scholarly journals Effects of vitamin B6 on the growth performance, intestinal morphology, and gene expression in weaned piglets that are fed a low-protein diet1

2020 ◽  
Vol 98 (2) ◽  
Author(s):  
Lanmei Yin ◽  
Jun Li ◽  
Huiru Wang ◽  
Zhenfeng Yi ◽  
Lei Wang ◽  
...  
Keyword(s):  
Growth Performance ◽  
Mrna Expression ◽  
Inflammatory Cytokines ◽  
Vitamin B6 ◽  
Animal Health ◽  
Dietary Supplementation ◽  
Experimental Period ◽  
Intestinal Morphology ◽  
Weaned Piglets ◽  
Cox 2

Abstract Vitamin B6 (VB6), which is an essential functional substance for biosome, plays an irreplaceable role in animal health. However, there are few studies that focus on the correlation between VB6 and intestinal health in weaned piglets. This study was conducted to investigate the effects of VB6 on the growth performance, intestinal morphology, and inflammatory cytokines and amino acid (AA) transporters mRNA expression in weaned piglets that are fed a low crude-protein (CP, 18%) diet. Eighteen crossbred piglets with initial body weights of 7.03 ± 0.17 kg (means ± SEM), weaned at 21-d age, were randomly assigned three diets with 0, 4, and 7 mg/kg VB6 supplementation, respectively. The experimental period lasted 14 days. Our results showed that there were no significant differences in growth performance, diarrhea rate, and biochemical parameters among the three treatments. In the jejunum, dietary VB6 supplementation did not affect the morphology and positive Ki67 counts. Dietary supplementation with 4 mg/kg VB6 decreased the mRNA expression of COX-2, IL-10, and TGF-β (P < 0.05). Dietary supplementation with 7 mg/kg VB6 increased the mRNA expression of SLC7A1, SLC7A6, SLC16A14, and SLC38A5 (P < 0.05) and 4 or 7 mg/kg VB6 decreased SLC36A1 mRNA expression (P < 0.05). In the ileum, VB6 supplementation did not affect positive Ki67 counts but significantly decreased villus area (P < 0.05) and tended to decrease villus height (P = 0.093). Dietary supplementation with 4 mg/kg VB6 had significantly increased the mRNA expression of IL-1β, TNF-α, COX-2, IL-10, and TGF-β (P < 0.05). Dietary supplementation with 4 or 7 mg/kg VB6 had significantly decreased SLC6A20, SLC7A1, SLC7A6, SLC16A14, and SLC38A5 mRNA expression (P < 0.05). These findings suggest that dietary supplementation of VB6 mainly down-regulated inflammatory cytokines and up-regulated AA transporters mRNA expression in jejunum, while up-regulated (4 mg/kg) inflammatory cytokines and down-regulated AA transporters mRNA expression in ileum, which may provide a reference for the intestinal development of weaned piglets that are fed a low-CP diet.

scholarly journals PSVI-40 Effects of dietary glucan on intestinal morphology, immunity response, barrier function and antioxidant capacity in weaning pigs

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 212-213
Author(s):  
xia xiong ◽  
Lvliang Wu ◽  
Yirui Shao ◽  
Jian zou ◽  
Yulong Yin
Keyword(s):  
Antioxidant Capacity ◽  
Growth Performance ◽  
Mrna Expression ◽  
Dietary Supplementation ◽  
Basal Diet ◽  
Intestinal Morphology ◽  
Control Group ◽  
Gut Health ◽  
Weaned Piglets ◽  
Weaning Piglets

Abstract Glucan has been studied as a potential alternative to antibiotics for animals in recent years. The aim of this study was to evaluate the effect of dietary glucan on growth performance and gut health of weaning piglets, which is a water-soluble extracellular ꞵ-glucan produced by Agrobacterium sp. ZX09. A total of 108 weaned piglets (21 d of age; 6.05 ± 0.36 kg) were randomly assigned (6 pens/diet; 18 piglets/pen) to 3 dietary treatments consisting of a basal diet (control group) or the basal diet supplemented with 20 ppm olaquindox or 200 ppm glucan for 14 days, respectively. The results showed that piglets fed with glucan had greater (P < 0.05) body weight and average daily gain than piglets in control group. Piglets fed with glucan or antibiotic had greater villus height to crypt depth ratio on duodenum compared with control group (P < 0.05). The mRNA expression of Claudin-1 on duodenum or ileum was higher (P < 0.05) in glucan group than that on the other groups. The mRNA expression of TLR4, MYD88 and NFκB on jejunum were lower (P < 0.05) in glucan or antibiotic group than those in control group. Dietary supplementation with glucan tended to increase the IL-10 and SIgA concentration on ileum (0.05 < P < 0.1). Dietary supplementation with glucan tended to increase the total antioxidant capacity on jejunum (P = 0.093). In conclusion, 200 ppm glucan or 20 ppm olaquindox can improve the growth performance of weaning piglets. The glucan may can accelerate the growth of weaned piglets by improving gut health. This research will provide guidance for the olaquindox alternative on growing piglets.

