scholarly journals Clinical, laboratory features and prognosis of children receiving IgM-enriched immunoglobulin (3 days vs. 5 days) as adjuvant treatment for serious infectious disease in pediatric intensive care unit: a retrospective single-center experience (PIGMENT study)

2020 ◽  
Vol 16 (8) ◽  
pp. 1997-2002
Author(s):  
Emin Abdullayev ◽  
Omer Kilic ◽  
Gurkan Bozan ◽  
Eylem Kiral ◽  
Merve Iseri Nepesov ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Pediatric Intensive Care Unit ◽  
Adjuvant Treatment ◽  
Clinical Laboratory ◽  
Pediatric Intensive Care ◽  
Single Center ◽  
Single Center Experience ◽  
Laboratory Features

scholarly journals Clinical, laboratory, and radiological characteristics of COVID-19-infected children admitted to pediatric intensive care unit: a single-center experience

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Heba Mostafa Ahmed ◽  
Rehab Muhammad Abd El Kareem ◽  
Faten Mohamed Ali ◽  
Ahmed Reda Sayed ◽  
Yasmen Awadalh Mohamed
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Pediatric Intensive Care Unit ◽  
Clinical Laboratory ◽  
Pediatric Intensive Care ◽  
Laboratory Findings ◽  
Presenting Symptoms ◽  
Single Center Experience ◽  
Inflammatory Syndrome ◽  
Second Wave

Abstract Background During the second wave of COVID-19, there is an increasing incidence of reported cases in children compared to the early wave. Data on the clinical and laboratory characteristics of COVID-19 in children are evolving, and reports on the characteristics and outcomes of severe COVID-19 in children are still under evaluation. We aimed to describe the clinical, laboratory, and radiological characteristics and outcomes of children with COVID-19 infection admitted to the pediatric intensive care unit (PICU). Results The study included 27 children with COVID-19 infection. Fever, respiratory, and gastrointestinal (GIT) symptoms were predominant presenting symptoms in our patients. The median age of our patients was 9 months (2 m–12 years). Comorbidity was reported in 59.3%. The typical laboratory findings were leukocytosis, lymphopenia, elevated C-reactive proteins levels, and elevated d-dimer levels. The most frequent radiological findings were ground-glass opacities in 100% of patients and bilateral findings in 96%, while cardiomegaly was found in 44% of patients. The multisystem inflammatory syndrome was reported in 33% of patients with GIT symptoms were the most frequent presenting symptoms. Myocarditis was reported in 22% of patients. The mortality rate in this cohort was 14.8%. On multivariate analysis, the only predictor of mortality was the development of MIS-C. Conclusions COVID-19 is more severe in children with comorbid conditions. Fever, respiratory and gastrointestinal (GIT) symptoms were predominant presenting symptoms. MIS-C is of increasing concern in children with high mortality rates.

scholarly journals Non-Convulsive Status Epilepticus at Pediatric Intensive Care Unit: A Single Center Experience

2021 ◽  
pp. 1-6
Author(s):  
Omnia F El-Rashiedy ◽  
◽  
Hanan M Ibrahim ◽  
Rania H Shatla ◽  
◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Status Epilepticus ◽  
Pediatric Intensive Care Unit ◽  
Pediatric Intensive Care ◽  
Convulsive Status Epilepticus ◽  
Eeg Monitoring ◽  
Single Center Experience ◽  
Abnormal Movements ◽  
Observational Cohort

Objective: Our study aims to estimate the incidence of non-convulsive status epilepticus (NCSE) in comatose children and to evaluate response to acute treatment with anticonvulsants. Material and methods: This is a prospective observational cohort study conducted in Pediatric Intensive Care Unit (PICU) of Ain-Shams University. Eighty patients presented with Glasgow coma scale (GCS) <8 and/or the presence of abnormal movements or vital sign fluctuations were enrolled in the study. All were subjected to EEG monitoring for at least 1 hour within 24 hours of presentation. Patients diagnosed as NCSE received anticonvulsant treatment and were reevaluated clinically and by EEG after 1 week. Results: Twenty four patients were diagnosed as NCSE (30%). EEG was normalized in 50% of patients after treatment. Conclusion: NCSE is possible to be under-recognized in the PICU settings because of the pleomorphic clinical features. Clinical suspension of NCSE and EEG monitoring for critically ill comatose children will improve their outcome

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