Intra-operative frozen section technique for pituitary adenomas

1979 ◽  
Vol 3 (2) ◽  
pp. 173-175 ◽  
Author(s):  
Lester S. Adelman ◽  
Kalmon D. Post
2002 ◽  
Vol 4 (2) ◽  
pp. 114-119 ◽  
Author(s):  
Stuart H. Bentkover ◽  
Donald M. Grande ◽  
Henry Soto ◽  
Beth A. Kozlicak ◽  
Donna Guillaume ◽  
...  

1999 ◽  
Vol 91 (3) ◽  
pp. 454-458 ◽  
Author(s):  
Katrina S. Firlik ◽  
A. Julio Martinez ◽  
L. Dade Lunsford

Object. The goals of this study were to analyze the accuracy of cytological techniques, consisting of touch and smear preparations, for the intraoperative diagnosis of stereotactically obtained brain biopsy samples, and to determine the prevalence of the use of these methods among neuropathologists.Methods. A survey regarding preferred methods for intraoperative diagnosis of stereotactically obtained brain biopsy samples was completed by 92 (62%) of 148 neuropathologists. Twenty-three percent of respondents chose frozen-section examination alone; 13% chose one or more cytological methods alone; and the remainder (64%) chose a combination of frozen-section examination and cytology.At the University of Pittsburgh, the neuropathology records for all stereotactic brain biopsies performed from May 1979 through May 1998 were retrospectively reviewed. Of the 946 stereotactic brain biopsies, 316 cases were excluded because the intraoperative neuropathological consultation was not recorded. Thirty-five cases were excluded because frozen-section examinations were performed. Therefore, a total of 595 cases were suitable for analysis.Intraoperative cytological investigation correlated with the final diagnosis in 90% of cases (52% complete correlation and 38% partial correlation). In 11% of cases there was no correlation between the intraoperative and final diagnoses. Intraoperative diagnoses were most accurate in cases of abscess, germinoma, lymphoma, metastasis, and malignant glioma.Overall, 91% of biopsy specimens were diagnostic when examined using the paraffin-embedded section technique. The sensitivity of cytological preparations in detecting a diagnostic specimen was 96% and the specificity in detecting a nondiagnostic specimen was 75%.Conclusions. Intraoperative cytological preparations correlated with the final diagnoses in 90% of stereotactic biopsies and had a 96% sensitivity in detecting diagnostic specimens. The highest rate of correlation was noted in cases of abscess, germinoma, lymphoma, metastasis, and malignant glial tumor.


1985 ◽  
Author(s):  
Seung H. Kim ◽  
Gene B. Hubbard ◽  
William F. McManus ◽  
Arthur D. Mason ◽  
Pruitt Jr. ◽  
...  

2017 ◽  
Vol 26 (1) ◽  
pp. 61-66 ◽  
Author(s):  
Yasuko Takahashi ◽  
Miwa Kanou ◽  
Yuichi Ito ◽  
Michi Ohmori ◽  
Kayoko Yamamoto ◽  
...  

2019 ◽  
Vol 22 (6) ◽  
pp. 558-565
Author(s):  
Ramesh Babu ◽  
Pavithra Vittalraj ◽  
Sandhya Sundaram ◽  
Mullappali Pothankulankara Manjusha ◽  
Venkat Ramanan ◽  
...  

Background The exact etiology of ureteropelvic junction obstruction (UPJO) is unknown, and inadequate excision of the narrow segment has been proposed as a cause of failure in 5% to 7% of cases of pyeloplasty. Aims To study whether frozen section can be useful to detect normal ureter distal to UPJO during pyeloplasty. Methods Histological sections from 31 patients with UPJO were analyzed for collagen to muscle ratio (CMR) on conventional (formalin) and rapid (frozen section) Masson’s trichrome staining. Pathological findings were correlated with postoperative outcomes analyzed at 1-year follow-up and expressed as excellent, moderate, or mild improvement, static and deterioration based on ultrasound grade, differential renal function, and renogram drainage pattern. Results There was a very strong positive correlation ( r = .94; P = .001) between CMR by conventional and rapid frozen Masson’s trichrome staining. There was a very strong negative correlation between pyeloplasty outcomes and CMR on conventional staining ( r = −.94; P = .001) or rapid frozen Masson’s trichrome staining ( r = −.91; P = .001). Regression analysis revealed that a CMR of 1.2 or less (95% confidence interval: 1.9–0.7) was associated with a successful outcome. Conclusions It is feasible to intraoperatively identify normal ureter distal to UPJO using CMR analysis on the novel rapid frozen section technique reported.


1959 ◽  
Vol 10 (6) ◽  
pp. 886 ◽  
Author(s):  
T Nay ◽  
JA Bathgate ◽  
J Beeston

A new simplified technique for obtaining histological sections of sheep and cattle skin is described, with details of the freezing microtome necessary for the technique.


2005 ◽  
Vol 129 (12) ◽  
pp. 1532-1535 ◽  
Author(s):  
Anthony A. Gal

Abstract The frozen section technique has become an invaluable tool to assist the surgeon with intraoperative diagnosis. Although there were various descriptions of frozen section technique before and after the turn of the 20th century, the publication by Louis B. Wilson, MD, at the Mayo Clinic in 1905 heralded the beginning of a new era in intraoperative diagnosis. This historical review traces the circumstances that led to this landmark publication 100 years ago.


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