HLA ASSOCIATIONS IN SUBJECTS WITH RHEUMATOID ARTHRITIS AND BRONCHIECTASIS BUT NOT WITH OTHER PULMONARY COMPLICATIONS OF RHEUMATOID DISEASE

Rheumatology ◽  
1993 ◽  
Vol 32 (9) ◽  
pp. 794-797 ◽  
Author(s):  
M. C. HILLARBY ◽  
M. J. McMAHON ◽  
D. M. GRENNAN ◽  
R. G. COOPER ◽  
R. W. E. CLARKSON ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Pulmonary Complications ◽  
Rheumatoid Disease

The Wrightington Classification of Rheumatoid Wrist X-Rays: A Guide to Surgical Management

1989 ◽  
Vol 14 (4) ◽  
pp. 451-455
Author(s):  
S. P. HODGSON ◽  
J. K. STANLEY ◽  
A. MUIRHEAD
Keyword(s):  
Rheumatoid Arthritis ◽  
Surgical Management ◽  
X Rays ◽  
Rheumatoid Disease ◽  
Rheumatoid Wrist ◽  
Practical Guidance ◽  
Surgical Choices ◽  
Results Of Surgery

We have reviewed the pre-operative radiological appearances, the type of operation performed and the results of surgery of 234 wrists in 179 patients with rheumatoid arthritis. Based on this, a classification of X-rays of the rheumatoid wrist is described. It is designed to provide practical guidance to the surgeon who is planning surgery in a patient with rheumatoid disease. The surgical choices at each stage of the disease are briefly discussed.

Studies on the Vasculopathy of Rheumatoid Arthritis and Its Relation to “Systemic Rheumatoid Disease”

Arthritis ◽  
1981 ◽  
pp. 118-134 ◽  
Author(s):  
H. Deicher ◽  
H. Mielke ◽  
W. Daniel ◽  
W. Drommer ◽  
M. Fischer ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Rheumatoid Disease

scholarly journals Methotrexate-related pulmonary complications in rheumatoid arthritis.

1994 ◽  
Vol 53 (7) ◽  
pp. 434-439 ◽  
Author(s):  
P Barrera ◽  
R F Laan ◽  
P L van Riel ◽  
P N Dekhuijzen ◽  
A M Boerbooms ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Pulmonary Complications

scholarly journals Clinical evaluation of DMARDs and NSAIDs in cases of Rheumatoid arthritis in Chhattisgarh

2018 ◽  
Vol 9 (1) ◽  
pp. 61-64
Author(s):  
Basant Kumar Maheshwari ◽  
Prafulla Kumar Khodiar ◽  
Debapriya Rath
Keyword(s):  
Rheumatoid Arthritis ◽  
Medical Sciences ◽  
Rheumatoid Disease ◽  
Disease Modifying Drugs ◽  
Serological Examination ◽  
Inflammatory Drugs ◽  
Disease Modifying ◽  
Disease Modifying Agents ◽  
Systemic Symptoms ◽  
Group 1

Background: Rheumatoid arthritis (RA) is an autoimmune disease characterized by polyarticular inflammation with systemic symptoms like malaise, fatigue and fever. Various groups of drugs have been used along with supportive therapies (physical and occupational) for the treatment of rheumatoid arthritis. Non-steroidal anti-inflammatory drugs (NSAIDs) and disease modifying agents in rheumatoid disease (DMARDs) are the two major classes among them. However, none of these medications have proved to be successful enough to be accepted universally as the standard therapy for RA.Aims and Objective: To compare the clinical efficacy of nimesulide as a standalone therapy with combination therapy of nimesulide plus methotrexate and nimesulide plus hydroxychloroquine.Materials and Methods: The study comprised of three groups of rheumatoid arthritis patients. Each group consists of 32 study subjects. Group 1, 2 and 3 consisted of patients taking nimesulide alone, nimesulide plus hydroxycholoroquine and nimesulide plus methotrexate respectively for the disease. The cases were followed up to a period of six months and based upon subjective & objective (Radiological and serological examination) criteria, results have been evaluated.Results: Observations have revealed that nimesulide plus hydroxycholoroquine combination produced significant improvement in the patients in mild, moderate and severe cases of rheumatoid arthritis as compared to nimesulide plus methotrexate. The improvement observed was least in the patients who received nimesulide as standalone therapy. No significant adverse drug reaction was seen in any of the study groups.Conclusion: The study concludes that nimesulide plus hydroxychloroquine combination can be used in cases of rheumatoid arthritis as disease modifying drugs without noticeable toxicity in doses used in this study in patients who have no renal and hepatic insufficiency.Asian Journal of Medical Sciences Vol.9(1) 2018 61-64

