scholarly journals The development of a functional adaptogenic beverage, using plant extracts of Centella asiatica and Hoodia gordonii

2021 ◽  
Vol 640 (2) ◽  
pp. 022092
Author(s):  
A R Khasanov ◽  
N A Matveeva ◽  
A A Gruzd
2015 ◽  
Vol 10 (11) ◽  
pp. 1934578X1501001 ◽  
Author(s):  
Caihui Wang ◽  
Wen Su ◽  
Xingli Su ◽  
Guojun Ni ◽  
Tao Liu ◽  
...  

The gastric mucosa protection effect of three natural plant extracts, Hericium erinaceus (HE), Centella asiatica (CA) and Amomum villosum (AV), were evaluated using the indomethacin damage model. Compared with a single extract, a combination of HE/CA/AV, especially with the ratios of 80:10:10, 45:45:10 and 45:10:45, showed significant synergistic effects for protection of the gastric mucosa with gastric ulcer inhibition rates of 97.8 ± 0.7%, 86.5 ± 2.8% and 86.1 ± 3.6%, respectively. Microscopic appearances of the gastric mucosa were carried out to help confirm the results.


Author(s):  
Arky Jane Langstieh ◽  
Julie Birdie Wahlang ◽  
Clarissa Jane Lyngdoh ◽  
Ibaphylla Jaba ◽  
Chayna Sarkar ◽  
...  

Flavonoids are secondary plant metabolites normally found as pigmented compounds in plants. Quercetin and rutin are two important and commonly found flavonoids in nature and exhibit wide pharmacological effects such as antioxidant, anticarcinogenic, antiviral, anti-inflammatory, antidiabetic, and hepatoprotective activities as well as antimicrobial activity. In this study, quercetin and rutin content is being quantified in the plant extracts of Centella asiatica and Houttuynia cordata and considerable amounts of these two flavonoids were depicted. A single beam UV – Spectrophotometer was used to measure the absorbance of the standard as well as test solutions. Calibration curves were constructed for standard quercetin and rutin in such a way that x-axis denotes concentration and the y-axis denotes the absorbance. The calibration curves showed linearity at concentrations 5-25 ?g /ml of quercetin and rutin respectively with a good correlation coefficient (r) of 0.99 for both the curves. The absorbance of the two test extracts was obtained from the calibration curve and respective concentrations of quercetin and rutin for the two extracts were calculated. The amount of quercetin and rutin present was expressed as Total Flavonoid Content (TFC) i.e. the amount of the flavonoid in ?g present per mg of the respective plant extract. The quercetin content in both the plant extracts was found to be more (315.8 in Houttuynia cordata; 487.6 in Centella asiatica) than the content of rutin (152.2 in Houttuynia cordata; 171.0 in Centella asiatica).


2018 ◽  
Vol 6 (5) ◽  
pp. 16-25
Author(s):  
Anoja Priyadarshani Attanayake ◽  
Kamani Ayoma Perera Wijewardana Jayatilaka

The objectives of the study were to determine the acetylcholinesterase (AChE) inhibitory activity and antioxidant activity in the selected Sri Lankan medicinal plants. AChE inhibitory activity of the selected medicinal plant extracts was determined using the Ellman’s method. The antioxidant activities were determined by four in vitro methods namely DPPH assay, FRAP assay, NO assay and TBA acid method.  The contents of total polyphenols and flavonoids were determined quantitatively.Out of the ten selected medicinal plant extracts Abrus precatorius, Centella asiatica, Strychnos nux-vomica and Ricinus communis showed IC50 values < 200 µg/mL for AChE inhibitory activity. A high antioxidant activity was shown in the extracts of Cardiosprmum halicacabum, Centella asiatica and  Ricinus communis in  the four selected antioxidant assays.  The total polyphenol content and total flavonoid content was in the range of 0.55-7.30 mg/g DW and 19.08±0.29-1283.08± 0.09 µg/gDW. The extracts of A. precatorius, C. asiatica, S. nux-vomica and R. communis are deserved to be as potent sources of AChE inhibitors as well as natural antioxidants. Considering the complex multifactorial etiology of Alzheimer's diseases, these plant extracts would be apt candidates for the development of novel pharmaceutical agents in the management of Alzheimer's diseases.  


