Genetic Epidemiology of Primary Congenital Glaucoma in the 22 Arab Countries: A Systematic Review

2021 ◽  
pp. 1-12
Author(s):  
Sara Jemmeih ◽  
Shaza Malik ◽  
Sarah Okashah ◽  
Hatem Zayed
2020 ◽  
Vol 20 (4) ◽  
pp. 275-285 ◽  
Author(s):  
Nadin Younes ◽  
Salma Younes ◽  
Ola. A. Alsharabasi ◽  
Mohamed E. El Zowalaty ◽  
Ibrahim Mustafa ◽  
...  

Celiac Disease (CD) is a complex immunogenic disease mainly triggered by gluten intake in genetically susceptible individuals with a prevalence of 1 in 100-300. CD results from the interplay between genetic and environmental factors. Genetic susceptibility is believed to play a prominent role in the pathogenicity of CD, mainly due to human leukocyte antigen (HLA)-related class II genes. Although CD is wellrecognized among Arab populations, there are few studies on the genetic epidemiology and prevalence of CD in the Arab countries. Therefore, the aim of this review was to highlight the importance of studying this disease in the Arab world in the context of a global perspective. Within the few studies published so far, it was found that Arab populations have a distinctive susceptibility genetic profile from other ethnic groups with the DQ2.5 and DQ8 genotypes that are considered the major genotypes that confer susceptibility among Arab patients with CD. Our findings will pave the way to perform further epidemiological studies that will help identify potential therapeutic targets against CD among Arab patients that are diagnosed with CD.


Author(s):  
Sedat Ava ◽  
Atılım Armağan Demirtaş ◽  
Mine Karahan ◽  
Seyfettin Erdem ◽  
Diclehan Oral ◽  
...  

2021 ◽  
pp. 112067212110104
Author(s):  
Mehmet Talay Koylu ◽  
Fatih Mehmet Mutlu ◽  
Alper Can Yilmaz

A 13-year-old female patient with refractory primary congenital glaucoma (PCG) in the right eye who had a history of multiple glaucoma operations underwent ab interno 180-degree trabeculectomy with the Kahook Dual Blade (KDB) targeting the nasal and inferior angles. On postoperative day 1, the intraocular pressure (IOP) of the right eye reduced from 43 to 15 mmHg while on medical therapy. The patient maintained this IOP level throughout the 6-month follow-up. Ab interno KDB trabeculectomy targeting both nasal and inferior angles may be an effective and safe procedure for the treatment of PCG even in eyes with a history of previously failed glaucoma procedures.


2013 ◽  
Vol 23 (3) ◽  
pp. 324-328 ◽  
Author(s):  
Tanuj Dada ◽  
Ashutosh Aggarwal ◽  
Shveta Jindal Bali ◽  
Meenakshi Wadhwani ◽  
Sana Tinwala ◽  
...  

2017 ◽  
Vol 88 (7) ◽  
pp. 540-549 ◽  
Author(s):  
Zhang-Yu Zou ◽  
Zhi-Rui Zhou ◽  
Chun-Hui Che ◽  
Chang-Yun Liu ◽  
Rao-Li He ◽  
...  

Eye ◽  
2018 ◽  
Vol 33 (4) ◽  
pp. 542-548 ◽  
Author(s):  
Sudarshan Khokhar ◽  
Dev Yadav ◽  
Shikha Gupta ◽  
Ramanjit Sihota ◽  
Abadh Kishore Chaurasia ◽  
...  

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