scholarly journals 1528Ralteragir Containing regimen, for Post Exposure Prophylaxis (PEP), well tolerated in Health Care Workers (HCW)

2014 ◽  
Vol 1 (suppl_1) ◽  
pp. S405-S405
Author(s):  
Kassem Bourgi ◽  
Daniela Thompson ◽  
Dwayne Baxa ◽  
Indira Brar
Keyword(s):  
Health Care ◽  
Health Care Workers ◽  
Post Exposure Prophylaxis ◽  
Post Exposure ◽  
Care Workers ◽  
Exposure Prophylaxis

POST-EXPOSURE PROPHYLAXIS AGAINST HIV INFECTION IN HEALTH CARE WORKERS

The Lancet ◽  
1988 ◽  
Vol 331 (8583) ◽  
pp. 481 ◽  
Author(s):  
P.R. Meylan ◽  
P. Francioli ◽  
H. Decrey ◽  
J.Ph. Chave ◽  
M.P. Glauser
Keyword(s):  
Health Care ◽  
Hiv Infection ◽  
Health Care Workers ◽  
Post Exposure Prophylaxis ◽  
Post Exposure ◽  
Care Workers ◽  
Exposure Prophylaxis

An insight into Ribavirin post-exposure prophylaxis for Lassa fever infection prevention amongst health-care workers in a specialist hospital in North-Central Nigeria

2020 ◽  
Vol 22 (2) ◽  
pp. 122
Author(s):  
ChidiebereNwakamma Ononuju ◽  
LuckyLohnan Changkat ◽  
ChidozieValentine Adiukwu ◽  
OgediBlaise Okwaraoha ◽  
UzomaEmmanuel Chinaka ◽  
...  
Keyword(s):  
Health Care ◽  
Health Care Workers ◽  
Infection Prevention ◽  
Lassa Fever ◽  
Post Exposure Prophylaxis ◽  
North Central ◽  
Post Exposure ◽  
Care Workers ◽  
Exposure Prophylaxis ◽  
Insight Into

scholarly journals Post exposure prophylaxis for occupational and non occupational exposure to HIV in a tertiary care hospital in central Nepal

2018 ◽  
Vol 7 (2) ◽  
pp. 34-37
Author(s):  
Rakshya Shrestha ◽  
Sashi Sharma ◽  
Prem Khadga ◽  
Matina Sayami ◽  
Uma Chitrakar ◽  
...  
Keyword(s):  
Health Care ◽  
Antiretroviral Therapy ◽  
Occupational Exposure ◽  
Health Care Workers ◽  
Post Exposure Prophylaxis ◽  
Care Hospital ◽  
Staff Nurse ◽  
Post Exposure ◽  
Care Workers ◽  
Exposure Prophylaxis

Introduction: Post exposure prophylaxis (PEP) to HIV is the short term use of prescribed dose of antiretroviral therapy among persons exposed to high risk behaviors in order to prevent them from HIV infection. While occupationally exposed cases among health care workers are the major target of PEP, it is equally applicable to non occupational exposure to HIV including sexually exposed cases. This study was carried out to know the current scenario of PEP for HIV in terms of various determinants/ risk factors and outcomes of HIV positivity after prophylaxis. Methods: A prospective study was carried out by Antiretroviral therapy center of Tribhuvan University Teaching Hospital. The study period was between August 2006 and September 2016. Altogether 50 cases exposed to known HIV seropositive persons were included in this study. Results: The majority of the occupationally exposures were interns (48.6%), followed by staff nurse (18.9%), CMLT student (13.5%), hospital staff (10.8%) and resident doctor (8.1%). Majority (70.3%) were exposed to needle prick injury. Six-month follow-up showed zero seroconversion for HIV ELISA among the exposed cases. Conclusion: Intern constituted the greater proportion of health care workers exposed to accidental needle stick injury. Timely administration of prophylaxis might have resulted zero seroconversion for HIV ELISA among the exposed cases.

Tolerance, compliance and psychological consequences of post-exposure prophylaxis in health-care workers

1998 ◽  
Vol 9 (10) ◽  
pp. 591-594 ◽  
Author(s):  
X De La Tribonniere ◽  
M D Dufresne ◽  
S Alfandari ◽  
C Fontier ◽  
A Sobazek ◽  
...  
Keyword(s):  
Health Care ◽  
Adverse Events ◽  
Health Care Workers ◽  
Sexual Life ◽  
Post Exposure Prophylaxis ◽  
Psychological Consequences ◽  
Post Exposure ◽  
Care Workers ◽  
Hiv Seroconversion ◽  
Exposure Prophylaxis

Our objectives were to evaluate tolerance and compliance of postexposure triple therapy in health-care workers (HCWs) by retrospective observational study. Structured telephone interview of HCWs identified through data from antiretroviral prescribing centres. Twenty HCWs who received triple prophylaxis were identified over one year. Sixteen agreed to participate in the study. All but one source patient had documented HIV infection. Half HCWs were not aware of post-exposure therapy. Most HCWs received a zidovudine, lamivudine and indinavir combination. All completed at least 4 weeks of therapy. Only 50% received their first dosage less than 4 h after exposure. Nearly all experienced adverse events, mostly digestive (nausea and abdominal pain n =15) or psychological (anxiety and depression n =15), none resulting in therapy discontinuation. Most events occurred 2 to 7 days after therapy initiation. Most modified their sexual life with abstinence or condom use. Compliance was excellent. Half HCWs did not miss any tablet, 4 forgot one dosing a month and 4 one dosing a week. Follow up is over 6 months in all but one HCW. No HIV seroconversion has been observed to date. In France, post-exposure triple antiretroviral therapy is widely available 24 h a day in every emergency room but further training and development of HCWs is needed to decrease consulting time and increase referral to specialized physicians. Notable moderate adverse events, both physical and psychological are noted, however, compliance is excellent.

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