scholarly journals The Neurobiology of Resilience

Author(s):  
Adriana Feder ◽  
Sarah R. Horn ◽  
Margaret Haglund ◽  
Steven M. Southwick ◽  
Dennis S. Charney

Resilience is the ability to adapt successfully in the face of severe stress, trauma, or adversity. Over the past several decades, a wide range of studies in children and later in adults identified several key psychosocial characteristics associated with resilience, including emotion regulation, cognitive flexibility, positive emotions, and the availability of social support, among others. More recent studies are increasingly employing integrative approaches, incorporating genomic, neuroendocrine, and neuroimaging data to the study of resilience. This chapter reviews our current understanding of the neurobiology of resilience from genomic, developmental, psychosocial, neuroendocrine, brain circuitry, and integrative perspectives, and includes a final section focusing on implications for prevention and treatment of stress-related psychopathology.

2018 ◽  
Vol 10 (12) ◽  
pp. 4337 ◽  
Author(s):  
Heitor Teixeira ◽  
Leonardo van den Berg ◽  
Irene Cardoso ◽  
Ardjan Vermue ◽  
Felix Bianchi ◽  
...  

Agroecology is increasingly promoted by scientists, non-governmental organisations (NGO’s), international organisations and peasant movements as an approach to foster the transition to sustainable and equitable food systems. The challenges to agroecological transitions are not the same for all farmers, as they can face different social and bio-physical conditions. We developed a farm typology combining participatory and quantitative methodologies to assess and categorise farm diversity and its implications for developing strategies to promote agroecological transitions. The participatory typology was developed during workshops to acquire insights on local farmers’ perceptions and knowledge, and to generate hypotheses on family farm diversity. The participatory-based hypotheses were tested in the quantitative farm characterisation, which provided information on household characteristics, production strategies, land use, participation in public policies and extension services. Farms were located in Zona da Mata, Minas Gerais, Brazil, which harbour a wide diversity of farmers and where different actors have been engaged in agroecological transitions for the past 30 years. Our main findings were: (i) In the face of agroecological transitions, farmers differ in their management strategies, practices and principles; (ii) farmers identified as agroecological typically had stronger engagements in a network composed of farmers’ organisations, universities and NGO’s; (iii) agroecological farms showed great potential to provide a wide range of ecosystem services as they featured a higher crop diversity and a higher number of crops for self-consumption; (iv) to promote agroecology, it is crucial to recognise peasant knowledge, to change the dominant discourse on agriculture through social movement dynamics, and to generate support from public policies and funds; and (v) participatory and quantitative methodologies can be combined for more precise and relevant assessments of agroecological transitions.


2012 ◽  
Vol 14 (2) ◽  
pp. 235-255 ◽  
Author(s):  
John Rees

This article considers some of the controversies that have troubled the Anglican Communion during the past 25 years, and some of the approaches that the Churches and central Instruments of the Communion have used to maintain communion in the face of threatened division. In particular, it looks in detail at the terms of the proposed Anglican Covenant, its provenance and its legal significance. It points out the usefulness of the Covenant as a mechanism for resolving disputes between the Churches of the Communion, but questions the assumption that its adoption as, in effect, a contract between the Churches would of itself turn the Communion into a ‘two-tier’ body, or change in a fundamental way the nature of the relationships between the Churches. Finally, it notes that communion between the Churches of the Anglican Communion, with or without the Covenant, consists (as it always has done) in a wide range of relationships at very many different levels, far beyond the central structures of the Communion as they have developed during the last 150 years.


Author(s):  
Naomi Oreskes

Plate tectonics is the unifying theory of modern geology. This theory, which holds that the major features of the earth’s surface are created by horizontal motions of the continents, has been hailed as the geological equivalent of the “theory of the Bohr atom in its simplicity, its elegance, and its ability to explain a wide range of observation,” in the words of A. Cox. Developed in the mid-1960s, plate tectonics rapidly took hold, so that by 1971, Gass, Smith, and Wilson could say in their introductory textbook in geology: . . . During the last decade, there has been a revolution in earth sciences . . . which has led to the wide acceptance that continents drift about the face of the earth and that the sea-floor spreads, continually being created and destroyed. Finally in the last two to three years, it has culminated in an all-embracing theory known as “plate tectonics.” The success of plate tectonics theory is not only that it explains the geophysical evidence, but that it also presents a framework within which geological data, painstakingly accumulated by land-bound geologists over the past two centuries, can be fitted. Furthermore, it has taken the earth sciences to the stage where they can not only explain what has happened in the past, and is happening at the present time, but can also predict what will happen in the future. . . . Today moving continents are a scientific fact. But some forty years before the advent of the theory of plate tectonics, a very similar theory, initially known as the “displacement hypothesis,” was proposed and rejected by the geological fraternity. In 1912, a German meteorologist and geophysicist, Alfred Wegener, proposed that the continents of the earth were mobile; in the decade that followed he developed this idea into a full-fledged theory of tectonics that was widely discussed and debated and came to be known as the theory of continental drift. To a modern geologist, raised in the school of plate tectonics, Wegener’s book, The Origin of Continents and Oceans, appears an impressive and prescient document that contains many of the essential features of plate tectonic theory.


