary Function Tests ◽  
Provocation Test ◽  
Control Test ◽  
Asthma Control Test ◽  
Asthmatic Patients ◽  
Bronchial Provocation Test ◽  
Nitric Oxide Level ◽  
The Relationship ◽  
Bronchial Provocation

The present issue of Multidisciplinary Respiratory Medicine includes a paper by Bora et al. [1] investigating the relationship between the asthma control test (ACT) and airway inflammation. In a group of stable asthmatic patients admitted to a pulmonary outpatient clinic, the authors carried out the ACT, pulmonary function tests, methacholine bronchial provocation test (MBPT), fractional exhaled nitric oxide level (FeNO), and induced sputum test. [...]

scholarly journals THE BRONCHIAL PROVOCATION TEST

CHEST Journal ◽  
1975 ◽  
Vol 68 (4) ◽  
pp. 29 ◽  
Author(s):  
John M. O’Loughlin
Keyword(s):  
Provocation Test ◽  
Bronchial Provocation Test ◽  
Bronchial Provocation
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