An Algorithm for Quantifying Blood Pressure Lability 

1997 ◽  
Vol 87 (6) ◽  
pp. 1593-1594
Author(s):  
Aaron I. Cohn
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Lability

Standardized Autonomic Testing in Patients With Probable Radiation-Induced Afferent Baroreflex Failure

Hypertension ◽  
2021 ◽  
Author(s):  
Guillaume Lamotte ◽  
Elizabeth A. Coon ◽  
Mariana D. Suarez ◽  
Paola Sandroni ◽  
Eduardo Benarroch ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Monitoring ◽  
Sweat Test ◽  
Plasma Norepinephrine ◽  
Pressure Monitoring ◽  
Autonomic Testing ◽  
Baroreflex Failure ◽  
Radiation Induced ◽  
Thermoregulatory Sweat Test ◽  
Blood Pressure Lability

Injury of the afferent limb of the baroreflex from neck radiation causes radiation-induced afferent baroreflex failure (R-ABF). Identification and management of R-ABF is challenging. We aimed to investigate the pattern of autonomic dysfunction on standardized autonomic testing in patients with probable R-ABF. We retrospectively analyzed all autonomic reflex screens performed at Mayo Clinic in Rochester, MN, between 2000 and 2020 in patients with probable R-ABF. Additional tests reviewed included ambulatory blood pressure monitoring, plasma norepinephrine, and thermoregulatory sweat test. We identified 90 patients with probable R-ABF. Median total composite autonomic severity score (range, 0–10) was 7 (interquartile range, 6–7). Cardiovascular adrenergic impairment was seen in 85 patients (94.4%), increased blood pressure recovery time after Valsalva maneuver in 71 patients (78.9%; median 17.4 seconds), and orthostatic hypotension in 68 patients (75.6%). Cardiovagal impairment was demonstrated by abnormal heart rate responses to deep breathing (79.5%), Valsalva ratio (87.2%), and vagal baroreflex sensitivity (57.9%). Plasma norepinephrine was elevated and rose appropriately upon standing (722–1207 pg/mL). Ambulatory blood pressure monitoring revealed hypertension, postural hypotension, hypertensive surges, tachycardia, and absence of nocturnal dipping. Blood pressure lability correlated with impaired vagal baroreflex function. Postganglionic sympathetic sudomotor function was normal in most cases; the most frequent thermoregulatory sweat test finding was focal neck anhidrosis (78.9%). Standardized autonomic testing in R-ABF demonstrates cardiovascular adrenergic impairment with orthostatic hypotension, blood pressure lability, and elevated plasma norepinephrine. Cardiovagal impairment is common, while sudomotor deficits are limited to direct radiation effects.

Blood pressure lability is associated with subcortical atrophy in early Parkinson's disease

2020 ◽  
Vol 38 (10) ◽  
pp. 2043-2049
Author(s):  
Sang-Won Yoo ◽  
Eunkyeong Yun ◽  
Mirim Bang ◽  
Uicheul Yoon ◽  
Ji-Yeon Yoo ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Early Parkinson’S Disease ◽  
Blood Pressure Lability

6. Hemodynamic analysis of blood pressure lability after chronic sympathectomy in the conscious rat

1991 ◽  
Vol 9 (6) ◽  
pp. S423
Author(s):  
C. Barres ◽  
I. Cantalupi ◽  
Claude Julien ◽  
Jean Sassard
Keyword(s):  
Blood Pressure ◽  
Conscious Rat ◽  
Blood Pressure Lability

scholarly journals Effects of Preoperative Drug Therapy on Perioperative Blood Pressure Lability in Hypertensive Patients.

2002 ◽  
Vol 22 (4) ◽  
pp. 167-171
Author(s):  
Yoshiko MIZUNO ◽  
Yoshiyuki NAITO ◽  
Seiki ABE ◽  
Emi OIDA ◽  
Yuji OTSUKA ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Drug Therapy ◽  
Hypertensive Patients ◽  
Blood Pressure Lability

scholarly journals Intraoperative arterial blood pressure lability is associated with improved 30 day survival

2015 ◽  
Vol 115 (5) ◽  
pp. 716-726 ◽  
Author(s):  
M.A. Levin ◽  
G.W. Fischer ◽  
H.-M. Lin ◽  
P.J. McCormick ◽  
M. Krol ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Arterial Blood Pressure ◽  
Arterial Blood ◽  
Blood Pressure Lability

An Algorithm for Assessing Intraoperative Mean Arterial Pressure Lability 

1997 ◽  
Vol 87 (1) ◽  
pp. 156-161 ◽  
Author(s):  
David L. Reich ◽  
Todd K. Osinski ◽  
Carol Bodian ◽  
Marina Krol ◽  
Kaya Sarier ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Fractional Change ◽  
Absolute Value ◽  
Anesthesia Practice ◽  
Precise Data ◽  
Blood Pressure Lability ◽  
Collection Methods ◽  
Arterial Pressure Lability

Background Intraoperative blood pressure lability may be related to risk factors, hypovolemia, light anesthesia, and morbid outcomes, but the measurements of lability in previous studies have been limited by imprecise and infrequent data collection methods. Computerized intraoperative data acquisition systems have provided an opportunity to readdress the issue of intraoperative blood pressure lability with more abundant and precise data. This study sought to derive and validate an algorithm (expert system) to measure mean arterial pressure (MAP) lability. Methods Two hundred thirty-nine computerized anesthesis records were reviewed retrospectively. Three anesthesiologists separately rated MAP as very stable, average, or very labile. The parameters of a computer algorithm that measured the change of median MAP between consecutive 2-min epochs were optimized to achieve the best possible agreement among the anesthesiologists. The algorithm was then validated on 229 additional anesthesia records. Results The proportion of consecutive 2-min epochs in which the absolute value of the fractional change of median MAP exceeded 0.06 (i.e., 6%) correlated strongly with the anesthesiologists' ratings (r = 0.78; P < 0.0001). The optimal sensitivity and specificity of the algorithm for detecting MAP lability were 98% and 59%, respectively. Conclusions One potential application of expert systems to anesthesia practice is a "smart alarm" to detect blood pressure lability. It may also provide a better tool to assess the relation between lability and outcome than has been available previously.

6. Hemodynamic analysis of blood pressure lability after chronic sympathectomy in the conscious rat

1991 ◽  
Vol 9 ◽  
pp. S423
Author(s):  
C. Barres ◽  
I. Cantalupi ◽  
Claude Julien ◽  
Jean Sassard
Keyword(s):  
Blood Pressure ◽  
Conscious Rat ◽  
Blood Pressure Lability

Diminished Blood Pressure Lability in Ageing Rats

Gerontology ◽  
1958 ◽  
Vol 2 (1) ◽  
pp. 47-54 ◽  
Author(s):  
S.M. Friedman ◽  
A.G. Middleton ◽  
Constance Friedman
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Lability
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