scholarly journals Effects of vitamin B6 on growth, diarrhea rate, intestinal morphology, function, and inflammatory factors expression in a high-protein diet fed to weaned piglets1

2019 ◽  
Vol 97 (12) ◽  
pp. 4865-4874
Author(s):  
Jun Li ◽  
Lanmei Yin ◽  
Lei Wang ◽  
Jianzhong Li ◽  
Pengfei Huang ◽  
...  
Keyword(s):  
Amino Acid ◽  
Mrna Expression ◽  
Inflammatory Cytokines ◽  
Vitamin B6 ◽  
High Protein Diet ◽  
Intestinal Morphology ◽  
Protein Diet ◽  
Weaned Piglets ◽  
Villus Height ◽  
Crypt Depth

Abstract Vitamin B6 (VB6) is an important coenzyme factor which participates in many metabolic reactions, especially amino acid metabolism. There are few reports on how VB6 mediates weaned piglet intestinal health. This study purposed to investigate dietary VB6 effects on growth, diarrhea rates, and intestinal morphology and function in weaned piglets fed a high-crude protein (22% CP) diet. Eighteen 21-d-old weaned [(Yorkshire × Landrace) × Duroc] piglets with body weights of 7.03 ± 0.15 (means ± SEM) kg were randomly assigned into 3 VB6-containing dietary treatments. Vitamin B6 content was: 0, 4, and 7 mg/kg, respectively. The feeding period lasted 14 d. The results showed that no significant difference existed for the growth performance. The 7 mg/kg VB6 group had a tendency to decrease diarrhea rate (P = 0.065). Blood biochemical parameters analysis demonstrated that total protein, cholesterol, and high-density lipoprotein significantly increased in the 7 mg/kg VB6 group (P < 0.05). In the jejunum, no significant differences were detected for villus height, villus width, crypt depth, villus height and crypt depth ratios, and positive Ki67 counts and the mRNA expression of inflammatory cytokines. Vitamin B6 significantly increased the mRNA expression of SLC6A19 and SLC6A20 (P < 0.05) and decreased the mRNA expression of SLC36A1 (P < 0.05). In the ileum, VB6 significantly increased villus height and villus width (P < 0.05) while decreased positive Ki67 cell counts for 7 mg/kg VB6 group (P < 0.05). Vitamin B6 had significantly increased the mRNA expression of interleukin-1β, tumor necrosis factor-α,cyclo-oxygen-ase-2, and transforming growth factor-β (P < 0.05). Vitamin B6 also had significantly increased mRNA expression of SLC6A19, SLC7A6, SLC7A7, and SLC36A1 (P < 0.05). These findings suggest that dietary supplementation with VB6 may affect the intestinal morphology and absorption and metabolism of protein in weaned piglets fed a high-protein diet by altering the expression of intestinal inflammatory cytokines and amino acid transporters.

scholarly journals Effects of Dietary Zinc Sources on Growth Performance and Gut Health of Weaned Piglets

2021 ◽  
Vol 12 ◽  
Author(s):  
Hui Diao ◽  
Jiayou Yan ◽  
Shuwei Li ◽  
Shengyao Kuang ◽  
Xiaolan Wei ◽  
...  
Keyword(s):  
Growth Performance ◽  
Mrna Expression ◽  
Dietary Supplementation ◽  
Basal Diet ◽  
Expression Level ◽  
Control Group ◽  
Mrna Expression Level ◽  
Gut Health ◽  
Weaned Piglets ◽  
Zinc Sources