2012 ◽  
Vol 2012 ◽  
pp. 1-13 ◽  
Author(s):  
M. Shyamala ◽  
P. K. Kasthuri

The Inhibitive action of the extracts ofAdathoda vasica, Eclipta alba,andCentella asiaticaon the corrosion of mild steel in 1N HCl has been studied using weight loss method, electrochemical methods, and hydrogen permeation method. Polarization method indicates that the plant extracts are under mixed control, that is, promoting retardation of both anodic and cathodic reactions. The impedance method reveals that charge-transfer process controls the corrosion of mild steel. The plant extracts obey Langmuir adsorption isotherm. Theoretical fitting of the corrosion data to the kinetic-thermodynamic model was tested to show the nature of adsorption. Physisorption mechanism has been proposed for the inhibition action of these plant extracts. The protective film formed on the surface was confirmed by SEM. From hydrogen permeation method, all the plant extracts were able to reduce the permeation current. Results obtained in all three methods were very much in good agreement in the orderEclipta alba > Adathoda vasica > Centella asiatica,and, among the three plant extracts studied, the maximum inhibition efficiency was found inEclipta albawhich showed 99.6% inhibition efficiency at 8.0% v/v concentration of the extract.


2018 ◽  
Vol 3 (4) ◽  
pp. 405-411
Author(s):  
Md Mizanur Rahman ◽  
Md Raquib Shahriar ◽  
Nigar Sultana Meghla ◽  
Tasneema Ishika ◽  
Pravas Chandra Roy ◽  
...  

Antibacterial active compounds isolated from higher plants appear to be one of the most important alternative approaches to contain antibiotic resistance and the management of disease. The present study was aimed at to investigate the antibacterial activity of some medicinal plant species including seeds namely Centella asiatica, Oxalis corniculata, Phoenix dactylifera, Clitoria ternatea and Nigella sativa. The methanolic and ethanolic extract of Centella asiatica, Oxalis corniculata, Phoenix dactylifera and Clitoria ternatea was investigated for antimicrobial activity at different concentrations by using disc diffusion method against some bacterial strains with standard antibiotic cephachlore (10 μg). The result demonstrated that all the extracts showed antibacterial activities against the isolates, which were dose dependent. The ethanolic extract of Oxalis corniculata at a concentration of 50 μl/disc had the highest effect on the test organism B. subtilis, Salmonella typhi and E. coli with 9.3, 9.7 and 10.8 mm diameter of zone of inhibition respectively while at the same concentration the extract of Clitoria ternatea had a higher antimicrobial activity on Bacillus cereus with 11.3 mm diameter of zone of inhibition. The activities of the plant extracts on the tested pathogens were not as effective as the standard commercial antibacterial disc but was significant. In case of Nigella sativa, Pseudomonas aeruginosa was sensitive to both the ethanolic extract and oils at different concentration. Salmonella typhi shows the same degree of inhibition for ethanolic extract as Bacillus cereus, but greater inhibition for oils. Of all the bacteria, Pseudomonas aeruginosa was the most sensitive bacteria against ethanolic extract and oils, while Bacillus cereus was the most resistant bacteria. Generally, the oils of Nigella sativa sample had higher antibacterial activity against bacteria than ethanolic extract. All the extracts are inhibitory to most common human pathogen S. typhi. The results suggest that the different plant extracts has a significant scope to develop a novel broad spectrum of antibacterial herbal formulations.Asian J. Med. Biol. Res. December 2017, 3(4): 405-411


Author(s):  
KARINA O. WISEVA ◽  
FRIDA WIDYASTUTI ◽  
HISA FAADHILAH ◽  
NASRUL WATHONI

This review conducted to compare the difference of the formulation of nanoemulsion cosmetics by plant extracts between Centella asiatica, seed oil from Rubus idaeus, Phyllanthus urinaria, Garcinia mangostana L., Vellozia sauamata, and Cordyceps militaris extract. Materials and methods was taken from several literature in valid databases that focuses on current status of the formulation of nanoemulsion and its characteristics, nanoemulsion cosmetics, and formulation of nanoemulsion cosmetics that are made by plant extract as the active ingredient. Comparison of the formulas above can be seen from various aspects. Referring to each article, 4 out of 6 formulas use high energy techniques and the rest use low energy techniques. Formula 1, 3, 6 use high energy technique with high pressure homogenization, and formula 4 uses ultrasonication, which is still a high energy technique. Formulas 2 and 5 use low energy techniques, namely formula 2 using Phase Inversion Composition (PIC) and formula 5 using Phase Inversion Temperature (PIT). High-Pressure Homogenizer (HPH) is the most widely used for the manufacture of nanoemulsions. In terms of formula, the use of components such as surfactant, cosurfactant, oil phase, and water phase is also different from the 6 formulas presented. Even though all of the six formulas are different, the active ingredients in the form of nanoemulsions need to be tested until finally the goal of the cosmetic product is achieved.


