scholarly journals THE ROLE OF FAST MAGNETOSONIC WAVES IN THE RELEASE AND CONVERSION VIA RECONNECTION OF ENERGY STORED BY A CURRENT SHEET

2012 ◽  
Vol 756 (2) ◽  
pp. 192 ◽  
Author(s):  
D. W. Longcope ◽  
L. Tarr
Keyword(s):  
Current Sheet ◽  
A Current

scholarly journals Resistive Processes in the Preflare Phase of Eruptive Flares

1998 ◽  
Vol 188 ◽  
pp. 207-208
Author(s):  
T. Magara ◽  
K. Shibata
Keyword(s):  
Current Sheet ◽  
Current Density ◽  
Solar Flares ◽  
Magnetic Pressure ◽  
Anomalous Resistivity ◽  
Magnetic Island ◽  
Tearing Instability ◽  
Mhd Simulations ◽  
A Current

In this study, we perform 2.5-dimensional MHD simulations and clarify the role of perpendicular magnetic fields (which are perpendicular to the 2D plane) in a preflare current sheet of solar flares. At the first stage, a current sheet formed within a coronal magnetic structure is filled with the perpendicular fields (force-free structure). Then this sheet begins to be dissipated through the tearing instability under a uniform resistivity. As the instability proceeds, the distribution of the perpendicular fields vary in such a way that most of them gather around O-point (magnetic island) instead of X-point. Therefore, the magnetic pressure of these fields weaken in the vicinity of X-point so that they no longer suppress the inflows toward this point. These flows then make the current sheet thinner and thinner, which implies that the current density around X-point becomes high enough to cause an anomalous resistivity whose value is much larger than that of the normal collisional resistivity. In this way, the transition from a uniform resistivity to a locally-enhanced one occurs, which can make the violent energy release observed in solar flares.

Role of Regulatory Acts in Creation of a Democratic State

2020 ◽  
pp. 82-86
Author(s):  
R. F.o. Veliev
Keyword(s):  
Russian Federation ◽  
Legal Norm ◽  
Legal Basis ◽  
Democratic State ◽  
The Russian Federation ◽  
A Current

A current theoretical and practical legal basis for creation of regulatory acts in the Russian Federation is discussed. A current relationship between the issued regulatory acts and some criteria of legal norm classification is shown. Legalization of the President address to the Parliament of the Russian Federation as a substantial element of the legal norm-making in a democratic state is revealed.

Audit Reviewers' Judgments in Multiple Client Audit Environments

2017 ◽  
Vol 29 (2) ◽  
pp. 1-9 ◽  
Author(s):  
Sudip Bhattacharjee ◽  
Mario J. Maletta ◽  
Kimberly K. Moreno
Keyword(s):  
Audit Quality ◽  
Internal Audit ◽  
Contrast Effects ◽  
Comparative Information ◽  
A Current

ABSTRACT This study replicates Bhattacharjee, Maletta, and Moreno (2007), who find that audit preparers are susceptible to contrast effects in a multi-client environment. We demonstrate that auditors in the role of reviewers are also susceptible to contrast effects from a prior client. Audit reviewers' assessments of internal audit quality of a current client were significantly affected by the quality of the internal audit group of a client they previously reviewed. Specifically, when auditors first reviewed a client with a weak internal audit group they assessed the subsequent moderate internal audit group as being of higher quality than when they first reviewed a prior client with a strong internal audit group or did not review a prior client. Reviewers' documentation of evidence was also influenced by comparative information from the prior client. These results corroborate the key findings of Bhattacharjee et al. (2007) and confirm audit reviewers' susceptibility to contrast effects.

Magnesium and Hearing

2003 ◽  
Vol 14 (04) ◽  
pp. 202-212 ◽  
Author(s):  
Michael J. Cevette ◽  
Jürgen Vormann ◽  
Kay Franz
Keyword(s):  
Hair Cells ◽  
Auditory Nerve ◽  
Mg Deficiency ◽  
Noise Damage ◽  
Susceptibility To Noise ◽  
Major Progress ◽  
A Current ◽  
Putative Mechanism ◽  
Increased Susceptibility

The last several decades have revealed clinical and experimental data regarding the importance of magnesium (Mg) in hearing. Increased susceptibility to noise damage, ototoxicity, and auditory hyperexcitibility are linked to states of Mg deficiency. Evidence for these processes has come slowly and direct effects have remained elusive because plasma Mg levels do not always correlate with its deficiency. Despite the major progress in the understanding of cochlear mechanical and auditory nerve function, the neurochemical and pharmacologic role of Mg is not clear. The putative mechanism suggests that Mg deficiency may contribute to a metabolic cellular cascade of events. Mg deficiency leads to an increased permeability of the calcium channel in the hair cells with a consequent over influx of calcium, an increased release of glutamate via exocytosis, and over stimulation of NMDA receptors on the auditory nerve. This paper provides a current overview of relevant Mg metabolism and deficiency and its influence on hearing.

scholarly journals Role of Bradykinin Type 2 Receptors in Human Sweat Secretion: Translational Evidence Does Not Support a Functional Relationship

