scholarly journals A-200 Which Domains of Neuropsychological Functioning are Most Strongly Related to Impairment in Instrumental Activities of Daily Living?

2020 ◽  
Vol 35 (6) ◽  
pp. 995-995
Author(s):  
Clark H ◽  
Schroeder R ◽  
Martin P

Abstract Objective The current study investigated relationships between neuropsychological test findings and instrumental activities of daily living (IADLs) in a mixed sample of Mild and Major Neurocognitive Disorder (NCD). Method Archival data from a memory disorder clinic were analyzed. Patients (n = 68, mean age = 72.3, mean education = 13.2 years, 26.5% Mild NCD, 73.5% Major NCD) minimally completed the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) and the Delis-Kaplan Executive Function System (D-KEFS). Information on IADLs was obtained from family members via the Functional Activities Questionnaire (FAQ). Spearman correlations were calculated between individual IADLs from the FAQ, total FAQ ratings, RBANS index scores, and a composite executive functioning score (average scaled score on DKEFS Trail Making, Verbal Fluency, and Tower). Results Executive functioning was the only cognitive domain that significantly correlated (p < .05) with total FAQ ratings. However, all cognitive domains except language significantly correlated with individual IADLs. Tracking current events correlated with immediate memory, while financial management correlated with delayed memory. Attending to, understanding, and discussing TV, books, and magazines correlated with executive functioning and immediate and delayed memory. Remembering events correlated with attention and executive functioning. Shopping alone correlated with immediate memory, attention, and executive functioning, while operating basic kitchen appliances correlated with visuospatial skills, attention, and executive functioning. Traveling also correlated with visuospatial skills and executive functioning. Conclusions Executive functioning was the only domain associated with overall daily functioning; however, all domains except language corresponded with individual IADLs. Current findings highlight the utility of neuropsychological test findings in understanding the nuances of deficits in daily functioning.

2020 ◽  
Vol 35 (6) ◽  
pp. 813-813
Author(s):  
Roberts C ◽  
King J

Abstract Objective Informant reports of daily functioning are often useful when assessing functional skill impairments in neuropsychological dementia evaluations, given potential biases with self-reporting from low insight and/or a reluctance to endorse reduced independence. Two measures of informant functional skill assessments were compared within patients relative to their objective neurocognitive performances. Method Participants included 19 (32% male, 68% female; 21% Hispanic, 69% Caucasian) outpatient older adult dementia evaluations aged 60 to 90 years (Mean age = 74, SD = 7.7) who were accompanied by a family member or caregiver informant. The Activities of Daily Living Questionnaire (ADLQ) and the Lawton Activities of Daily Living and Instrumental Activities of Daily Living Scale (ADL/IADL) informant reports were compared relative to performances on the Hopkins Verbal Learning Test delayed recall trial (HVLT), Trail Making Test Part B (TMTB), CLOX: An Executive Clock Drawing Task (CLOX1), and the Controlled Oral Word Association Test, FAS and Animals (COWAT). Results Simple linear regression analyses indicated the ADLQ significantly predicted both TMTB (β = −.52, 95% CI [−.81, −.23], p < .01; R2 = .47) and HVLT (β = −.38, 95% CI [−.67, −.08], p < .01; R2 = .31) performances. The ADL/IADL scale significantly predicted TMTB performances (β = −.70, 95% CI [−1.1, −.30], p < .01; R2 = .46). A significant correlation was observed between ADLQ and ADL/IADL informant reports (r(17) = .60, p < .01). Conclusion There was a significant linear relationship between both ADLQ and ADL/IADL informant reports with TMTB performances. The ADLQ reports also significantly predicted HVLT performances. No significant relationships were observed between either ADLQ and ADL/IADL reports, and participants’ CLOX1 or COWAT FAS/Animals performances.


2021 ◽  
Vol 7 (3) ◽  
pp. 205521732110380
Author(s):  
Maureen van Dam ◽  
Sietske AM Sikkes ◽  
Emma Rammeloo ◽  
Evy Reinders ◽  
Julia R Jelgerhuis ◽  
...  

Neuropsychological test scores in people with MS (PwMS) do not fully reflect cognitive functioning in daily life. Therefore, we developed a questionnaire based on instrumental activities of daily living (IADL), using the Amsterdam IADL-Q© for Alzheimer’s disease as starting point. Forty-eight items were evaluated on relevance and clarity by (inter)national experts (n = 30), PwMS (n = 61) and proxies (n = 30). Consequently, four items were omitted, two items were merged and seven items were added. Fifty items were included in the IADL questionnaire specific to cognitive functioning in MS (the MS-IADL-Q). Future studies are warranted to assess the psychometric properties of the MS-IADL-Q.


2015 ◽  
Vol 21 (9) ◽  
pp. 688-698 ◽  
Author(s):  
Karen M. Lau ◽  
Mili Parikh ◽  
Danielle J. Harvey ◽  
Chun-Jung Huang ◽  
Sarah Tomaszewski Farias

AbstractOlder adults with early forms of neurodegenerative disease are at risk for functional disability, which is often defined by the loss of independence in instrumental activities of daily living (IADLs). The current study investigated the influence of mild changes in everyday functional abilities (referred to as functional limitations) on risk for development of incident functional disability. A total of 407 participants, who were considered cognitively normal or diagnosed with mild cognitive impairment (MCI) at baseline, were followed longitudinally over an average 4.1 years (range=0.8–9.2 years). Informant-based ratings from the Everyday Cognition (ECog; Farias et al., 2008) and the Instrumental Activities of Daily Living (Lawton & Brody, 1969) scales assessed the degree of functional limitations and incident IADL disability, respectively. Cox proportional hazards models revealed that more severe functional limitations (as measured by the Total ECog score) at baseline were associated with approximately a four-fold increased risk of developing IADL disability a few years later. Among the ECog domains, functional limitations in Everyday Planning, Everyday Memory, and Everyday Visuospatial domains were associated with the greatest risk of incident functional disability. These results remained robust even after controlling for participants’ neuropsychological functioning on tests of executive functions and episodic memory. Current findings indicate that early functional limitations have prognostic value in identifying older adults at risk for developing functional disability. Findings highlight the importance of developing interventions to support everyday abilities related to memory, executive function, and visuospatial skills in an effort to delay loss of independence in IADLs. (JINS, 2015,21, 688–698)


2019 ◽  
Vol 27 (4) ◽  
pp. 326-333 ◽  
Author(s):  
Christopher M. Nguyen ◽  
Christopher T. Copeland ◽  
Deborah A. Lowe ◽  
Daniel J. Heyanka ◽  
John F. Linck

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