Vulnerability to early stressful life events: The moderating role of HOMER1 gene in the gene × environment interaction

2022 ◽  
pp. 1-23
Author(s):  
Yidi Chen ◽  
Lizhong Wang ◽  
Dongdong Jiang ◽  
Shanshan Zhu ◽  
WeGene Research Team ◽  
...  
Keyword(s):  
Life Events ◽  
Stressful Life Events ◽  
Stressful Life ◽  
Environment Interaction ◽  
Gene Environment Interaction ◽  
Gene Environment ◽  
Moderating Role

scholarly journals Vulnerability to depression: what is the role of stress genes in gene × environment interaction?

2009 ◽  
Vol 39 (9) ◽  
pp. 1407-1411 ◽  
Author(s):  
W. El Hage ◽  
J. F. Powell ◽  
S. A. Surguladze
Keyword(s):  
Life Events ◽  
Stressful Life Events ◽  
Environment Interaction ◽  
Stress Genes ◽  
Gene Environment Interaction ◽  
Gene Environment ◽  
Psychological Medicine ◽  
Response To Stress ◽  
Editorial Review

Vulnerability to depression has been linked to the interaction of genetic predisposition with stressful life events. This review considers the associations between serotonergic and hypothalamic–pituitary–adrenal (HPA) systems. We follow the standpoint of a previous Editorial Review (Bhagwagar & Cowen, Psychological Medicine 2008, 38, 307–313) and consider another possible mechanism of vulnerability to depressive disorder, that is we suggest that the gene×environment interaction involves complex participation of serotonergic genes modulating response to stress through the HPA system.

Overestimating self-blame for stressful life events and adolescents’ Latent Trait Cortisol (LTC): The moderating role of maternal warmth

2020 ◽  
Vol 119 ◽  
pp. 105005
Author(s):  
Catherine B. Stroud ◽  
Frances R. Chen ◽  
Blair Curzi ◽  
Douglas A. Granger ◽  
Leah D. Doane
Keyword(s):  
Life Events ◽  
Stressful Life Events ◽  
Latent Trait ◽  
Stressful Life ◽  
Maternal Warmth ◽  
Self Blame ◽  
Moderating Role
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