A687 EFFECTS OF PROPOFOL ON MITOCHONDRIAL OXIDATIVE PHOSPHORYLATION IN RAT LIVER

1990 ◽  
Vol 73 (3A) ◽  
pp. NA-NA
Author(s):  
P. Bendriss ◽  
I. Nelson ◽  
P. Dabadie ◽  
J. P. Mazat
Keyword(s):  
Oxidative Phosphorylation ◽  
Rat Liver ◽  
Mitochondrial Oxidative Phosphorylation

Mitochondrial oxidative phosphorylation and intracellular glutathione compartmentation during rat liver regeneration

Hepatology ◽  
1995 ◽  
Vol 21 (5) ◽  
pp. 1450-1454 ◽  
Author(s):  
Gianluigi Vendemiale ◽  
Ferruccio Guerrieri ◽  
Ignazio Grattagliano ◽  
Domenico Didonna ◽  
Leonilde Muolo ◽  
...  
Keyword(s):  
Oxidative Phosphorylation ◽  
Liver Regeneration ◽  
Rat Liver ◽  
Mitochondrial Oxidative Phosphorylation ◽  
Rat Liver Regeneration ◽  
Intracellular Glutathione

Alterations of rat liver mitochondrial oxidative phosphorylation and calcium uptake by benzo[a]pyrene

2004 ◽  
Vol 198 (1) ◽  
pp. 1-10 ◽  
Author(s):  
Inés Salazar ◽  
Mario Pavani ◽  
Waldo Aranda ◽  
Juan Diego Maya ◽  
Antonio Morello ◽  
...  
Keyword(s):  
Oxidative Phosphorylation ◽  
Rat Liver ◽  
Calcium Uptake ◽  
Mitochondrial Oxidative Phosphorylation

scholarly journals In Vivo Effect of Uncoupling Agents on the Incorporation of Calcium and Strontium into Mitochondria and Other Subcellular Fractions of Rat Liver

1967 ◽  
Vol 50 (7) ◽  
pp. 1849-1864 ◽  
Author(s):  
E. Carafoli
Keyword(s):  
Oxidative Phosphorylation ◽  
Rat Liver ◽  
Liver Cell ◽  
Intact Animal ◽  
Specific Activity ◽  
Mitochondrial Fraction ◽  
Liver Cells ◽  
Subcellular Fractions ◽  
Mitochondrial Oxidative Phosphorylation

After injection of 45Ca++ or 89Sr++ into rats, the largest part of the radioactivity in the liver cell is associated with the subcellular structures, only negligible amounts of it being found in the soluble hyaloplasm. 50 % or more of the 45Ca++ and 89Sr++ in the liver cell is recovered in the mitochondrial fraction. The specific activity of Ca++ after injection of 45Ca++ is far greater in mitochondria than in microsomes. Pretreatment of the rats with uncouplers of oxidative phosphorylation markedly decreases the amount of radioactivity associated with the mitochondrial fraction. The amount of radioactivity recovered in the microsomes and in the final supernatant on the contrary increases. These effects are present only when mitochondrial oxidative phosphorylation is completely uncoupled. The Ca++ content of mitochondria from the livers of rats pretreated with uncouplers is sharply decreased with respect to the controls. It is concluded that in the liver cells of the intact animal energy-linked movements of Ca++ and Sr++ take place in mitochondria.

Dependence of Platelet Adenyl Cyclase System on Oxidative Phosphorylation

1975 ◽  
Vol 34 (01) ◽  
pp. 042-049 ◽  
Author(s):  
Shuichi Hashimoto ◽  
Sachiko Shibata ◽  
Bokro Kobayashi
Keyword(s):  
Cyclic Amp ◽  
Oxidative Phosphorylation ◽  
Sodium Succinate ◽  
Potassium Cyanide ◽  
Adenyl Cyclase ◽  
Mitochondrial Oxidative Phosphorylation ◽  
Adenyl Cyclase Activity ◽  
Intact Rabbit ◽  
Adenyl Cyclase System ◽  
Cyclic Amp Synthesis

SummaryThe radioactive adenosine 3′,5′-monophosphate (cyclic AMP) level derived from 8-14C adenine in intact rabbit platelets decreased in the presence of mitochondrial inhibitor (potassium cyanide) or uncoupler (sodium azide), and markedly increased by the addition of NaF, monoiodoacetic acid (MIA), or 2-deoxy-D-glucose. The stimulative effect of the glycolytic inhibitors was distinctly enhanced by the simultaneous addition of sodium succinate. MIA did neither directly stimulate the adenyl cyclase activity nor inhibit the phosphodiesterase activity. These results suggest that cyclic AMP synthesis in platelets is closely linked to mitochondrial oxidative phosphorylation.

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