scholarly journals Global gene expression profiling of somatic motor neuron populations with different vulnerability identify molecules and pathways of degeneration and protection

Brain ◽  
2010 ◽  
Vol 133 (8) ◽  
pp. 2313-2330 ◽  
Author(s):  
Eva Hedlund ◽  
Martin Karlsson ◽  
Teresia Osborn ◽  
Wesley Ludwig ◽  
Ole Isacson
Keyword(s):  
Gene Expression ◽  
Motor Neuron ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Global Gene Expression ◽  
Neuron Populations ◽  
Global Gene Expression Profiling

Global gene expression profiling of porcine endometria on Days 12 and 16 of the estrous cycle and pregnancy

2014 ◽  
Vol 82 (6) ◽  
pp. 897-909 ◽  
Author(s):  
Jolanta Kiewisz ◽  
Kamil Krawczynski ◽  
Pawel Lisowski ◽  
Agnieszka Blitek ◽  
Lech Zwierzchowski ◽  
...  
Keyword(s):  
Gene Expression ◽  
Gene Expression Profiling ◽  
Estrous Cycle ◽  
Expression Profiling ◽  
Global Gene Expression ◽  
Global Gene Expression Profiling

scholarly journals GLOBAL GENE EXPRESSION PROFILING OF SINGLE, CLONED BOVINE EMBRYOS WITH DIFFERENT DEVELOPMENTAL COMPETENCIES: THE GOOD, THE BAD, AND THE UGLY

2007 ◽  
Vol 77 (Suppl_1) ◽  
pp. 217-217
Author(s):  
Sadie Smith ◽  
Daniel Le Bourhis ◽  
Xavier Vignon ◽  
Yvan Heyman ◽  
Harris Lewin ◽  
...  
Keyword(s):  
Gene Expression ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Global Gene Expression ◽  
Bovine Embryos ◽  
Global Gene Expression Profiling ◽  
Cloned Bovine

scholarly journals Global Gene Expression Profiling of Circulating Tumor Cells

2005 ◽  
Vol 65 (12) ◽  
pp. 4993-4997 ◽  
Author(s):  
Denis A. Smirnov ◽  
Daniel R. Zweitzig ◽  
Bradley W. Foulk ◽  
M. Craig Miller ◽  
Gerald V. Doyle ◽  
...  
Keyword(s):  
Gene Expression ◽  
Gene Expression Profiling ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Expression Profiling ◽  
Global Gene Expression ◽  
Global Gene Expression Profiling

Global gene expression profiling in early-stage polycystic kidney disease in the Han:SPRD Cy rat identifies a role for RXR signaling

2011 ◽  
Vol 300 (1) ◽  
pp. F177-F188 ◽  
Author(s):  
Masanori Kugita ◽  
Kazuhiro Nishii ◽  
Miwa Morita ◽  
Daisuke Yoshihara ◽  
Hiroe Kowa-Sugiyama ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cell Proliferation ◽  
Kidney Disease ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Early Stage ◽  
Global Gene Expression ◽  
Rt Pcr ◽  
Polycystic Kidney ◽  
Global Gene Expression Profiling

Han:SPRD Cy is a spontaneous rat model of polycystic kidney disease (PKD) caused by a missense mutation in Pkdr1. Cystogenesis in this model is not clearly understood. In the current study, we performed global gene expression profiling in early-stage PKD cyst development in Cy/Cy kidneys and normal (+/+) kidneys at 3 and 7 days of postnatal age. Expression profiles were determined by microarray analysis, followed by validation with real-time RT-PCR. Genes were selected with over 1.5-fold expression changes compared with age-matched +/+ kidneys for canonical pathway analysis. We found nine pathways in common between 3- and 7-day Cy/Cy kidneys. Three significantly changed pathways were designated “Vitamin D Receptor (VDR)/Retinoid X Receptor (RXR) Activation,” “LPS/IL-1-Mediated Inhibition of RXR Function,” and “Liver X Receptor (LXR)/RXR Activation.” These results suggest that RXR-mediated signaling is significantly altered in developing kidneys with mutated Pkdr1. In gene ontology analysis, the functions of these RXR-related genes were found to be involved in regulating cell proliferation and organ morphogenesis. With real-time RT-PCR analysis, the upregulation of Ptx2, Alox15b, OSP, and PCNA, major markers of cell proliferation associated with the RXR pathway, were confirmed in 3- and 7-day Cy/Cy kidneys compared with 3-day +/+ kidneys. The increased RXR protein was observed in both the nucleus and cytoplasm of cystic epithelial cells in early-stage Cy/Cy kidneys, and the RXR-positive cells were strongly positive for PCNA staining. Taken together, cell proliferation and organ morphogenesis signals transduced by RXR-mediated pathways may have important roles for cystogenesis in early-stage PKD in this Pkdr1-mutated Cy rat.

Global Gene Expression Profiling in Cultured Cells Is Strongly Influenced by Treatment with siRNA–Cationic Liposome Complexes

2008 ◽  
Vol 25 (11) ◽  
pp. 2497-2504 ◽  
Author(s):  
Tatsuaki Tagami ◽  
Kiyomi Hirose ◽  
Jose Mario Barichello ◽  
Tatsuhiro Ishida ◽  
Hiroshi Kiwada
Keyword(s):  
Gene Expression ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Cultured Cells ◽  
Cationic Liposome ◽  
Global Gene Expression ◽  
Global Gene Expression Profiling

Global Gene Expression Profiling in Larval Zebrafish Exposed to Microcystin-LR and Microcystis Reveals Endocrine Disrupting Effects of Cyanobacteria

2011 ◽  
Vol 45 (5) ◽  
pp. 1962-1969 ◽  
Author(s):  
Emily D. Rogers ◽  
Theodore B. Henry ◽  
Michael J. Twiner ◽  
Julia S. Gouffon ◽  
Jackson T. McPherson ◽  
...  
Keyword(s):  
Gene Expression ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Global Gene Expression ◽  
Larval Zebrafish ◽  
Endocrine Disrupting ◽  
Global Gene Expression Profiling

Global gene expression profiling reveals a key role of CD44 in hepatic oval-cell reaction after 2-AAF/CCl4 injury in rodents

2009 ◽  
Vol 132 (5) ◽  
pp. 479-489 ◽  
Author(s):  
Chien-Chang Chiu ◽  
Jin-Chuan Sheu ◽  
Chien-Hung Chen ◽  
Cha-Ze Lee ◽  
Ling-Ling Chiou ◽  
...  
Keyword(s):  
Gene Expression ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Global Gene Expression ◽  
Oval Cell ◽  
Cell Reaction ◽  
Global Gene Expression Profiling ◽  
Hepatic Oval Cell
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