Gastro-protective effect of Artemisia sieberi essential oil against ethanol-induced ulcer in rats as revealed via biochemical, histopathological and metabolomics analysis

Biomarkers ◽  
2022 ◽  
pp. 1-45
Author(s):  
Naglaa M. Ammar ◽  
Heba Hassan ◽  
Rania Ahmed ◽  
Abd El-Nasser El Gendy ◽  
Ahmed Abd-ElGawad ◽  
...  
2018 ◽  
Vol 38 (5) ◽  
pp. 499-509 ◽  
Author(s):  
H Bouzenna ◽  
N Samout ◽  
S Dhibi ◽  
S Mbarki ◽  
S Akermi ◽  
...  

The present study is planned to examine the antioxidant activity (AA) and the protective effect of the essential oil of Citrus limon (EOC) against aspirin-induced histopathological changes in the brain, lung, and intestine of female rats. For this purpose, 28 albino rats were classified to control group (group C), aspirin group (group A), EOC group (group EOC), and pretreatment with EOC and treated with aspirin group (group EOC + A). The antioxidant activities of EOC were evaluated by three different assays including reducing power, β-carotene, and scavenging of hydrogen peroxide (H2O2). Our results found that EOC represents, respectively (0.064 ± 0.013 and 0.027 ± 00 mg Quer E/100 µL), of flavonoid and flavonol. Then, it exhibited a potential activity of reducing power (at 300 mg/mL, which was found to be 0.82 ± 0.07), β-carotene-linoleic acid (AA% = 69.28 ± 3.5%), and scavenging of H2O2 (IC50 = 0.23 ± 0.008 mg/mL). In vivo, aspirin given to rats at the dose of 600 mg/kg body weight induced histomorphological damage in brain, lung, and intestine. However, our data found that the pretreatment with EOC offered a significant protection against the injury induced by aspirin. It can be concluded that the protective effect of EOC can be due to its antioxidant activities.


2007 ◽  
Vol 10 (5) ◽  
pp. 810-813 ◽  
Author(s):  
R. Bagheri ◽  
M.R. Chaichi ◽  
M. Mohseni-S ◽  
G.R . Amin ◽  
G. Zahedi

2019 ◽  
Vol 27 (7) ◽  
pp. 945-951 ◽  
Author(s):  
Maged S. Abdel-Kader ◽  
Gamal A. Soliman ◽  
Mohammed H. Alqarni ◽  
Abubaker M. Hamad ◽  
Ahmed I. Foudah ◽  
...  

2020 ◽  
Vol 253 ◽  
pp. 112652 ◽  
Author(s):  
Jiali Chen ◽  
Cailin Tang ◽  
Rongfei Zhang ◽  
Shaoxia Ye ◽  
Zhimin Zhao ◽  
...  

2016 ◽  
Vol 19 (7) ◽  
pp. 1701-1708 ◽  
Author(s):  
Wenping Li ◽  
Fabrizio Papa ◽  
Jingshan Shi ◽  
Filippo Maggi ◽  
Xiuping Chen

2014 ◽  
Vol 210 (12) ◽  
pp. 1068-1074 ◽  
Author(s):  
Matheus D. Baldissera ◽  
Camila B. Oliveira ◽  
Virginia C. Rech ◽  
João F. Peres Rezer ◽  
Michele R. Sagrillo ◽  
...  

2016 ◽  
Vol 83 ◽  
pp. 1327-1334 ◽  
Author(s):  
Hafsia Bouzenna ◽  
Sabah Dhibi ◽  
Noura Samout ◽  
Ilhem Rjeibi ◽  
Hélène Talarmin ◽  
...  

2019 ◽  
Vol 15 (3) ◽  
pp. 222-232 ◽  
Author(s):  
Hua Zheng ◽  
Jinxia Wu ◽  
Hong Huang ◽  
Chunmei Meng ◽  
Weidong Li ◽  
...  

Diabetes is one of the most severe chronic diseases worldwide.


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