The present study aimed to investigate the effects of dietary zinc sources on the growth performance and gut health of weaned piglets. In total, 96 Duroc × Landrace × Yorkshire (DLY) weaned piglets with an initial average body weight of 8.81±0.42kg were divided into four groups, with six replicates per treatment and four pigs per replicate. The dietary treatment groups were as follows: (1) control group, basal diet; (2) zinc sulphate (ZnSO4) group, basal diet +100mg/kg ZnSO4; (3) glycine zinc (Gly-Zn) group, basal diet +100mg/kg Gly-Zn and (4) zinc lactate group, and basal diet +100mg/kg zinc lactate. The whole trial lasted for 28days. Decreased F/G was noted in the Gly-Zn and zinc lactate groups (p<0.05). The zinc lactate group had a lower diarrhea rate than the control group (p<0.05). Moreover, the ZnSO4, Gly-Zn, and zinc lactate groups had significantly higher apparent total tract digestibility of dry matter (DM), crude protein (CP), ether extract (EE), crude ash, and zinc than the control group (p<0.05). The Gly-Zn and zinc lactate groups had higher jejunal villus height and a higher villus height:crypt depth ratio than the control group (p<0.05). In addition, the ZnSO4, Gly-Zn and zinc lactate groups had a significantly lower mRNA expression level of jejunal ZRT/IRT-like protein 4 (ZIP4) and higher mRNA expression level of jejunal interleukin-1β (IL-1β) than the control group (p<0.05). The mRNA expression level of jejunal zinc transporter 2 (ZNT2) was higher and that of jejunal Bcl-2-associated X protein (Bax) was lower in the Gly-Zn and zinc lactate groups than in the control group (p<0.05). Moreover, the zinc lactate group had a higher count of Lactobacillus spp. in the cecal digesta and higher mRNA expression levels of jejunal occludin and mucin 2 (MUC2) than the control group (p<0.05). In conclusion, dietary supplementation with 100mg/kg ZnSO4, Gly-Zn, or zinc lactate could improve the growth performance and gut barrier function of weaned piglets. Dietary supplementation with organic zinc, particularly zinc lactate, had the best effect.

scholarly journals Effects of dietary supplementation with exogenous catalase on growth performance, oxidative stress, and hepatic apoptosis in weaned piglets challenged with lipopolysaccharide

2020 ◽  
Vol 98 (3) ◽  
Author(s):  
Yang Li ◽  
Xilun Zhao ◽  
Xuemei Jiang ◽  
Ling Chen ◽  
Liang Hong ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Growth Performance ◽  
Mrna Expression ◽  
Rectal Temperature ◽  
Caspase 3 ◽  
Dietary Supplementation ◽  
Basal Diet ◽  
Weaned Piglets ◽  
Post Challenge ◽  
Blood Samples

Abstract Two experiments were conducted to investigate the effects of exogenous catalase (CAT) in the diet of weaned piglets on growth performance, oxidative capacity, and hepatic apoptosis after challenge with lipopolysaccharide (LPS). In experiment 1, 72 weaned piglets [Duroc × Landrace × Yorkshire, 6.90 ± 0.01 kg body weight (BW), 21 d of age] were randomly assigned to be fed either a basal diet (CON group) or a basal diet supplemented with 2,000 mg/kg CAT (CAT group; dietary CAT activity, 120 U/kg) for 35 d. Blood samples were collected on day 21 and day 35. At the end of this experiment, 12 pigs were selected from each of the CON and CAT groups, and six pigs were injected with LPS (50 μg/kg BW), while the remaining six pigs were injected with an equal amount of sterile saline, resulting in a 2 × 2 factorial arrangement of treatments (experiment 2). Blood samples and rectal temperature data were collected 0 and 4 h after challenge, and liver samples were obtained after evisceration. The gain-to-feed ratio was higher (P < 0.05) in piglets in the CAT group than in those in the CON group from day 1 to 35. Catalase and total superoxide dismutase (T-SOD) activities were higher (P < 0.05), whereas malondialdehyde (MDA) concentrations were lower (P < 0.05), in piglets in the CAT group than in those in the CON group at day 35. During challenge, rectal temperature and liver MDA and H2O2 concentrations increased significantly (P < 0.05), whereas plasma CAT and glutathione peroxidase (GSH-Px) activities and liver CAT activity decreased markedly (P < 0.05), in LPS-challenged piglets 4 h post-challenge. Increased CAT activity and decreased MDA concentration were observed in the plasma and liver of piglets in the CAT group 4 h post-challenge (P < 0.05). Dietary CAT supplementation markedly suppressed the LPS-induced decrease in plasma GSH-Px activity and liver CAT activity to levels observed in the CON group (P < 0.05) as well as significantly decreasing the concentration and mRNA expression of caspase-3 and caspase-9 (P < 0.05). LPS-induced liver injury was also attenuated by dietary CAT supplementation, as demonstrated by a decrease in liver caspase-3 mRNA expression (P < 0.05). Overall, dietary supplementation with 2,000 mg/kg exogenous CAT (dietary CAT activity, 120 U/kg) improves growth performance and has a beneficial effect on antioxidant capacity in weaned piglets; alleviates oxidative stress and reduces liver damage by suppressing hepatic apoptosis in LPS-challenged piglets.

