Double-blind randomized phase II results comparing concurrent high-dose cisplatin chemorradiation (CRT) plus debio 1143 or placebo in high-risk patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN): A GORTEC study

Annals of Oncology ◽

10.1093/annonc/mdz394.062 ◽

2019 ◽

Vol 30 ◽

pp. v902 ◽

Cited By ~ 2

Author(s):

J. Bourhis ◽

X. Sun ◽

Y. Pointreau ◽

C. Sire ◽

C. Le Tourneau ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

High Risk ◽

Cell Carcinoma ◽

Head And Neck ◽

Locally Advanced ◽

High Dose ◽

Advanced Squamous Cell Carcinoma ◽

Double Blind ◽

Randomized Phase Ii ◽

Risk Patients

Download Full-text

LBA39 3-years follow-up of double-blind randomized phase II comparing concurrent high-dose cisplatin chemo-radiation plus xevinapant or placebo in high-risk patients with locally advanced squamous cell carcinoma of the head and neck

Annals of Oncology ◽

10.1016/j.annonc.2020.08.2269 ◽

2020 ◽

Vol 31 ◽

pp. S1168

Author(s):

J. Bourhis ◽

X. Sun ◽

C. Le Tourneau ◽

Y. Pointreau ◽

C. Sire ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

High Risk ◽

Cell Carcinoma ◽

Locally Advanced ◽

High Dose ◽

Advanced Squamous Cell Carcinoma ◽

Double Blind ◽

Randomized Phase Ii ◽

Risk Patients

Download Full-text

Debio 1143 and high-dose cisplatin chemoradiotherapy in high-risk locoregionally advanced squamous cell carcinoma of the head and neck: a double-blind, multicentre, randomised, phase 2 study

The Lancet Oncology ◽

10.1016/s1470-2045(20)30327-2 ◽

2020 ◽

Vol 21 (9) ◽

pp. 1173-1187 ◽

Cited By ~ 6

Author(s):

Xu-Shan Sun ◽

Yungan Tao ◽

Christophe Le Tourneau ◽

Yoann Pointreau ◽

Christian Sire ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

High Risk ◽

Cell Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

High Dose ◽

Advanced Squamous Cell Carcinoma ◽

Phase 2 ◽

Double Blind ◽

Phase 2 Study

Download Full-text

Faculty Opinions recommendation of Debio 1143 and high-dose cisplatin chemoradiotherapy in high-risk locoregionally advanced squamous cell carcinoma of the head and neck: a double-blind, multicentre, randomised, phase 2 study.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.738449325.793581438 ◽

2020 ◽

Author(s):

Sandra Nuyts ◽

Heleen Bollen

Keyword(s):

Squamous Cell Carcinoma ◽

High Risk ◽

Cell Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

High Dose ◽

Advanced Squamous Cell Carcinoma ◽

Phase 2 ◽

Double Blind ◽

Phase 2 Study

Download Full-text

Debio 1143 Combined with Concurrent High-Dose Cisplatin Chemoradiotherapy in Patients with High-Risk Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck: A Double Blind, Randomised, Placebo Controlled, Multicentre Phase 2 Study (GORTEC 2015-03)

SSRN Electronic Journal ◽

10.2139/ssrn.3552860 ◽

2020 ◽

Author(s):

Xu-Shan Sun ◽

Yungan Tao ◽

Christophe Le Tourneau ◽

Yoann Pointreau ◽

Christian Sire ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

High Risk ◽

Cell Carcinoma ◽

Head And Neck ◽

High Dose ◽

Advanced Squamous Cell Carcinoma ◽

Phase 2 ◽

Double Blind ◽

Multicentre Phase ◽

Phase 2 Study

Download Full-text

Phase II study of weekly high-dose cisplatin for six cycles in patients with locally advanced squamous cell carcinoma of the head and neck

European Journal of Cancer ◽

10.1016/s0959-8049(96)00311-5 ◽

1997 ◽

Vol 33 (1) ◽

pp. 61-65 ◽

Cited By ~ 19

Author(s):