2021 ◽  
Vol 34 (3) ◽  
pp. 162-166
Author(s):  
Thad E. Wilson ◽  
Seetharam Narra ◽  
Kristen Metzler-Wilson ◽  
Artur Schneider ◽  
Kelsey A. Bullens ◽  
...  
Keyword(s):  
Healthy Subjects ◽  
Sweat Rate ◽  
Sweat Glands ◽  
Potential Therapeutic Target ◽  
Sweat Secretion ◽  
Hoe 140 ◽  
A Current

Bradykinin increases skin blood flow via a cGMP mechanism but its role in sweating in vivo is unclear. There is a current need to translate cell culture and nonhuman paw pad studies into in vivo human preparations to test for therapeutic viability for disorders affecting sweat glands. Protocol 1: physiological sweating was induced in 10 healthy subjects via perfusing warm (46–48°C) water through a tube-lined suit while bradykinin type 2 receptor (B2R) antagonist (HOE-140; 40 μM) and only the vehicle (lactated Ringer’s) were perfused intradermally via microdialysis. Heat stress increased sweat rate (HOE-140 = +0.79 ± 0.12 and vehicle = +0.64 ± 0.10 mg/cm<sup>2</sup>/min), but no differences were noted with B2R antagonism. Protocol 2: pharmacological sweating was induced in 6 healthy subjects via intradermally perfusing pilocarpine (1.67 mg/mL) followed by the same B2R antagonist approach. Pilocarpine increased sweating (HOE-140 = +0.38 ± 0.16 and vehicle = +0.32 ± 0.12 mg/cm<sup>2</sup>/min); again no differences were observed with B2R antagonism. Last, 5 additional subjects were recruited for various control experiments which identified that a functional dose of HOE-140 was utilized and it was not sudorific during normothermic conditions. These data indicate B2R antagonists do not modulate physiologically or pharmacologically induced eccrine secretion volumes. Thus, B2R agonist/antagonist development as a potential therapeutic target for hypo- and hyperhidrosis appears unwarranted.

Estimation of electromagnetic field in air by a magnetic dipole in the sea based on a current sheet model

2016 ◽  
Vol 10 (7) ◽  
pp. 709-718
Author(s):  
Honglei Wang ◽  
Kunde Yang ◽  
Kun Zheng ◽  
Yixin Yang ◽  
Yuanliang Ma
Keyword(s):  
Electromagnetic Field ◽  
Current Sheet ◽  
Magnetic Dipole ◽  
A Current

scholarly journals Heterokairy: a significant form of developmental plasticity?

2016 ◽  
Vol 12 (9) ◽  
pp. 20160509 ◽  
Author(s):  
S. D. Rundle ◽  
J. I. Spicer
Keyword(s):  
Research Agenda ◽  
Developmental Plasticity ◽  
Potential Role ◽  
Research Effort ◽  
Adaptive Significance ◽  
Research Interest ◽  
Adaptive Plasticity ◽  
Comparative Embryology ◽  
A Current

There is a current surge of research interest in the potential role of developmental plasticity in adaptation and evolution. Here we make a case that some of this research effort should explore the adaptive significance of heterokairy, a specific type of plasticity that describes environmentally driven, altered timing of development within a species. This emphasis seems warranted given the pervasive occurrence of heterochrony, altered developmental timing between species, in evolution. We briefly review studies investigating heterochrony within an adaptive context across animal taxa, including examples that explore links between heterokairy and heterochrony. We then outline how sequence heterokairy could be included within the research agenda for developmental plasticity. We suggest that the study of heterokairy may be particularly pertinent in (i) determining the importance of non-adaptive plasticity, and (ii) embedding concepts from comparative embryology such as developmental modularity and disassociation within a developmental plasticity framework.

scholarly journals Heparin-induced thrombocytopenia: research and clinical updates

Hematology ◽  
2016 ◽  
Vol 2016 (1) ◽  
pp. 262-268 ◽  
Author(s):  
Oluwatoyosi Onwuemene ◽  
Gowthami M. Arepally
Keyword(s):  
Limited Data ◽  
Platelet Factor ◽  
Heparin Induced Thrombocytopenia ◽  
Diagnostic Strategies ◽  
Immune Mediated ◽  
Emerging Therapies ◽  
Current Perspective ◽  
Clinical Advances ◽  
A Current

Abstract Heparin-induced thrombocytopenia (HIT) remains an important diagnosis to consider in hospitalized patients developing thrombocytopenia. HIT is an immune-mediated prothrombotic disorder caused by antibodies to platelet factor 4 (PF4) and heparin. Recent basic scientific studies have advanced our understanding of disease pathogenesis through studies of the PF4/heparin structure, immune mechanisms, and cellular basis of thrombosis. Clinical advances have also occurred in areas of HIT prevention, description of disease variants, and diagnostic strategies. Emerging anticoagulants with the potential to change HIT treatment are evolving, although with limited data. This review will provide a current perspective on HIT pathogenesis, disease features, diagnostic strategies, and role of emerging therapies for the management of HIT.

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