Potential aetiologies and prognostic implications of worsening renal function in acute decompensated heart failure

2014 ◽  
Vol 69 (6) ◽  
pp. 657-663 ◽  
Author(s):  
Elsayed Abo-Salem ◽  
Khalid Sherif ◽  
Stephanie Dunlap ◽  
Sharma Prabhakar
Keyword(s):  
Heart Failure ◽  
Renal Function ◽  
Acute Decompensated Heart Failure ◽  
Decompensated Heart Failure ◽  
Worsening Renal Function ◽  
Prognostic Implications

scholarly journals Comparison between admission natriuretic peptides, NGAL and sST2 testing for the prediction of worsening renal function in patients with acutely decompensated heart failure

2015 ◽  
Vol 53 (4) ◽  
Author(s):  
Benedetta De Berardinis ◽  
Hanna K. Gaggin ◽  
Laura Magrini ◽  
Arianna Belcher ◽  
Benedetta Zancla ◽  
...  
Keyword(s):  
Heart Failure ◽  
Renal Function ◽  
Natriuretic Peptide ◽  
Acute Decompensated Heart Failure ◽  
International Study ◽  
Decompensated Heart Failure ◽  
Hospital Length Of Stay ◽  
Hospital Death ◽  
Amino Terminal ◽  
Worsening Renal Function

AbstractIn order to predict the occurrence of worsening renal function (WRF) and of WRF plus in-hospital death, 101 emergency department (ED) patients with acute decompensated heart failure (ADHF) were evaluated with testing for amino-terminal pro-B-type natriuretic peptide (NT-proBNP), BNP, sST2, and neutrophil gelatinase associated lipocalin (NGAL).In a prospective international study, biomarkers were collected at the time of admission; the occurrence of subsequent in hospital WRF was evaluated.In total 26% of patients developed WRF. Compared to patients without WRF, those with WRF had a longer in-hospital length of stay (LOS) (mean LOS 13.1±13.4 days vs. 4.8±3.7 days, p<0.001) and higher in-hospital mortality [6/26 (23%) vs. 2/75 (2.6%), p<0.001]. Among the biomarkers assessed, baseline NT-proBNP (4846 vs. 3024 pg/mL; p=0.04), BNP (609 vs. 435 pg/mL; p=0.05) and NGAL (234 vs. 174 pg/mL; p=0.05) were each higher in those who developed WRF. In logistic regression, the combination of elevated natriuretic peptide and NGAL were additively predictive for WRF (OR: In ED patients with ADHF, the combination of NT-proBNP or BNP plus NGAL at presentation may be useful to predict impending WRF (Clinicaltrials.gov NCT#0150153).

Worsening Renal Function in Patients Admitted with Acute Decompensated Heart Failure: Incidence, Predictors and Prognostic Value

2008 ◽  
Vol 14 (6) ◽  
pp. S91-S92
Author(s):  
Cesar A. Belziti ◽  
Ledezma Paola ◽  
Bagnati P. Rodrigo ◽  
Vulcano Norberto ◽  
Fernandez Sandra
Keyword(s):  
Heart Failure ◽  
Renal Function ◽  
Prognostic Value ◽  
Acute Decompensated Heart Failure ◽  
Decompensated Heart Failure ◽  
Worsening Renal Function

Effect and Clinical Prediction of Worsening Renal Function in Acute Decompensated Heart Failure

2011 ◽  
Vol 107 (5) ◽  
pp. 730-735 ◽  
Author(s):  
Tobias Breidthardt ◽  
Thenral Socrates ◽  
Markus Noveanu ◽  
Theresia Klima ◽  
Corinna Heinisch ◽  
...  
Keyword(s):  
Heart Failure ◽  
Renal Function ◽  
Acute Decompensated Heart Failure ◽  
Decompensated Heart Failure ◽  
Clinical Prediction ◽  
Worsening Renal Function
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