1974 ◽  
Vol 5 (1) ◽  
pp. 1-17 ◽  
Author(s):  
Peter Krinks

SummaryThe homesteading system instituted in the Philippines in 1903 was intended to stimulate economic development through increased agricultural output from previously unoccupied lands and also to relieve agrarian problems in densely settled parts of the country. A case study shows that while early homesteaders did significantly improve their conditions, the intense demand for land rapidly led to the development of squatting and tenancy. Average farm sizes are declining but there are simultaneously indications of a trend towards concentration of land ownership, which accords with experience in other peasant economies.During the intense concern for economic development over the past 25 or so years, many governments have expressed their faith in the development of new agricultural land as at least a partial answer to a wide range of economic and social problems. These problems include regionally dense populations with inadequate farm sizes, inequitable systems of holding and renting land, inefficient methods of production and marketing, lack of capital and difficulties of capital formation, and low yields from land that is losing fertility through constant cropping. Frequently, ignorance, poverty or the agrarian structure inhibits the adoption of measures for improvement.Those countries with significant areas of little used land resources have tended to rely on developing these resources as an answer to agrarian problems rather than attempting to tackle defects in the whole structure. Since the structure is not changed, it is not surprising that in due course the firmly institutionalised problems of the older areas gradually established themselves in areas of new settlement too. This is essentially what Boeke referred to as “static expansion”. More recently, Mellor has pointed out, “Expanding the land area at constant productivity and incomes is not economic development in the usual sense — it is only a holding action in the face of a growing population”. Even with rising productivity such as associated with the Green Revolution, there is considerable evidence to suggest the continuation, if not exacerbation, of agrarian problems.By examining in detail a case study of colonisation in the Philippines, this paper will show that even if productivity and incomes in a new area are initially high, the operation of customary economic and social processes is likely to ensure the recreation of traditional problems. Such a conclusion is nothing new. It has been repeated depressingly often not only in recent decades but also of course throughout history.


Author(s):  
Thomas A. Prendergast ◽  
Stephanie Trigg

This chapter asks whether the mutual discontent we have diagnosed between medieval studies and medievalism is inevitable in future practice in these fields. Through its interest in recuperating the past, medievalism is an exemplary practice for the humanities and their understanding of history and culture. Facsimiles of medieval manuscripts further exemplify many of the similarities between medieval and medievalist study, and also our necessary discontent with most of the ways scholarship attempts to get back to and ‘touch’ the past. In the face of contemporary critiques of disciplinarity, we suggest that medieval and medievalism studies together are well placed to model new forms of academic engagement and resistance to the utilitarianism and vocationalism that increasingly dominates our universities. Productive engagement with the medieval past, from a wide range of disciplinary approaches, remains an urgent task for understanding the world around us.


Author(s):  
A. Strojnik ◽  
J.W. Scholl ◽  
V. Bevc

The electron accelerator, as inserted between the electron source (injector) and the imaging column of the HVEM, is usually a strong lens and should be optimized in order to ensure high brightness over a wide range of accelerating voltages and illuminating conditions. This is especially true in the case of the STEM where the brightness directly determines the highest resolution attainable. In the past, the optical behavior of accelerators was usually determined for a particular configuration. During the development of the accelerator for the Arizona 1 MEV STEM, systematic investigation was made of the major optical properties for a variety of electrode configurations, number of stages N, accelerating voltages, 1 and 10 MEV, and a range of injection voltages ϕ0 = 1, 3, 10, 30, 100, 300 kV).


2020 ◽  
Vol 04 (04) ◽  
pp. 369-372
Author(s):  
Paul B. Romesser ◽  
Christopher H. Crane

AbstractEvasion of immune recognition is a hallmark of cancer that facilitates tumorigenesis, maintenance, and progression. Systemic immune activation can incite tumor recognition and stimulate potent antitumor responses. While the concept of antitumor immunity is not new, there is renewed interest in tumor immunology given the clinical success of immune modulators in a wide range of cancer subtypes over the past decade. One particularly interesting, yet exceedingly rare phenomenon, is the abscopal response, characterized by a potent systemic antitumor response following localized tumor irradiation presumably attributed to reactivation of antitumor immunity.


2020 ◽  
Vol 1 (2) ◽  
pp. 157-172
Author(s):  
Thomas Leitch

Building on Tzvetan Todorov's observation that the detective novel ‘contains not one but two stories: the story of the crime and the story of the investigation’, this essay argues that detective novels display a remarkably wide range of attitudes toward the several pasts they represent: the pasts of the crime, the community, the criminal, the detective, and public history. It traces a series of defining shifts in these attitudes through the evolution of five distinct subgenres of detective fiction: exploits of a Great Detective like Sherlock Holmes, Golden Age whodunits that pose as intellectual puzzles to be solved, hardboiled stories that invoke a distant past that the present both breaks with and echoes, police procedurals that unfold in an indefinitely extended present, and historical mysteries that nostalgically fetishize the past. It concludes with a brief consideration of genre readers’ own ambivalent phenomenological investment in the past, present, and future each detective story projects.


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