2021 ◽  
Vol 8 (3) ◽  
Author(s):  
Mohammad Hoesain ◽  
Sigit Prastowo ◽  
Wagiyana ◽  
Ankardiansyah Pandu Pradana ◽  
Fariz Kustiawan Alfarisy ◽  
...  

Profenofos is an active ingredient from the organophosphate group which residue is often found in various fresh and processed vegetable products. This study aimed to assess the use of aqueous plant extracts of Sapindus rarak seeds, Luffa acutangula peel and Centella asiatica leaves to reduce profenofos residues in leaf of mustard and to evaluate their performance in suppressing the grasshopper populations. S. rarak seeds, L. acutangula peels and C. asiatica leaves were dried and filtered using a 100 mesh sieve. A total of 30 gm samples of each ingredient were mixed with 1000 ml of water and blended at 800 rpm, then filtered using 100 mesh sieve before use. The field experiment was performed by spraying profenofos pesticide with a concentration of 3 ml l-1 at a dose of 30 ml per plant. Two days after the profenofos application, the plants were sprayed with the aqueous plant extracts. Twenty-four hrs aqueous plant extracts application, pesticide residues were detected by the UPLC-MS/MS machine. The phytotoxicity test results showed that the use of aqueous plant extracts at a dose of 30 ml per plant did not cause any phytotoxic symptoms. Furthermore, in the field experiment, the control plants showed a residual value of 2407.62 ng g-1. Results of UPLC-MS/MS showed that the residual value of profenofos in PL treatment (aqueous extract of S. rarak seeds) was 1502.05 ng g-1, the recorded residual value in the PP treatment (aqueous extract of C. asiatica leaves) was 1316.27 ng g-1 and the residual value in the PG treatment (aqueous extract of L. acutangula peels) was 660.71 ng g-1. In the treated plants, the residual value decreased from 37.48% to 72.55%. Furthermore, the number of grasshoppers after the PL treatment decreased and was significantly different from the control. This study provides new information that aqueous plant extracts can reduce the residue of profenofos and suppress the population of grasshoppers in the mustard leaf.


2016 ◽  
Vol 14 (1) ◽  
pp. 7-12
Author(s):  
MM Islam ◽  
MS Monjil

Aqueous extract of some indigenous plant parts were evaluated for its efficacy to control sheath blight of rice. Six treatments were applied, viz. T1- control (water spray), T2- Tulsi (Ocientific tenuiflorum) extract (1:10), T3- Nishinda (Vitex negundu) extract (1:10), T4- Thankuni (Centella asiatica) extracts (1:10), T5- Biskatali (Polygonum hydropiper) extract (1:10) and T6- Proud (Propiconazole @ 0.2%) as a positive control. Effect of these plant extracts on percent tiller infection and percent relative lesion height of sheath blight of rice cultivar BRRI dhan 49 was determined at 55, 75 and 95 day after transplanting (DAT). Number of infected tillers per hill differed significantly among the different treatments. The highest number of infected tillers was observed in control treatment. The lowest and statistically similar number of infected tillers was found in fungicide, Proud (Propiconazole)- and Biskatali- treated plots. Reduced number of infected tillers was observed in Tulsi, Thankuni and Nishinda. Highest percent tiller infection was recorded in control and lowest percent tiller infection was recorded in Proud and Biskatali, which were statistically similar. Nishinda, Tulsi and Thankuni had reduced tiller infection in compare to control. Percent reduction of tiller infection over control was achieved by proud followed by Biskatali. The highest lesion height was observed in control and lowest lesion height was found in Proud followed by Biskatali. The highest percent relative lesion height was recorded in control followed by Thankuni. The lowest percent relative lesion height was recorded in Proud preceded by Biskatali. Highest percent reduction of relative lesion height over control was achieved by proud followed by Biskatali. Thus, plant extracts of Biskatali, Tulsi, Nishinda and Thankuni are effective to control sheath blight of rice. Among the plant extracts, Biskatali showed highest control of sheath blight disease of rice.J. Bangladesh Agril. Univ. 14(1): 7-12, June 2016


Fruits ◽  
2009 ◽  
Vol 64 (5) ◽  
pp. 285-294 ◽  
Author(s):  
Sissay B. Mekbib ◽  
Thierry J.C. Regnier ◽  
Dharini Sivakumar ◽  
Lise Korsten

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