scholarly journals INFLUENCE OF PRENATAL ALCOHOL EXPOSURE ON MYOCARDIAL CONTRACTILE FUNCTION IN ADULT RAT HEARTS: ROLE OF INTRACELLULAR CALCIUM AND APOPTOSIS

2002 ◽  
Vol 37 (1) ◽  
pp. 30-37 ◽  
Author(s):  
J. Ren
Keyword(s):  
Intracellular Calcium ◽  
Contractile Function ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Adult Rat ◽  
Rat Hearts ◽  
Myocardial Contractile ◽  
Prenatal Alcohol

scholarly journals Role of corticosterone in anxiety- and depressive-like behavior and HPA regulation following prenatal alcohol exposure

2019 ◽  
Vol 90 ◽  
pp. 1-15
Author(s):  
Vivian Y.Y. Lam ◽  
Charlis Raineki ◽  
Lisa Y. Wang ◽  
Melissa Chiu ◽  
Grace Lee ◽  
...  
Keyword(s):  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Prenatal Alcohol

Downregulation of ventricular contractile function during early ischemia is flow but not pressure dependent

1998 ◽  
Vol 275 (5) ◽  
pp. H1520-H1523 ◽  
Author(s):  
Miao-Xiang He ◽  
H. Fred Downey
Keyword(s):  
Coronary Artery ◽  
Perfusion Pressure ◽  
Contractile Function ◽  
Coronary Perfusion Pressure ◽  
Coronary Perfusion ◽  
Rat Hearts ◽  
Myocardial Contractile Force ◽  
Myocardial Contractile ◽  
Artery Obstruction

The mechanism responsible for the abrupt fall in myocardial contractile function following coronary artery obstruction is unknown. The “vascular collapse theory” hypothesizes that the fall in coronary perfusion pressure after coronary artery obstruction is responsible for contractile failure during early ischemia. To test the role of vascular collapse in downregulating myocardial contractile force at the onset of ischemia, coronary flow of isolated rat hearts was abruptly decreased by 50, 70, 85, and 100% of baseline, and subsequent changes in coronary perfusion pressure and ventricular function were recorded at 0.5-s intervals. At 1.5 s after flow reductions ranging from 50 to 100%, decreases in contractile function did not differ, although perfusion pressure varied significantly from 45 ± 1 to 20 ± 2 mmHg. When function fell to 50% of baseline, perfusion pressures ranged from 35 ± 0.5 to 2.5 ± 1 mmHg for flow reductions ranging from 50 to 100%. Identical contractile function at widely differing coronary perfusion pressures is incompatible with the vascular collapse theory.

scholarly journals Moderate Prenatal Alcohol Exposure Alters Functional Connectivity in the Adult Rat Brain

2016 ◽  
Vol 40 (10) ◽  
pp. 2134-2146 ◽  
Author(s):  
Carlos I. Rodriguez ◽  
Suzy Davies ◽  
Vince Calhoun ◽  
Daniel D. Savage ◽  
Derek A. Hamilton
Keyword(s):  
Functional Connectivity ◽  
Rat Brain ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Adult Rat ◽  
Adult Rat Brain ◽  
Prenatal Alcohol

scholarly journals Effects of early-life adversity on immune function are mediated by prenatal environment: Role of prenatal alcohol exposure

2017 ◽  
Vol 66 ◽  
pp. 210-220 ◽  
Author(s):  
Charlis Raineki ◽  
Tamara S. Bodnar ◽  
Parker J. Holman ◽  
Samantha L. Baglot ◽  
Ni Lan ◽  
...  
Keyword(s):  
Immune Function ◽  
Early Life ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Early Life Adversity ◽  
Prenatal Environment ◽  
Prenatal Alcohol

Prenatal Alcohol Exposure and Child Aggressive Behavior: The Moderating Role of Biological and Social Factors

2002 ◽  
Author(s):  
Chie Yumoto ◽  
Raluca Corobana ◽  
Lisa Chiodo ◽  
Robert J. Sokol ◽  
Sandra W. Jacobson ◽  
...  
Keyword(s):  
Aggressive Behavior ◽  
Social Factors ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Prenatal Alcohol ◽  
Moderating Role

scholarly journals Prenatal Alcohol Exposure Alters Steady-State and Activated Gene Expression in the Adult Rat Brain

2015 ◽  
Vol 39 (2) ◽  
pp. 251-261 ◽  
Author(s):  
Alexandre A. Lussier ◽  
Katarzyna A. Stepien ◽  
Sarah M. Neumann ◽  
Paul Pavlidis ◽  
Michael S. Kobor ◽  
...  
Keyword(s):  
Gene Expression ◽  
Steady State ◽  
Rat Brain ◽  
Prenatal Alcohol Exposure ◽  
Alcohol Exposure ◽  
Adult Rat ◽  
Adult Rat Brain ◽  
Prenatal Alcohol
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