Pandemic Influenza A(H1N1)2009 in Hospital Healthcare Workers in New Zealand

2012 ◽  
Vol 33 (2) ◽  
pp. 196-199 ◽  
Author(s):  
Nigel J. Raymond ◽  
Neville Berry ◽  
Tim K. Blackmore ◽  
Sarah Jefferies ◽  
Katherine Norton ◽  
...  
Keyword(s):  
New Zealand ◽  
Pandemic Influenza ◽  
Healthcare Workers ◽  
Influenza A ◽  
H1n1 Influenza ◽  
Rapid Diagnosis ◽  
Infect Control Hosp ◽  
Diagnosis And Treatment ◽  
Influenza A H1n1

We evaluated A/H1N1 influenza in healthcare workers (HCWs) and in a flu room during the 2009 pandemic. The flu room aided HCW care and management by facilitating rapid diagnosis and treatment. Absence of fever was common, and symptoms were nonspecific. A higher rate of H1N1 occurred in HCWs deployed in acute services.Infect Control Hosp Epidemiol2012;33(2):196-199

scholarly journals Effectiveness of the 2009 seasonal influenza vaccine against pandemic influenza A(H1N1)2009 in healthcare workers in New Zealand, June-August 2009

2011 ◽  
Vol 16 (2) ◽  
Author(s):  
S Jefferies ◽  
D Earl ◽  
N Berry ◽  
T Blackmore ◽  
S Rooker ◽  
...  
Keyword(s):  
New Zealand ◽  
Influenza Vaccine ◽  
Pandemic Influenza ◽  
Healthcare Workers ◽  
Influenza A ◽  
Seasonal Influenza ◽  
Seasonal Influenza Vaccine ◽  
Binary File ◽  
Influenza A H1n1

Binary file ES_Abstracts_Final_ECDC.txt matches

scholarly journals Pandemic influenza A(H1N1)pdm09: risk of infection in primary healthcare workers

2013 ◽  
Vol 63 (611) ◽  
pp. e416-e422 ◽  
Author(s):  
Ben Hudson ◽  
Les Toop ◽  
Dee Mangin ◽  
Cheryl Brunton ◽  
Lance Jennings ◽  
...  
Keyword(s):  
Primary Healthcare ◽  
Pandemic Influenza ◽  
Healthcare Workers ◽  
Influenza A ◽  
Risk Of Infection ◽  
Influenza A H1n1

scholarly journals Contemporary Seasonal Influenza A (H1N1) Virus Infection Primes for a More Robust Response To Split Inactivated Pandemic Influenza A (H1N1) Virus Vaccination in Ferrets

2010 ◽  
Vol 17 (12) ◽  
pp. 1998-2006 ◽  
Author(s):  
Ali H. Ellebedy ◽  
Thomas P. Fabrizio ◽  
Ghazi Kayali ◽  
Thomas H. Oguin ◽  
Scott A. Brown ◽  
...  
Keyword(s):  
Influenza Virus ◽  
Pandemic Influenza ◽  
Influenza A ◽  
Seasonal Influenza ◽  
H1n1 Virus ◽  
H1n1 Influenza ◽  
Influenza Viruses ◽  
Inactivated Vaccine ◽  
H1n1 Influenza Virus ◽  
Influenza A H1n1

ABSTRACT Human influenza pandemics occur when influenza viruses to which the population has little or no immunity emerge and acquire the ability to achieve human-to-human transmission. In April 2009, cases of a novel H1N1 influenza virus in children in the southwestern United States were reported. It was retrospectively shown that these cases represented the spread of this virus from an ongoing outbreak in Mexico. The emergence of the pandemic led to a number of national vaccination programs. Surprisingly, early human clinical trial data have shown that a single dose of nonadjuvanted pandemic influenza A (H1N1) 2009 monovalent inactivated vaccine (pMIV) has led to a seroprotective response in a majority of individuals, despite earlier studies showing a lack of cross-reactivity between seasonal and pandemic H1N1 viruses. Here we show that previous exposure to a contemporary seasonal H1N1 influenza virus and to a lesser degree a seasonal influenza virus trivalent inactivated vaccine is able to prime for a higher antibody response after a subsequent dose of pMIV in ferrets. The more protective response was partially dependent on the presence of CD8+ cells. Two doses of pMIV were also able to induce a detectable antibody response that provided protection from subsequent challenge. These data show that previous infection with seasonal H1N1 influenza viruses likely explains the requirement for only a single dose of pMIV in adults and that vaccination campaigns with the current pandemic influenza vaccines should reduce viral burden and disease severity in humans.

scholarly journals Clinical impact of influenza – lessons learnt from the pandemic influenza A (H1N1) 2009

2011 ◽  
Vol 32 (1) ◽  
pp. 29
Author(s):  
Alex Dierig ◽  
Gulam Khandaker ◽  
Robert Booy
Keyword(s):  
Clinical Features ◽  
Pandemic Influenza ◽  
Influenza A ◽  
Influenza Pandemic ◽  
Gastrointestinal Symptoms ◽  
H1n1 Influenza ◽  
World Health ◽  
Pandemic H1n1 ◽  
Pandemic H1n1 Influenza ◽  
Influenza A H1n1

Influenza is generally an acute, self-limiting, febrile illness without further complications in the majority of people. However, it can be associated with severe morbidity and mortality and the burden of the disease on society is likely to be underestimated. In 2009 an outbreak of H1N1 influenza A virus infection was detected in Mexico with further cases soon observed worldwide. Subsequently, in June 2009, the first influenza pandemic of the 21st century due to influenza A (H1N1) was declared by the World Health Organization (WHO). There were many uncertainties regarding the virulence, clinical symptoms and epidemiological features of this newly evolved influenza A strain. Over time, many similarities, but also some differences between the pandemic H1N1 influenza A and seasonal influenza were identified. We recently performed a systematic review of the literature, looking at articles published between 1 April 2009 and 31 January 2010, to identify the epidemiological and clinical features of the pandemic H1N1 influenza. In this current article we compare our findings with others from the international literature. There was more severe impact on young and healthy adults, children, pregnant women and the obese. Clinical features in general were similar between seasonal and pandemic influenza; however, there were more gastrointestinal symptoms associated with pandemic H1N1 influenza. Shortness of breath was characteristic of more severe pH1N1 2009 infection with a higher possibility of being admitted to an intensive care unit (ICU).

scholarly journals Transmissibility of 2009 pandemic influenza A(H1N1) in New Zealand: effective reproduction number and influence of age, ethnicity and importations

2010 ◽  
Vol 15 (24) ◽  
Author(s):  
S Paine ◽  
G N Mercer ◽  
P M Kelly ◽  
D Bandaranayake ◽  
M G Baker ◽  
...  
Keyword(s):  
New Zealand ◽  
Pandemic Influenza ◽  
Influenza A ◽  
Reproduction Number ◽  
Binary File ◽  
Influenza A H1n1

Binary file ES_Abstracts_Final_ECDC.txt matches

scholarly journals Pandemic influenza A(H1N1)v in New Zealand: the experience from April to August 2009

2009 ◽  
Vol 14 (34) ◽  
Author(s):  
M G Baker ◽  
N Wilson ◽  
Q S Huang ◽  
S Paine ◽  
L Lopez ◽  
...  
Keyword(s):  
New Zealand ◽  
Pandemic Influenza ◽  
Influenza A ◽  
Binary File ◽  
Influenza A H1n1

Binary file ES_Abstracts_Final_ECDC.txt matches

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