Dietary Supplementation of β-Carotene on Growth Performance, Jejunal Permeability and Tight Junction Proteins in Weaned piglets

2020 ◽  
Author(s):  
Wuying Lang ◽  
Haizhou Gong ◽  
Ruonan Li ◽  
Min Wu ◽  
Qianran Chu ◽  
...  
Keyword(s):  
Tight Junction ◽  
Growth Performance ◽  
Dietary Supplementation ◽  
Intestinal Morphology ◽  
Control Group ◽  
Tight Junction Proteins ◽  
Weaned Piglets ◽  
Zonula Occludens ◽  
Β Carotene ◽  
Junction Proteins

Abstract Background: Weaning causes stress syndrome in the newborns, while it can lead to many intestinal diseases. The aim of this study was to determine the dietary supplementation of β-carotene on growth performance, jejunal permeability and tight junction proteins in weaned piglets, and explore the underlying mechanisms by which β-carotene regulates tight junction proteins. The positive control group was fed sow's milk throughout the trial. The negative control group was weaned at d 21 without any supplementation. Two experimental groups of piglets were weaned at d 21 and fed 40 mg/kg or 80 mg/kg β-carotene-supplemented diets from d 14 to d 24, respectively. Blood and the jejunum were collected at d 24. Results: The results showed that β-carotene at 80 mg/kg increased initial and final body weight and average daily feed intake, improved the villus height at d 24 (p<0.05) but reduced crypt depth in weaned piglets at d 24 (p<0.05). Additionally, β-carotene protected intestinal morphology. Supplemental 80 mg/kg β-carotene reduced the concentrations of D-lactic acid and diamine oxidase in serum (p<0.05) but enhanced the mRNA expression of claudin-3, occludin (p<0.05), and zonula occludens protein-1(p>0.05) and the protein levels of claudin-3 (p<0.01), occludin (p<0.05), and zonula occludens protein-1 (p>0.05) in the jejunum at d 24. Using intestinal epithelial cells and a Rac1 inhibitor in vitro, we demonstrated that the β-carotene-induced higher tight junction proteins might depend on the Rac1 pathway. Conclusions: β-carotene improved growth performance and attenuated jejunal permeability and tight junction proteins in weaned piglets, suggesting that β-carotene at 80 mg/kg may be an effective way for keeping healthier intestine of weaning piglets due to weaning.

scholarly journals Effects of Dietary Supplementation of Lactobacillus delbrueckii on Gut Microbiome and Intestinal Morphology in Weaned Piglets

2021 ◽  
Vol 8 ◽  
Author(s):  
Xiao-Long Wang ◽  
Zhu-Ying Liu ◽  
Ying-Hui Li ◽  
Ling-Yuan Yang ◽  
Jie Yin ◽  
...  
Keyword(s):  
Growth Performance ◽  
Relative Abundance ◽  
Dietary Supplementation ◽  
Basal Diet ◽  
Isobutyric Acid ◽  
Intestinal Morphology ◽  
Lactobacillus Delbrueckii ◽  
Weaned Piglets ◽  
Experimental Time ◽  
And Performance

