The role of soluble receptor for advanced glycation end-products (sRAGE) in the general population and patients with diabetes mellitus with a focus on renal function and overall outcome

2020 ◽  
pp. 1-18
Author(s):  
Mieke Steenbeke ◽  
Sander De Bruyne ◽  
Marc De Buyzere ◽  
Bruno Lapauw ◽  
Reinhart Speeckaert ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Renal Function ◽  
General Population ◽  
Advanced Glycation End Products ◽  
Soluble Receptor ◽  
Advanced Glycation ◽  
Glycation End Products ◽  
End Products ◽  
Patients With Diabetes

Soluble Receptor for Advanced Glycation End Products in Patients With Decreased Renal Function

2006 ◽  
Vol 47 (3) ◽  
pp. 406-411 ◽  
Author(s):  
Marta Kalousová ◽  
Magdaléna Hodková ◽  
Markéta Kazderová ◽  
Jana Fialová ◽  
Vladimír Tesař ◽  
...  
Keyword(s):  
Renal Function ◽  
Advanced Glycation End Products ◽  
Soluble Receptor ◽  
Advanced Glycation ◽  
Glycation End Products ◽  
End Products

Role of soluble receptor for advanced glycation end products in postoperative fibrotic lung injury

2021 ◽  
Author(s):  
Satoshi Nakao ◽  
Kakuhiro Yamaguchi ◽  
Hiroshi Iwamoto ◽  
Atsushi Kagimoto ◽  
Takahiro Mimae ◽  
...  
Keyword(s):  
Lung Injury ◽  
Advanced Glycation End Products ◽  
Soluble Receptor ◽  
Advanced Glycation ◽  
Glycation End Products ◽  
End Products

Soluble receptor for advanced glycation end products and increased aortic stiffness in the general population

2015 ◽  
Vol 39 (4) ◽  
pp. 266-271 ◽  
Author(s):  
Otto Mayer ◽  
Jitka Seidlerová ◽  
Jan Filipovský ◽  
Petra Vágovičová ◽  
Peter Wohlfahrt ◽  
...  
Keyword(s):  
General Population ◽  
Advanced Glycation End Products ◽  
Aortic Stiffness ◽  
Soluble Receptor ◽  
Advanced Glycation ◽  
Glycation End Products ◽  
End Products

Role of methylglyoxal adducts in the development of vascular complications in diabetes mellitus

2003 ◽  
Vol 31 (6) ◽  
pp. 1400-1402 ◽  
Author(s):  
M. Bourajjaj ◽  
C.D.A. Stehouwer ◽  
V.W.M. van Hinsbergh ◽  
C.G. Schalkwijk
Keyword(s):  
Diabetes Mellitus ◽  
Advanced Glycation End Products ◽  
Vascular Complications ◽  
Advanced Glycation ◽  
Exact Role ◽  
Dicarbonyl Compound ◽  
Diabetic Vascular Complications ◽  
Glycation End Products ◽  
End Products

Various theories have been proposed to explain the hyperglycaemia-induced pathogenesis of vascular complications of diabetes, including detrimental effects of AGEs (advanced glycation end products) on vascular tissues. Increased formation of the very reactive dicarbonyl compound MGO (methylglyoxal), one of the side-products of glycolysis, and MGO-derived AGEs seem to be implicated in the development of diabetic vascular complications. Although the exact role of MGO and MGO adducts in the development of vascular complications is unknown, receptor-mediated activation of vascular cells by the MGO–arginine adduct hydroimidazolone, as well as intracellular modifications of protein by MGO, seem to be involved. The aim of this mini-review is to assess to what extent MGO is related to vascular complications in diabetes.

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