Infiltration of F98 glioma cells in Fischer rat brain is temporary stimulated by radiation

2016 ◽  
Vol 92 (8) ◽  
pp. 444-450 ◽  
Author(s):  
Guillaume Desmarais ◽  
Gabriel Charest ◽  
Hélène Therriault ◽  
Minghan Shi ◽  
David Fortin ◽  
...  
Keyword(s):  
1995 ◽  
Vol 62 (6) ◽  
pp. 767-771 ◽  
Author(s):  
Paal-Henning Pedersen ◽  
Klaus Eovardsen ◽  
Inmaculada Garcia-Cabrera ◽  
Rupavathana Mahesparan ◽  
Jon Thorsen ◽  
...  

2017 ◽  
Vol 39 (4) ◽  
pp. 258-263 ◽  
Author(s):  
L D Liubich ◽  
L M Kovalevska ◽  
M I Lisyany ◽  
V M Semenova ◽  
T A Malysheva ◽  
...  

The aim of the work was to study the impact of fetal rat brain cell supernatant (FRBCS) on the expression of transforming growth factor β1 (TGF-β1) and p53 in C6 cells of rat glioma in vitro. Materials and Methods: FRBCS was obtained from suspensions of fetal rat brain cells on the 14th (E14) day of gestation. C6 glioma cells were cultured for 48 h in the presence of FRBCS or FRBCS + anti-TGF-β1 monoclonal antibody. Immunocytochemical staining for TGF-β1 and p53 was performed. Results: The proportion of TGF-β1-immunopositive tumor cells in C6 glioma cultures was statistically significantly higher than in the control cell cultures of normal fetal rat brain. FRBCS reduced the proportion of TGF-β1-immunopositive tumor cells and increased the proportion of p53-immunopositive cells in C6 glioma cultures. In cells cultured with FRBCS + anti-TGF-β1 monoclonal antibody, the above effects of FRBCS were abrogated. Conclusion: The obtained results suggest that TGF-β1 seems to be responsible for decrease in TGF-β1 expression and increase in p53 expression in C6 glioma cells treated with FRBCS.


2008 ◽  
Vol 5 (3) ◽  
pp. 198-209 ◽  
Author(s):  
Hiroaki Namatame ◽  
Jiro Akimoto ◽  
Hiroyuki Matsumura ◽  
Jo Haraoka ◽  
Katsuo Aizawa

2009 ◽  
Vol 97 (2) ◽  
pp. 187-193 ◽  
Author(s):  
Gabriel Charest ◽  
Benoit Paquette ◽  
David Fortin ◽  
David Mathieu ◽  
Léon Sanche

1991 ◽  
Vol 10 (1) ◽  
pp. 13-25 ◽  
Author(s):  
Takanori Ohnishil ◽  
Peter B. Sher ◽  
Jerome B. Posner ◽  
William R. Shapiro ◽  
George C. Cotzias

1988 ◽  
Vol 16 (2) ◽  
pp. 212-213
Author(s):  
G. ERIC BLAIR ◽  
JADWIGA SAWECKA ◽  
SUSAN A. GRIFFITHS ◽  
MARIA E. BLAIR ZAJDEL

2002 ◽  
Vol 70 (1) ◽  
pp. 24-30 ◽  
Author(s):  
Martha C. Garcia ◽  
Glenn Ward ◽  
Yee-Chung Ma ◽  
Norman Salem ◽  
Hee-Yong Kim

The Analyst ◽  
2016 ◽  
Vol 141 (7) ◽  
pp. 2238-2249 ◽  
Author(s):  
Ibraheem Yousef ◽  
Olivier Seksek ◽  
Sílvia Gil ◽  
Yolanda Prezado ◽  
Josep Sulé-Suso ◽  
...  

One strategy to improve the clinical outcome of radiotherapy is to use nanoparticles as radiosensitizers.


1993 ◽  
Vol 86 (2) ◽  
pp. 117-125 ◽  
Author(s):  
Nobuhisa Nagano ◽  
Hiroshi Sasaki ◽  
Masaru Aoyagi ◽  
Kimiyoshi Hirakawa

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