Safety of Biologic Agents in Elderly Patients with Rheumatoid Arthritis

2016 ◽  
Vol 43 (11) ◽  
pp. 1984-1988 ◽  
Author(s):  
Atsuko Murota ◽  
Yuko Kaneko ◽  
Kunihiro Yamaoka ◽  
Tsutomu Takeuchi
Keyword(s):  
Rheumatoid Arthritis ◽  
Risk Factors ◽  
Adverse Events ◽  
Elderly Patients ◽  
Young Patients ◽  
Pulmonary Complications ◽  
Biologic Agents ◽  
Treatment Withdrawal ◽  
Old Patients ◽  
Independent Risk Factors

Objective.To clarify the safety of biologics in elderly patients with rheumatoid arthritis.Methods.Biologics were analyzed for safety in relation to age in 309 patients.Results.Young (< 65 yrs old, n = 174), elderly (65–74 yrs old, n = 86), and older elderly patients (≥ 75 yrs old, n = 49) were enrolled. Although the incidence of adverse events causing treatment withdrawal was significantly higher in elderly and old elderly compared with young patients, no difference was found between elderly and older elderly patients. Pulmonary complications were independent risk factors.Conclusion.Old patients require special attention, although the safety of biologics in those ≥ 75 years old and 65–74 was comparable.

scholarly journals MANAGEMENT OF KNEE RHEUMATOID ARTHRITIS WITH TOTAL KNEE ARTHROPLASTY: A SYSTEMATIC REVIEW

2017 ◽  
Vol 26 (4) ◽  
pp. 149-153
Author(s):  
Calin Dragosloveanu ◽  
◽  
Serban Dragosloveanu ◽  
Bogdan Cretu ◽  
◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Total Knee Arthroplasty ◽  
Knee Arthroplasty ◽  
Daily Living ◽  
Structural Damage ◽  
Marked Decrease ◽  
Rheumatoid Disease ◽  
Anesthetic Considerations ◽  
Total Knee ◽  
Results Of Surgery

Total knee arthroplasty (TKA) in patients with rheumatoid arthritis (RA) has different features from those seen in patients with osteoarthritis. In 1970 85% of the patients undergoing TKA had rheumatoid arthritis. Nowadays less than 5% of the patients undergoing TKA have rheumatoid disease. An important reason for the marked decrease is the improvement of the medical treatment. Fewer patients now progress to permanent structural damage requiring arthroplasty. TKA in RA has management difficulties that are unique to the disease. These include ipsilateral hip involvement, bilaterality, anticoagulation needs, flexion contractures, rheumatoid cysts and possibly the need for synovectomy. Patients with rheumatoid arthritis are more vulnerable to both early and late infections. They require a prosthesis and technique that provide adequate flexion for activities of daily living. Their often-profound osteopenia can lead to intraoperative and postoperative fractures. Finally, their cervical spine and temporal-mandibular disease create challenging anesthetic considerations. Nevertheless, given these considerations and the degree of preoperative disability suffered by patients with rheumatoid arthritis, the results of surgery can be extremely dramatic and gratifying to both patient and surgeon.

Rupture of Flexor Tendons to the Little Finger Due to Bony Irregularities in the Carpal Tunnel

1988 ◽  
Vol 13 (3) ◽  
pp. 308-310
Author(s):  
T. R. STEVENSON ◽  
D. S. LOUIS ◽  
S. E. ZUCKER
Keyword(s):  
Rheumatoid Arthritis ◽  
Rough Surface ◽  
Carpal Tunnel ◽  
Flexor Tendon ◽  
Ring Finger ◽  
Rheumatoid Disease ◽  
Flexor Tendons ◽  
Flexor Retinaculum ◽  
Little Finger

Rupture of a finger flexor tendon occurs most commonly in the patient with rheumatoid arthritis. We have treated two patients who suffered rupture of the flexor tendons to the little finger due to bony irregularities in the carpal tunnel unrelated to rheumatoid disease. Each irregularity was removed and the rough surface covered with a portion of the flexor retinaculum. This resurfacing affords protection against recurrent abrasion and rupture. Tendon function was restored by suturing the ruptured profundus tendon to the adjacent intact profundus tendon of the ring finger. Satisfactory function of the little finger was achieved in both patients. Neither patient has experienced recurrent rupture.

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