Lactobacillus delbrueckii is a Gram-positive bacterium mostly used in the dairy industry for yogurt and cheese. The present study was designed to evaluate the effects of Lactobacillus delbrueckii on serum biochemical parameters, intestinal morphology, and performance by supplementing at a dietary level of 0.1% in diets for weaned piglets. Eighty healthy weaned piglets (initial body weight: 7.56 ± 0.2 kg) were randomly divided into two feeding groups with four replicates in each group (n = 10 animals per replicate); piglets were fed with basal diet (CON) or basal diet containing 0.1% Lactobacillus delbrueckii (LAC). The results showed that dietary supplementation of Lactobacillus delbrueckii improved growth performance and increased serum HDL and insulin levels in piglets on the 28th day of the experimental time (p &lt; 0.05). The gut microbe analysis revealed that Lactobacillus delbrueckii significantly decreased the relative abundance of the phyla Bacteroidetes, but increased the relative abundance of the phyla Firmicutes. The Lactobacillus delbrueckii also significantly increased the relative abundance of Bifidobacterium and Lactobacillus at the genus level of the bacterial community in the ileum, but decreased the relative abundance of unclassified Clostridiales. Moreover, Lactobacillus delbrueckii improved mucosal morphology by obtaining higher intestinal villus height (p &lt; 0.05), significantly increasing the concentrations of butyrate, isobutyric acid, and isovaleric acid in colonic chyme of piglets, but decreasing the intestinal pH at the duodenum and ileum on the 28th day of the experimental time. In conclusion, dietary supplementation of Lactobacillus delbrueckii in the diet of weaned piglets can improve intestinal morphology and modulate the microbiota community to promote growth performance.

scholarly journals Dietary ZnO and arginine supplementation on the dynamic change of microbiota, intestinal morphology, and immune function of weaned pigs subjected to heat stress

2020 ◽  
Author(s):  
Se Young Yoon ◽  
SooJin Sa ◽  
Eun Seok Cho ◽  
HanSeo Ko ◽  
Ga Won Kim ◽  
...  
Keyword(s):  
Heat Stress ◽  
Growth Performance ◽  
Mrna Expression ◽  
Immune Status ◽  
Phase 1 ◽  
Dietary Supplementation ◽  
Intestinal Morphology ◽  
Weaned Pigs ◽  
Weaning Stress ◽  
Tnf Α

Abstract Background. Weaning stress is an economically important problem in the pigs, and the economic loss of the growth performance reduction is even more critical if the heat stress adds to the weaning stress. The supplementation of ZnO is an effective option in reducing the adverse effects of weaning time. This study aimed to investigate the effect of the L-arginine (Arg) inclusion and different doses of ZnO to determine the best dietary supplementation ratio on growth performance, intestinal microbiota and integrity, and immune status in weaned pigs. A total of 180 weaned pigs (28 day-old) were randomly allotted to six treatments with 6 replicate pens in each treatment and 5 pigs per pen. The dietary treatments were: control diet (Con; with 1.1% Arg and without ZnO supplementation); Con + 2500 ppm Zn as ZnO (P-Zn); Con + 1.6% Arg (ARG); Con + 500 ppm of Zn as ZnO + 1.6% Arg (ZnArg1); Con + 1000 ppm of Zn as ZnO + 1.6% Arg (ZnArg2); P-Zn + 1.6% Arg (ZnArg3). Results. The overall result showed that the inclusion of ZnArg3 significantly improved the average daily gain compared with the Con treatment. There was a reduction of feed intake in the Con diet compared with the ZnArg3 diet at phase 1 and overall. At phase 1, the weaned pigs in the ZnArg3 and P-Zn groups exhibited the decreased population of Clostridium spp. in the ileum compared with those of the Con group. In addition, a lower ileal Clostridium spp. population was detected in the ZnArg2 pigs compared with the Con pigs. At phase 2, the colonization of Clostridium spp. was higher in the Con and ARG treatments compared with ZnArg3 treatment. The weaned pigs fed the ZnArg1 and ZnArg3 diets showed a greater villus height of duodenum compared with the Con and P-Zn treatments. The count of eosinophil was significantly higher in the Con and ZnArg1 compared with the ZnArg2 and ZnArg3 treatments. The weaned pigs in the Con group showed increased mRNA expression of HSP27 in the liver compared with the P-Zn, ZnArg1, ZnArg2, and ZnArg3 groups. When fed the basal diet, weaned pigs exhibited enhanced mRNA expressions of IL-6 in the muscle compared with the ZnArg3 group. Dietary supplementation with ZnArg2 decreased the mRNA expressions of IFNγ in the muscle compared with the Con group. Supplementation with P-Zn, ZnArg1, ZnArg2, and ZnArg3 exhibited decreased mRNA expressions of TNF-α compared with the Con group. The mRNA gene expressions of IL-4 were decreased in the jejunum of P-Zn, ARG, ZnArg1, ZnArg2, and ZnArg3 weaned pigs compared with the Con group. The jejunum gene expression of TLR4 was upregulated in the Con and ARG treatments compared with the ZnArg1 and ZnArg3. The ZnArg1, ZnArg2, and ZnArg3 treatments showed a lower mRNA expression of TNF-α compared with the Con group. Conclusion. The Arg supplementation did not improve the growth performance, microbial composition, or immune status of weaned pigs but showed a similar growth performance when supplemented with 500 ppm Zn as ZnO compared with 2500 ppm Zn as ZnO.