A.S.T. Planting ◽

P.H.M. de Mulder ◽

A. de Graeff ◽

J. Verweij

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Head And Neck ◽

Phase Ii ◽

Squamous Cell ◽

Phase Ii Study ◽

Locally Advanced ◽

High Dose ◽

Advanced Squamous Cell Carcinoma

Download Full-text

Randomized Phase II/III Trial of Post-operative Chemoradiotherapy Comparing 3-Weekly Cisplatin with Weekly Cisplatin in High-risk Patients with Squamous Cell Carcinoma of Head and Neck: Japan Clinical Oncology Group Study (JCOG1008)

Japanese Journal of Clinical Oncology ◽

10.1093/jjco/hyu067 ◽

2014 ◽

Vol 44 (8) ◽

pp. 770-774 ◽

Cited By ~ 22

Author(s):

F. Kunieda ◽

N. Kiyota ◽

M. Tahara ◽

T. Kodaira ◽

R. Hayashi ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

High Risk ◽

Cell Carcinoma ◽

Head And Neck ◽

Oncology Group ◽

Japan Clinical Oncology Group ◽

Oncology Group Study ◽

Randomized Phase Ii ◽

Risk Patients ◽

Weekly Cisplatin

Download Full-text

Avelumab plus standard-of-care chemoradiotherapy versus chemoradiotherapy alone in patients with locally advanced squamous cell carcinoma of the head and neck: a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial

The Lancet Oncology ◽

10.1016/s1470-2045(20)30737-3 ◽

2021 ◽

Vol 22 (4) ◽

pp. 450-462

Author(s):

Nancy Y Lee ◽

Robert L Ferris ◽

Amanda Psyrri ◽

Robert I Haddad ◽

Makoto Tahara ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Head And Neck ◽

Locally Advanced ◽

Standard Of Care ◽

Advanced Squamous Cell Carcinoma ◽

Phase 3 ◽

Double Blind ◽

Double Blind Placebo ◽

Multicentre Phase

Download Full-text

Dose escalation study of Olaparib in addition to cisplatin based concurrent chemoradiotherapy for patients with high risk locally advanced squamous cell carcinoma of the head and neck (HNSCC)

http://isrctn.org/> ◽

10.1186/isrctn62346992 ◽

2013 ◽

Author(s):

Dymphna Lee

Keyword(s):

Squamous Cell Carcinoma ◽

High Risk ◽

Cell Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

Dose Escalation ◽

Concurrent Chemoradiotherapy ◽

Locally Advanced ◽

Advanced Squamous Cell Carcinoma ◽

Dose Escalation Study

Download Full-text

Abstract B268: A Phase I Study of CUDC-101, a multitarget inhibitor of HDACs, EGFR, and HER2, in combination with chemoradiation in patients with intermediate/high risk locally advanced squamous cell carcinoma of the head and neck.

10.1158/1535-7163.targ-13-b268 ◽

2013 ◽

Cited By ~ 1

Author(s):

Antonio Jimeno ◽

Thomas Galloway ◽

Lori Wirth ◽

Jill Gilbert ◽

Nabil Saba ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

High Risk ◽

Phase I ◽

Cell Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

Phase I Study ◽

Locally Advanced ◽

Advanced Squamous Cell Carcinoma

Download Full-text

Effects of aprepitant use in patients (pts) with locally advanced squamous cell carcinoma of the head and neck (LA SCCHN) treated with high-dose cisplatin and radiation (RT).

Journal of Clinical Oncology ◽

10.1200/jco.2010.28.15_suppl.5593 ◽

2010 ◽

Vol 28 (15_suppl) ◽

pp. 5593-5593

Author(s):

M. Ong ◽

J. Martin ◽

L. Sax ◽

D. S. Ernst ◽

E. Winquist

Keyword(s):

Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

Locally Advanced ◽

High Dose ◽

Advanced Squamous Cell Carcinoma

Download Full-text