scholarly journals A new approach for modeling patient overall radiosensitivity and predicting multiple toxicity endpoints for breast cancer patients

2018 ◽  
Vol 57 (5) ◽  
pp. 604-612 ◽  
Author(s):  
Chamberlain Mbah ◽  
Kim De Ruyck ◽  
Silke De Schrijver ◽  
Charlotte De Sutter ◽  
Kimberly Schiettecatte ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
New Approach

scholarly journals Immunooncology in Breast Cancer: Active and Passive Vaccination Strategies

Breast Care ◽  
2018 ◽  
Vol 13 (1) ◽  
pp. 22-26
Author(s):  
Florian Schütz ◽  
Frederik Marmé ◽  
Christoph Domschke ◽  
Christof Sohn ◽  
Alexandra von Au
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
New Technologies ◽  
Breast Cancer Patients ◽  
New Approach ◽  
Tumor Associated Antigen ◽  
Specific Tumor ◽  
Car T ◽  
Passive Vaccination ◽  
Near Future

Immunotherapies are set to become part of the therapeutic repertoire for breast cancer in the near future. Active vaccination is a promising strategy, especially in tumors that have a specific tumor-associated antigen. Although cellular immunotherapies have not yet shown efficacy, new technologies are on the way to improve this approach. Given the recent Food and Drug Administration approval of chimeric antigen receptor (CAR) T cells for leukemia, it is only a question of time before solid tumors will follow. However, not all breast cancer patients will respond to cellular or other immunotherapy. Hence, we must define subpopulations of breast cancer patients who benefit from this new approach.

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