scholarly journals Effects of Dietary Supplementation with Clostridium butyricum on Growth Performance, Serum Immunity, Intestinal Morphology, and Microbiota as an Antibiotic Alternative in Weaned Piglets

Animals ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. 2287
Author(s):  
Yunsheng Han ◽  
Chaohua Tang ◽  
Ying Li ◽  
Yanan Yu ◽  
Tengfei Zhan ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Growth Performance ◽  
Dietary Treatment ◽  
Basal Diet ◽  
Experimental Period ◽  
Serum Levels ◽  
Short Chain Fatty Acids ◽  
Intestinal Morphology ◽  
Weaned Piglets ◽  
Fecal Score

This study investigated the effects of Clostridium butyricum (C. butyricum) use on growth performance, serum immunity, intestinal morphology, and microbiota as an antibiotic alternative in weaned piglets. Over the course of 28 days, 120 piglets were allocated to four treatments with six replicates of five piglets each. The treatments were: CON (basal diet); AGP (basal diet supplemented with 0.075 g/kg chlortetracycline, 0.055 g/kg kitasamycin, and 0.01 g/kg virginiamycin); CBN (basal diet supplemented with normal dosage of 2.5 × 108 CFU/kg C. butyricum); and CBH (basal diet supplemented with high dosage of 2.5 × 109 CFU/kg C. butyricum). Body weight (BW) and feed consumption were recorded at the beginning and on days 14 and 28 of the experiment, and representative feed samples and fresh feces were collected from each pen between days 26 and 28. Average fecal score of diarrhea was visually assessed each morning during the experimental period. On the morning of days 14 and 28, blood samples were collected to prepare serum for immune and antioxidant parameters measurement. One male piglet close to the average group BW was selected from each replicate and was slaughtered on day 21 of the experiment. Intestinal crypt villi, and colonic microbiota and its metabolites short-chain fatty acids were measured. Compared to the CON group, the CBN and AGP groups significantly decreased (p < 0.05) the ratio of feed to weight gain by 8.86% and 8.37% between days 1 and 14, 3.96% and 13.36% between days 15 and 28, 5.47% and 11.44% between days 1 and 28. Dietary treatment with C. butyricum and AGPs significantly decreased the average fecal score during the experimental period (p < 0.05). The apparent total tract digestibility of dry matter, organic matter, and total carbohydrates in the CBH group were higher respectively at 3.27%, 2.90%, and 2.97%, than those in the CON or AGP groups (p < 0.05). Compared to the CON group, the CBH group significantly increased short-chain fatty acids in colon and villus height in the jejunum (p < 0.05). The CBN group had higher serum levels of immunoglobulins, interleukin 2 (IL-2), and glutathione peroxidase (GSH-PX) activity, but lower serum levels of IL-1β and IL-6, and a lower aspartate aminotransferase (AST), alkaline phosphatase (ALP), and gamma-glutamyl transpeptidase (γ-GT) activity (p < 0.05), while compared to the CON group. Dietary treatment with C. butyricum significantly increased the relative abundance of Streptococcus and Bifidobacterium (p < 0.05). In summary, diet with C. butyricum increased the growth performance and benefited the health of weaned piglets.

Dietary supplementation with Bacillus subtilis and xylo-oligosaccharides improves growth performance and intestinal morphology and alters intestinal microbiota and metabolites in weaned piglets

2021 ◽  
Author(s):  
Hao Ding ◽  
Xichen Zhao ◽  
Md. Abul Kalam Azad ◽  
C Ma ◽  
QK Gao ◽  
...  
Keyword(s):  
Bacillus Subtilis ◽  
Microbial Community ◽  
Growth Performance ◽  
Intestinal Microbiota ◽  
Dietary Supplementation ◽  
Intestinal Morphology ◽  
Weaned Piglets ◽  
Intestinal Microbial Community

The present study was conducted to investigate the effects of dietary supplementation with Bacillus subtilis (BS) and xylo-oligosaccharides (XOS) on growth performance, intestinal morphology, intestinal microbial community, and metabolites of...

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