Experiments in Environment Integration

Author(s):  
Alan W. Brown ◽  
David J. Carney ◽  
Edwin J. Morris ◽  
Dennis B. Smith ◽  
Paul F. Zarrella

In assembling a CASE environment from a collection of commercial off-theshelf (COTS) tools, tool users must find ways to connect the tools such that they provide adequate support for their particular software development approach. This task takes place in the context of limited knowledge of the tools, limited access to the source or internal structures of the tools, limited resources with which to perform and maintain the tool connections, and evolving understanding of the needs of the tool users. This places severe restrictions on what can be attempted in terms of tool interconnection. Environment framework technologies (e.g., ECMA PCTE, ATIS, BMS, ToolTalk, or CORBA) claim to provide a set of common integration services that aid in the tool integration process. There have been numerous discussions about the value, maturity, and complexity of these framework technologies. Such discussions are characterized by three points: general agreement that framework technology per se is a valuable goal to pursue; moderate disagreement as to whether the current level of framework technology is a sufficient basis for production quality CASE environments; and considerable disagreement about which of the current technologies are the most likely to mature and succeed. Notable about these discussions, however, is that there has not been extensive use of the technologies in question. This stems from several sources: their expense, their unfamiliarity and complexity to current tool users, and a widespread concern about their immaturity. This lack of use is perhaps understandable, but it has had the additional effect that partisans of one or another technology have made assertions based on little factual information about the relative merits of the technology in question. To expand our own expertise in tool integration and framework technologies, and to answer the question, “What tool integrations are possible for third-party tool users given the current state of COTS tools and integration technology?” we performed a set of experiments involving the integration of a collection of common COTS tools with environment framework technologies in support of a typical development scenario. Our selection of these tools and technologies was based on common availability and application to the development scenario(s) of interest.

2019 ◽  
pp. 4-44 ◽  
Author(s):  
Peter Thorns

This paper discusses the organisations involved in the development of application standards, European regulations and best practice guides, their scope of work and internal structures. It considers their respective visions for the requirements for future standardisation work and considers in more detail those areas where these overlap, namely human centric or integrative lighting, connectivity and the Internet of Things, inclusivity and sustainability.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Nicole Pretini ◽  
Leonardo S. Vanzetti ◽  
Ignacio I. Terrile ◽  
Guillermo Donaire ◽  
Fernanda G. González

Abstract Background In breeding programs, the selection of cultivars with the highest yield potential consisted in the selection of the yield per se, which resulted in cultivars with higher grains per spike (GN) and occasionally increased grain weight (GW) (main numerical components of the yield). In this study, quantitative trait loci (QTL) for GW, GN and spike fertility traits related to GN determination were mapped using two doubled haploid (DH) populations (Baguette Premium 11 × BioINTA 2002 and Baguette 19 × BioINTA 2002). Results In total 305 QTL were identified for 14 traits, out of which 12 QTL were identified in more than three environments and explained more than 10% of the phenotypic variation in at least one environment. Eight hotspot regions were detected on chromosomes 1A, 2B, 3A, 5A, 5B, 7A and 7B in which at least two major and stable QTL sheared confidence intervals. QTL on two of these regions (R5A.1 and R5A.2) have previously been described, but the other six regions are novel. Conclusions Based on the pleiotropic analysis within a robust physiological model we conclude that two hotspot genomic regions (R5A.1 and R5A.2) together with the QGW.perg-6B are of high relevance to be used in marker assisted selection in order to improve the spike yield potential. All the QTL identified for the spike related traits are the first step to search for their candidate genes, which will allow their better manipulation in the future.


2021 ◽  
Vol 22 (8) ◽  
pp. 3949
Author(s):  
Lidia Wlodarczyk ◽  
Rafal Szelenberger ◽  
Natalia Cichon ◽  
Joanna Saluk-Bijak ◽  
Michal Bijak ◽  
...  

Several key issues impact the clinical practice of stroke rehabilitation including a patient’s medical history, stroke experience, the potential for recovery, and the selection of the most effective type of therapy. Until clinicians have answers to these concerns, the treatment and rehabilitation are rather intuitive, with standard procedures carried out based on subjective estimations using clinical scales. Therefore, there is a need to find biomarkers that could predict brain recovery potential in stroke patients. This review aims to present the current state-of-the-art stroke recovery biomarkers that could be used in clinical practice. The revision of biochemical biomarkers has been developed based on stroke recovery processes: angiogenesis and neuroplasticity. This paper provides an overview of the biomarkers that are considered to be ready-to-use in clinical practice and others, considered as future tools. Furthermore, this review shows the utility of biomarkers in the development of the concept of personalized medicine. Enhancing brain neuroplasticity and rehabilitation facilitation are crucial concerns not only after stroke, but in all central nervous system diseases.


2021 ◽  
Vol 48 (2) ◽  
pp. 119-129
Author(s):  
Lilyana Lesnichkova ◽  

The article focuses on the presentation of the Hungarian-Bulgarian valence dictionary, which is currently in preparation, against the background of an extremely actual task – the creation of an academic English-Bulgarian dictionary, adequately reflecting the current state of vocabulary in both languages. The author substantiates the need for such a dictionary, given the lack of general and specialized Hungarian-Bulgarian dictionaries, based on the theoretical foundations and principles of modern lexicography. Outlined are the main features of the dictionary, the specificities and approaches in the work of its compilation. The selection of material and the methods of its presentation are in accordance with the practical needs of learners of Hungarian as a foreign language.


