CROSS-FOSTERING INHALATION TOXICITY STUDY WITH HCFC-123 IN LACTATING SPRAGUE-DAWLEY RATS

2001 ◽  
Vol 13 (8) ◽  
pp. 671-687 ◽  
Author(s):  
Jochen Buschmann ◽  
Wilfried Bartsch ◽  
Clemens Dasenbrock ◽  
Rainer Fuhst ◽  
Gerhard Pohlmann ◽  
...  
Keyword(s):  
Toxicity Study ◽  
Inhalation Toxicity ◽  
Sprague Dawley ◽  
Sprague Dawley Rats ◽  
Cross Fostering ◽  
Hcfc 123

90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats

2021 ◽  
pp. 112780
Author(s):  
Shu-Chieh Hu ◽  
Seonggi Min ◽  
Hyun-Ki Kang ◽  
Dong-Jin Yang ◽  
Mallikarjuna Basavarajappa ◽  
...  
Keyword(s):  
Toxicity Study ◽  
Inhalation Toxicity ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

scholarly journals Twenty-Eight-Day Repeated Inhalation Toxicity Study of Aluminum Oxide Nanoparticles in Male Sprague-Dawley Rats

2018 ◽  
Vol 34 (4) ◽  
pp. 343-354 ◽  
Author(s):  
Yong-Soon Kim ◽  
Yong-Hyun Chung ◽  
Dong-Seok Seo ◽  
Hyun-Sung Choi ◽  
Cheol-Hong Lim
Keyword(s):  
Aluminum Oxide ◽  
Toxicity Study ◽  
Oxide Nanoparticles ◽  
Inhalation Toxicity ◽  
Sprague Dawley ◽  
Aluminum Oxide Nanoparticles ◽  
Sprague Dawley Rats

Twenty-Eight-Day Inhalation Toxicity Study of Silver Nanoparticles in Sprague-Dawley Rats

2007 ◽  
Vol 19 (10) ◽  
pp. 857-871 ◽  
Author(s):  
Jun Ho Ji ◽  
Jae Hee Jung ◽  
Sang Soo Kim ◽  
Jin-Uk Yoon ◽  
Jung Duck Park ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Toxicity Study ◽  
Inhalation Toxicity ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

Twenty-eight-day repeated inhalation toxicity study of nano-sized lanthanum oxide in male sprague-dawley rats

2016 ◽  
Vol 32 (4) ◽  
pp. 1226-1240 ◽  
Author(s):  
Seo-Ho Shin ◽  
Cheol-Hong Lim ◽  
Yong-Soon Kim ◽  
Yong-Hoon Lee ◽  
Sung-Hwan Kim ◽  
...  
Keyword(s):  
Lanthanum Oxide ◽  
Toxicity Study ◽  
Inhalation Toxicity ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

scholarly journals Twenty-Eight-Day Repeated Inhalation Toxicity Study of Nano-Sized Neodymium Oxide in Male Sprague-Dawley Rats

2017 ◽  
Vol 33 (3) ◽  
pp. 239-253 ◽  
Author(s):  
Yong-Soon Kim ◽  
Cheol-Hong Lim ◽  
Seo-Ho Shin ◽  
Jong-Choon Kim
Keyword(s):  
Neodymium Oxide ◽  
Toxicity Study ◽  
Inhalation Toxicity ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

scholarly journals Acute and 28-Day Repeated Inhalation Toxicity Study of Glycolic Acid in Male Sprague-Dawley Rats

In Vivo ◽  
2019 ◽  
Vol 33 (5) ◽  
pp. 1507-1519 ◽  
Author(s):  
SEONG KWANG LIM ◽  
JEAN YOO ◽  
HAEWON KIM ◽  
WOONG KIM ◽  
ILSEOB SHIM ◽  
...  
Keyword(s):  
Glycolic Acid ◽  
Toxicity Study ◽  
Inhalation Toxicity ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

Subacute inhalation toxicity study of synthetic amorphous silica nanoparticles in Sprague-Dawley rats

2017 ◽  
Vol 29 (12-14) ◽  
pp. 567-576 ◽  
Author(s):  
Jae Hoon Shin ◽  
KiSoo Jeon ◽  
Jin Kwon Kim ◽  
Younghun Kim ◽  
Mi Seong Jo ◽  
...  
Keyword(s):  
Silica Nanoparticles ◽  
Amorphous Silica ◽  
Toxicity Study ◽  
Inhalation Toxicity ◽  
Sprague Dawley ◽  
Sprague Dawley Rats ◽  
Synthetic Amorphous Silica

Safety Assessment of a Hydroethanolic Extract of Caralluma fimbriata

2013 ◽  
Vol 32 (5) ◽  
pp. 385-394 ◽  
Author(s):  
Antoinette Y. Odendaal ◽  
Narendra S. Deshmukh ◽  
Tennille K. Marx ◽  
Alexander G. Schauss ◽  
John R. Endres ◽  
...  
Keyword(s):  
Developmental Toxicity ◽  
Toxicity Study ◽  
Developmental Study ◽  
Sprague Dawley ◽  
Oral Toxicity ◽  
Toxicological Assessment ◽  
Sprague Dawley Rats ◽  
Chromosomal Aberration Test ◽  
Hydroethanolic Extract

This toxicological assessment evaluated the safety of a hydroethanolic extract prepared from Caralluma fimbriata (CFE), a dietary supplement marketed worldwide as an appetite suppressant. Studies included 2 in vitro genotoxicity assays, a repeated dose oral toxicity study, and a developmental study in rats. No evidence of in vitro mutagenicity or clastogenicity surfaced in the in vitro studies at concentrations up to 5000 μg of extract/plate (Ames test) or 5000 μg of extract/mL (chromosomal aberration test). No deaths or treatment-related toxicity were seen in the 6-month chronic oral toxicity study in Sprague-Dawley rats conducted at 3 doses (100, 300, and 1000 mg/kg body weight (bw)/d). The no observed effect level for CFE in this study was considered to be 1000 mg/kg bw/d. A prenatal developmental toxicity study conducted at 3 doses (250, 500, and 1000 mg/kg bw/d) in female Sprague-Dawley rats resulted in no treatment-related external, visceral, or skeletal fetal abnormalities, and no treatment-related maternal or pregnancy alterations were seen at and up to the maximum dose tested. CFE was not associated with any toxicity or adverse events.

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