Survival is prolonged by highly active antiretroviral therapy in AIDS patients with primary central nervous system lymphoma

AIDS ◽  
2003 ◽  
Vol 17 (12) ◽  
pp. 1787-1793 ◽  
Author(s):  
Daniel J Skiest ◽  
Craig Crosby
2021 ◽  
pp. 931-948
Author(s):  
Akanksha Sharma ◽  
Alyx B. Porter

Primary central nervous system lymphoma (PCNSL) is a rare variant of extranodal non-Hodgkin lymphoma that may involve the brain, leptomeninges, eyes, or spinal cord and accounts for up to 5% of all adult primary brain neoplasms. Age-adjusted incidence has increased in the past 3 decades. Infection with HIV and acquired immunodeficiency syndrome increase the risk of PCNSL by 3,600-fold. However, with highly active antiretroviral therapy, the frequency of immune system compromise sufficient for HIV-associated PCNSL (CD4 count ≤50) is dramatically reduced, along with the risk of this disorder.


2005 ◽  
Vol 11 (0) ◽  
pp. 72-82 ◽  
Author(s):  
Christian Manzardo ◽  
María del Mar Ortega ◽  
Omar Sued ◽  
Felipe García ◽  
Asunción Moreno ◽  
...  

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