2018 ◽  
Vol 33 ◽  
pp. 03058
Author(s):  
Denis Sinitsyn

The article covers one of the preparatory works types, in particular – the debris clearance. The types of machines and machinery, the purposes of the debris clearance, as well as the tasks for decrease of debris mass and scope are specified herein. The purpose of the article is to show the current level of the domestic machinery, as well as to share the experience of preparatory works. The article describes one of the preparatory works types, in particular – the debris clearance during the high-rise buildings demolition. Given are the equipment and machinery types, covered are the purposes and procedure of debris clearance defined are the tasks on reduction of debris mass and sizes. Specified are the types and methods of the preparatory works execution. The purpose of this article is to demonstrate the domestic equipment current state, and to share the experience in preparatory works execution.


2021 ◽  
Vol 13 (2) ◽  
pp. 59-78
Author(s):  
Olena Kotykova ◽  
Mykola Babych

An effective implementation of the sustainable use of agricultural land program is impossible without reliable results of the current state of the problem. In this sense, the correct selection of indicators and methods for determining the level of stability is important. The authors proposes the definition of the agricultural land use sustainability integral indicator based on three methodological approaches: the construction of the indicators system, each of them reflects some aspects of the land use sustainability at the macro level (according to the specific issues); the construction of the integral indicator for comparing the countries’ land use sustainability. According to the given methods it has been proved that agricultural land use in the countries of the post-socialist camp has a positive dynamics, but the sustainability indicators for all indicators have not achieved yet. This study was supported in part by the Erasmus SUPPA program – Jean Monnet Associations Application No 611556-EPP-1-2019-1-UA-EPPJMO-SUPPA.


2021 ◽  
Vol 12 (1) ◽  
pp. 135-146
Author(s):  
E.A. Ejem ◽  
C.M. Uka ◽  
D.N. Dike ◽  
C.C. Ikeogu ◽  
C.C. Igboanusi ◽  
...  

Abstract This paper is focused on solving the evaluation and selection of 3PL’s by applying multi-criteria decision-making methods. Nigerian Breweries, Nigerian Bottling Company (NBC), AG Leventis, Kobo logistics, and Flour Mills of Nigeria (FMN) were understudied. The main criteria on which evaluation is based were established: Cost, Service level, Financial Capability, Reputation and Long-term relationship. A combination of two quantitative models was adopted in the study. Relevant data were collected through an oral interview with managers and key decision-makers at the companies. SWARA was first applied to the collated data to determine the relative weights of the criteria. Afterwards, the TOPSIS was applied to the weights developed using SWARA and on the performance of the selected service providers. After the analysis, the best service provider was identified as supplier 2 while the worst was supplier 5.


2021 ◽  
Vol 1 (2) ◽  
pp. 2-20
Author(s):  
N. A. Shnayder ◽  
K. V. Petrov

Due to the high prevalence of the disease, its genetic and clinical heterogeneity, the need for lifelong therapy and the emergence of new views on the pathogenesis and course of JME, it is necessary to provide primary care physicians (general practitioners, district therapists, neurologists) with up-to-date systematized information about the most common form of genetic generalized epilepsy (Herpin-Janz syndrome). JME is a genetically determined disease of the brain, accompanied by a triad of seizures (absences, myoclonia, generalized tonic-clonic seizures), and developing mainly in adolescence and young age. In recent years, monogenic and multifactorial forms of JME have been identified, but questions about the genetics of JME are far from being resolved. JME is characterized by the preservation of intelligence, life expectancy with adequate therapy does not differ from the average population, but the frequency of failures of pharmaco-induced remission is high when taking anticonvulsants is canceled. This explains the need for lifelong pharmacotherapy, individual selection of anticonvulsants. About 30% of patients with JME have non-psychotic mental disorders, disorders of the sleep and wake cycle, which in turn leads to an aggravation of epileptic seizures mainly in the first half of the day. This review presents an analysis of full-text publications in Russian and English over the past five years in the databases eLibrary, PubMed, Web of Science, OxfordPress, Springer, and Clinicalkeys. In addition, the review includes earlier publications of historical significance.


Author(s):  
Weixiang Xu ◽  
Xiangyu He ◽  
Tianli Zhao ◽  
Qinghao Hu ◽  
Peisong Wang ◽  
...  

Large neural networks are difficult to deploy on mobile devices because of intensive computation and storage. To alleviate it, we study ternarization, a balance between efficiency and accuracy that quantizes both weights and activations into ternary values. In previous ternarized neural networks, a hard threshold Δ is introduced to determine quantization intervals. Although the selection of Δ greatly affects the training results, previous works estimate Δ via an approximation or treat it as a hyper-parameter, which is suboptimal. In this paper, we present the Soft Threshold Ternary Networks (STTN), which enables the model to automatically determine quantization intervals instead of depending on a hard threshold. Concretely, we replace the original ternary kernel with the addition of two binary kernels at training time, where ternary values are determined by the combination of two corresponding binary values. At inference time, we add up the two binary kernels to obtain a single ternary kernel. Our method dramatically outperforms current state-of-the-arts, lowering the performance gap between full-precision networks and extreme low bit networks. Experiments on ImageNet with AlexNet (Top-1 55.6%), ResNet-18 (Top-1 66.2%) achieves new state-of-the-art.


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