scholarly journals Gene expression profile in a glioma cell line resistant to cell death induced by a the chimeric tumor suppressor-1 (CTS-1), a dominant-positive variant of p53—the role of NFκB

2009 ◽  
Vol 31 (3) ◽  
pp. 411-418 ◽  
Author(s):  
Janina Seznec ◽  
Simone Weit ◽  
Ulrike Naumann
Keyword(s):  
Gene Expression ◽  
Cell Death ◽  
Tumor Suppressor ◽  
Cell Line ◽  
Gene Expression Profile ◽  
Expression Profile ◽  
Glioma Cell ◽  
Glioma Cell Line

Cell death gene expression profile: Role of RIPK2 in dengue virus-mediated apoptosis

2011 ◽  
Vol 156 (1-2) ◽  
pp. 25-34 ◽  
Author(s):  
Atthapan Morchang ◽  
Umpa Yasamut ◽  
Janjuree Netsawang ◽  
Sansanee Noisakran ◽  
Wiyada Wongwiwat ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cell Death ◽  
Dengue Virus ◽  
Gene Expression Profile ◽  
Expression Profile ◽  
Cell Death Gene

scholarly journals P01.17 * ROLE OF PHOSPHATYDILCHOLINE-SPECIFIC PHOSPHOLIPASE C IN MODULATION OF CXCL12/CXCR4 AXIS IN A HUMAN GLIOMA CELL LINE

2014 ◽  
Vol 16 (suppl 2) ◽  
pp. ii30-ii30 ◽  
Author(s):  
L. Mercurio ◽  
A. Ricci ◽  
S. Cecchetti ◽  
A. Pacella ◽  
F. Podo ◽  
...  
Keyword(s):  
Phospholipase C ◽  
Cell Line ◽  
Glioma Cell ◽  
Glioma Cell Line ◽  
Human Glioma ◽  
Human Glioma Cell Line ◽  
Human Glioma Cell ◽  
Cxcr4 Axis

scholarly journals MIF inhibition reverts the gene expression profile of human melanoma cell line-induced MDSCs to normal monocytes

Genomics Data ◽  
2016 ◽  
Vol 7 ◽  
pp. 240-242 ◽  
Author(s):  
Sabine Waigel ◽  
Beatriz E. Rendon ◽  
Gwyneth Lamont ◽  
Jamaal Richie ◽  
Robert A. Mitchell ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cell Line ◽  
Gene Expression Profile ◽  
Expression Profile ◽  
Melanoma Cell ◽  
Melanoma Cell Line ◽  
Human Melanoma ◽  
Human Melanoma Cell Line ◽  
Human Melanoma Cell

The role of ecto-5′-nucleotidase/CD73 in glioma cell line proliferation

2008 ◽  
Vol 319 (1-2) ◽  
pp. 61-68 ◽  
Author(s):  
Luci Bavaresco ◽  
Andressa Bernardi ◽  
Elizandra Braganhol ◽  
Angélica Regina Cappellari ◽  
Liliana Rockenbach ◽  
...  
Keyword(s):  
Cell Line ◽  
Glioma Cell ◽  
Glioma Cell Line

scholarly journals The role of Alk-1 and Alk-5 in the mechanosensing of chondrocytes

2014 ◽  
Vol 19 (4) ◽  
Author(s):  
Patricia Sanz-Ramos ◽  
Javier Dotor ◽  
Iñigo Izal-Azcárate
Keyword(s):  
Gene Expression ◽  
Mouse Model ◽  
Gene Expression Profile ◽  
Expression Profile ◽  
Peptide Inhibitors ◽  
Mechanical Environment ◽  
Chondrocyte Phenotype ◽  
Cartilage Cells ◽  
Alk 5

AbstractWe aim to demonstrate the role of Alk receptors in the response of hydrogel expansion. Chondrocytes from rat knees were cultured onto plastic and hydrogel surfaces. Alk-1 and Alk-5 were overexpressed or silenced and the effects on cells during expansion were tested and confirmed using peptide inhibitors for TGFβ. Overexpression of Alk-5 and silencing of Alk-1 led to a loss of the chondrocyte phenotype, proving that they are key regulators of chondrocyte mechanosensing. An analysis of the gene expression profile during the expansion of these modified cartilage cells in plastic showed a better maintenance of the chondrocyte phenotype, at least during the first passages. These passages were also assayed in a mouse model of intramuscular chondrogenesis. Our findings indicate that these two receptors are important mediators in the response of chondrocytes to changes in the mechanical environment, making them suitable targets for modulating chondrogenesis. Inhibition of TGFβ could also be effective in improving chondrocyte activity in aged or expanded cells that overexpress Alk-1.

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